ZNF177 protein (human) - STRING database

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ZNF177

Zinc finger protein 177; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family (481 aa)

Predicted Functional Partners:

ERVW-1

0.645

FSD1

0.573

C1orf115

0.528

DPYSL4

0.526

BYSL

0.511

SLC27A5

0.476

FYCO1

0.465

YIPF2

0.461

NKX2-3

0.455

AHCYL1

0.450

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AHCYL1	ZNF177	ENSP00000358814	ENSP00000468531	S-adenosylhomocysteine hydrolase-like protein 1; Multifaceted cellular regulator which coordinates several essential cellular functions including regulation of epithelial HCO3(-) and fluid secretion, mRNA processing and DNA replication. Regulates ITPR1 sensitivity to inositol 1,4,5- trisphosphate competing for the common binding site and acting as endogenous ’pseudoligand’ whose inhibitory activity can be modulated by its phosphorylation status. In the pancreatic and salivary ducts, at resting state, attenuates inositol 1,4,5- trisphosphate-induced calcium release by interacting with I [...]	Zinc finger protein 177; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family	0.450
BYSL	ZNF177	ENSP00000230340	ENSP00000468531	Bystin; Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits. May be required for trophinin-dependent regulation of cell adhesion during implantation of human embryos; Belongs to the bystin family	Zinc finger protein 177; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family	0.511
C1orf115	ZNF177	ENSP00000294889	ENSP00000468531	Uncharacterized protein C1orf115; Chromosome 1 open reading frame 115	Zinc finger protein 177; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family	0.528
DPYSL4	ZNF177	ENSP00000339850	ENSP00000468531	Dihydropyrimidinase-related protein 4; Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration (By similarity); Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family	Zinc finger protein 177; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family	0.526
ERVW-1	ZNF177	ENSP00000419945	ENSP00000468531	Syncytin-1; This endogenous retroviral envelope protein has retained its original fusogenic properties and participates in trophoblast fusion and the formation of a syncytium during placenta morphogenesis. May induce fusion through binding of SLC1A4 and SLC1A5	Zinc finger protein 177; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family	0.645
FSD1	ZNF177	ENSP00000221856	ENSP00000468531	Fibronectin type III and SPRY domain-containing protein 1; May be involved in microtubule organization and stabilization; Fibronectin type III domain containing	Zinc finger protein 177; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family	0.573
FYCO1	ZNF177	ENSP00000296137	ENSP00000468531	FYVE and coiled-coil domain-containing protein 1; May mediate microtubule plus end-directed vesicle transport; GOLD domain containing	Zinc finger protein 177; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family	0.465
NKX2-3	ZNF177	ENSP00000342828	ENSP00000468531	Homeobox protein Nkx-2.3; Transcription factor; NKL subclass homeoboxes and pseudogenes	Zinc finger protein 177; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family	0.455
SLC27A5	ZNF177	ENSP00000263093	ENSP00000468531	Bile acyl-CoA synthetase; Acyl-CoA synthetase involved in bile acid metabolism. Proposed to catalyze the first step in the conjugation of C24 bile acids (choloneates) to glycine and taurine before excretion into bile canaliculi by activating them to their CoA thioesters. Seems to activate secondary bile acids entering the liver from the enterohepatic circulation. In vitro, also activates 3-alpha,7- alpha,12-alpha-trihydroxy-5-beta-cholestanate (THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol; Belongs to the ATP-dependent AMP-binding enzyme family	Zinc finger protein 177; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family	0.476
YIPF2	ZNF177	ENSP00000253031	ENSP00000468531	Protein YIPF2; Yip1 domain family member 2	Zinc finger protein 177; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family	0.461
ZNF177	AHCYL1	ENSP00000468531	ENSP00000358814	Zinc finger protein 177; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family	S-adenosylhomocysteine hydrolase-like protein 1; Multifaceted cellular regulator which coordinates several essential cellular functions including regulation of epithelial HCO3(-) and fluid secretion, mRNA processing and DNA replication. Regulates ITPR1 sensitivity to inositol 1,4,5- trisphosphate competing for the common binding site and acting as endogenous ’pseudoligand’ whose inhibitory activity can be modulated by its phosphorylation status. In the pancreatic and salivary ducts, at resting state, attenuates inositol 1,4,5- trisphosphate-induced calcium release by interacting with I [...]	0.450
ZNF177	BYSL	ENSP00000468531	ENSP00000230340	Zinc finger protein 177; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family	Bystin; Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits. May be required for trophinin-dependent regulation of cell adhesion during implantation of human embryos; Belongs to the bystin family	0.511
ZNF177	C1orf115	ENSP00000468531	ENSP00000294889	Zinc finger protein 177; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family	Uncharacterized protein C1orf115; Chromosome 1 open reading frame 115	0.528
ZNF177	DPYSL4	ENSP00000468531	ENSP00000339850	Zinc finger protein 177; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family	Dihydropyrimidinase-related protein 4; Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration (By similarity); Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family	0.526
ZNF177	ERVW-1	ENSP00000468531	ENSP00000419945	Zinc finger protein 177; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family	Syncytin-1; This endogenous retroviral envelope protein has retained its original fusogenic properties and participates in trophoblast fusion and the formation of a syncytium during placenta morphogenesis. May induce fusion through binding of SLC1A4 and SLC1A5	0.645
ZNF177	FSD1	ENSP00000468531	ENSP00000221856	Zinc finger protein 177; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family	Fibronectin type III and SPRY domain-containing protein 1; May be involved in microtubule organization and stabilization; Fibronectin type III domain containing	0.573
ZNF177	FYCO1	ENSP00000468531	ENSP00000296137	Zinc finger protein 177; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family	FYVE and coiled-coil domain-containing protein 1; May mediate microtubule plus end-directed vesicle transport; GOLD domain containing	0.465
ZNF177	NKX2-3	ENSP00000468531	ENSP00000342828	Zinc finger protein 177; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family	Homeobox protein Nkx-2.3; Transcription factor; NKL subclass homeoboxes and pseudogenes	0.455
ZNF177	SLC27A5	ENSP00000468531	ENSP00000263093	Zinc finger protein 177; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family	Bile acyl-CoA synthetase; Acyl-CoA synthetase involved in bile acid metabolism. Proposed to catalyze the first step in the conjugation of C24 bile acids (choloneates) to glycine and taurine before excretion into bile canaliculi by activating them to their CoA thioesters. Seems to activate secondary bile acids entering the liver from the enterohepatic circulation. In vitro, also activates 3-alpha,7- alpha,12-alpha-trihydroxy-5-beta-cholestanate (THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol; Belongs to the ATP-dependent AMP-binding enzyme family	0.476
ZNF177	YIPF2	ENSP00000468531	ENSP00000253031	Zinc finger protein 177; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family	Protein YIPF2; Yip1 domain family member 2	0.461

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