node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CCDC134 | FSIP1 | ENSP00000255784 | ENSP00000280236 | Coiled-coil domain-containing protein 134; In extracellular secreted form, promotes proliferation and activation of CD8(+) T cells, suggesting a cytokine-like function. Enhances cytotoxic anti-tumor activity of CD8(+) T cells. May inhibit ERK and JNK signaling activity. May suppress cell migration and invasion activity, via its effects on ERK and JNK signaling; Belongs to the CCDC134 family | Fibrous sheath interacting protein 1; Belongs to the FSIP1 family | 0.507 |
CCDC134 | JRKL | ENSP00000255784 | ENSP00000333350 | Coiled-coil domain-containing protein 134; In extracellular secreted form, promotes proliferation and activation of CD8(+) T cells, suggesting a cytokine-like function. Enhances cytotoxic anti-tumor activity of CD8(+) T cells. May inhibit ERK and JNK signaling activity. May suppress cell migration and invasion activity, via its effects on ERK and JNK signaling; Belongs to the CCDC134 family | Jerky protein homolog-like; Helix-turn-helix CENPB type domain containing; Belongs to the tigger transposable element derived protein family | 0.553 |
CCDC134 | NUDCD1 | ENSP00000255784 | ENSP00000239690 | Coiled-coil domain-containing protein 134; In extracellular secreted form, promotes proliferation and activation of CD8(+) T cells, suggesting a cytokine-like function. Enhances cytotoxic anti-tumor activity of CD8(+) T cells. May inhibit ERK and JNK signaling activity. May suppress cell migration and invasion activity, via its effects on ERK and JNK signaling; Belongs to the CCDC134 family | NudC domain containing 1 | 0.531 |
CCDC134 | TXNL4B | ENSP00000255784 | ENSP00000268483 | Coiled-coil domain-containing protein 134; In extracellular secreted form, promotes proliferation and activation of CD8(+) T cells, suggesting a cytokine-like function. Enhances cytotoxic anti-tumor activity of CD8(+) T cells. May inhibit ERK and JNK signaling activity. May suppress cell migration and invasion activity, via its effects on ERK and JNK signaling; Belongs to the CCDC134 family | Thioredoxin-like protein 4B; Essential role in pre-mRNA splicing. Required in cell cycle progression for S/G(2) transition; Belongs to the DIM1 family | 0.510 |
CCDC134 | ZNF461 | ENSP00000255784 | ENSP00000467931 | Coiled-coil domain-containing protein 134; In extracellular secreted form, promotes proliferation and activation of CD8(+) T cells, suggesting a cytokine-like function. Enhances cytotoxic anti-tumor activity of CD8(+) T cells. May inhibit ERK and JNK signaling activity. May suppress cell migration and invasion activity, via its effects on ERK and JNK signaling; Belongs to the CCDC134 family | Zinc finger protein 461; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.580 |
DEPDC4 | HEATR4 | ENSP00000396234 | ENSP00000450444 | DEP domain containing 4 | HEAT repeat-containing protein 4; Armadillo-like helical domain containing | 0.671 |
DEPDC4 | ZNF461 | ENSP00000396234 | ENSP00000467931 | DEP domain containing 4 | Zinc finger protein 461; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.642 |
FSIP1 | CCDC134 | ENSP00000280236 | ENSP00000255784 | Fibrous sheath interacting protein 1; Belongs to the FSIP1 family | Coiled-coil domain-containing protein 134; In extracellular secreted form, promotes proliferation and activation of CD8(+) T cells, suggesting a cytokine-like function. Enhances cytotoxic anti-tumor activity of CD8(+) T cells. May inhibit ERK and JNK signaling activity. May suppress cell migration and invasion activity, via its effects on ERK and JNK signaling; Belongs to the CCDC134 family | 0.507 |
FSIP1 | JRKL | ENSP00000280236 | ENSP00000333350 | Fibrous sheath interacting protein 1; Belongs to the FSIP1 family | Jerky protein homolog-like; Helix-turn-helix CENPB type domain containing; Belongs to the tigger transposable element derived protein family | 0.532 |
FSIP1 | NUDCD1 | ENSP00000280236 | ENSP00000239690 | Fibrous sheath interacting protein 1; Belongs to the FSIP1 family | NudC domain containing 1 | 0.504 |
FSIP1 | TXNL4B | ENSP00000280236 | ENSP00000268483 | Fibrous sheath interacting protein 1; Belongs to the FSIP1 family | Thioredoxin-like protein 4B; Essential role in pre-mRNA splicing. Required in cell cycle progression for S/G(2) transition; Belongs to the DIM1 family | 0.490 |
FSIP1 | ZNF461 | ENSP00000280236 | ENSP00000467931 | Fibrous sheath interacting protein 1; Belongs to the FSIP1 family | Zinc finger protein 461; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.548 |
HEATR4 | DEPDC4 | ENSP00000450444 | ENSP00000396234 | HEAT repeat-containing protein 4; Armadillo-like helical domain containing | DEP domain containing 4 | 0.671 |
HEATR4 | ZNF461 | ENSP00000450444 | ENSP00000467931 | HEAT repeat-containing protein 4; Armadillo-like helical domain containing | Zinc finger protein 461; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.558 |
JRKL | CCDC134 | ENSP00000333350 | ENSP00000255784 | Jerky protein homolog-like; Helix-turn-helix CENPB type domain containing; Belongs to the tigger transposable element derived protein family | Coiled-coil domain-containing protein 134; In extracellular secreted form, promotes proliferation and activation of CD8(+) T cells, suggesting a cytokine-like function. Enhances cytotoxic anti-tumor activity of CD8(+) T cells. May inhibit ERK and JNK signaling activity. May suppress cell migration and invasion activity, via its effects on ERK and JNK signaling; Belongs to the CCDC134 family | 0.553 |
JRKL | FSIP1 | ENSP00000333350 | ENSP00000280236 | Jerky protein homolog-like; Helix-turn-helix CENPB type domain containing; Belongs to the tigger transposable element derived protein family | Fibrous sheath interacting protein 1; Belongs to the FSIP1 family | 0.532 |
JRKL | NUDCD1 | ENSP00000333350 | ENSP00000239690 | Jerky protein homolog-like; Helix-turn-helix CENPB type domain containing; Belongs to the tigger transposable element derived protein family | NudC domain containing 1 | 0.553 |
JRKL | TXNL4B | ENSP00000333350 | ENSP00000268483 | Jerky protein homolog-like; Helix-turn-helix CENPB type domain containing; Belongs to the tigger transposable element derived protein family | Thioredoxin-like protein 4B; Essential role in pre-mRNA splicing. Required in cell cycle progression for S/G(2) transition; Belongs to the DIM1 family | 0.540 |
JRKL | ZNF461 | ENSP00000333350 | ENSP00000467931 | Jerky protein homolog-like; Helix-turn-helix CENPB type domain containing; Belongs to the tigger transposable element derived protein family | Zinc finger protein 461; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.576 |
NUDCD1 | CCDC134 | ENSP00000239690 | ENSP00000255784 | NudC domain containing 1 | Coiled-coil domain-containing protein 134; In extracellular secreted form, promotes proliferation and activation of CD8(+) T cells, suggesting a cytokine-like function. Enhances cytotoxic anti-tumor activity of CD8(+) T cells. May inhibit ERK and JNK signaling activity. May suppress cell migration and invasion activity, via its effects on ERK and JNK signaling; Belongs to the CCDC134 family | 0.531 |