node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABCA8 | ABCC8 | ENSP00000467271 | ENSP00000303960 | ATP-binding cassette sub-family A member 8; ATP-dependent lipophilic drug transporter; ATP binding cassette subfamily A | ATP-binding cassette sub-family C member 8; Subunit of the beta-cell ATP-sensitive potassium channel (KATP). Regulator of ATP-sensitive K(+) channels and insulin release; ATP binding cassette subfamily C | 0.468 |
ABCA8 | ABCC9 | ENSP00000467271 | ENSP00000261200 | ATP-binding cassette sub-family A member 8; ATP-dependent lipophilic drug transporter; ATP binding cassette subfamily A | ATP-binding cassette sub-family C member 9; Subunit of ATP-sensitive potassium channels (KATP). Can form cardiac and smooth muscle-type KATP channels with KCNJ11. KCNJ11 forms the channel pore while ABCC9 is required for activation and regulation; Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily | 0.577 |
ABCA8 | ABCF1 | ENSP00000467271 | ENSP00000313603 | ATP-binding cassette sub-family A member 8; ATP-dependent lipophilic drug transporter; ATP binding cassette subfamily A | ATP-binding cassette sub-family F member 1; Isoform 2 is required for efficient Cap- and IRES- mediated mRNA translation initiation. Isoform 2 is not involved in the ribosome biogenesis; ATP binding cassette subfamily F | 0.474 |
ABCA8 | ABCF3 | ENSP00000467271 | ENSP00000411471 | ATP-binding cassette sub-family A member 8; ATP-dependent lipophilic drug transporter; ATP binding cassette subfamily A | ATP-binding cassette sub-family F member 3; Displays an antiviral effect against flaviviruses such as west Nile virus (WNV) in the presence of OAS1B; ATP binding cassette subfamily F | 0.542 |
ABCA8 | ASXL3 | ENSP00000467271 | ENSP00000269197 | ATP-binding cassette sub-family A member 8; ATP-dependent lipophilic drug transporter; ATP binding cassette subfamily A | Putative Polycomb group protein ASXL3; Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They probably act via methylation of histones, rendering chromatin heritably changed in its expressibility (By similarity) | 0.447 |
ABCA8 | CBLN2 | ENSP00000467271 | ENSP00000269503 | ATP-binding cassette sub-family A member 8; ATP-dependent lipophilic drug transporter; ATP binding cassette subfamily A | Cerebellin-2; May play role in synaptogenesis induction | 0.668 |
ABCA8 | OSBPL7 | ENSP00000467271 | ENSP00000007414 | ATP-binding cassette sub-family A member 8; ATP-dependent lipophilic drug transporter; ATP binding cassette subfamily A | Oxysterol-binding protein-related protein 7; Pleckstrin homology domain containing; Belongs to the OSBP family | 0.543 |
ABCA8 | SLC22A8 | ENSP00000467271 | ENSP00000337335 | ATP-binding cassette sub-family A member 8; ATP-dependent lipophilic drug transporter; ATP binding cassette subfamily A | Solute carrier family 22 member 8; Plays an important role in the excretion/detoxification of endogenous and exogenous organic anions, especially from the brain and kidney. Involved in the transport basolateral of steviol, fexofenadine. Transports benzylpenicillin (PCG), estrone- 3-sulfate (E1S), cimetidine (CMD), 2,4-dichloro-phenoxyacetate (2,4-D), p-amino-hippurate (PAH), acyclovir (ACV) and ochratoxin (OTA); Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family | 0.792 |
ABCA8 | SRRM1 | ENSP00000467271 | ENSP00000326261 | ATP-binding cassette sub-family A member 8; ATP-dependent lipophilic drug transporter; ATP binding cassette subfamily A | Serine/arginine repetitive matrix protein 1; Part of pre- and post-splicing multiprotein mRNP complexes. Involved in numerous pre-mRNA processing events. Promotes constitutive and exonic splicing enhancer (ESE)-dependent splicing activation by bridging together sequence-specific (SR family proteins, SFRS4, SFRS5 and TRA2B/SFRS10) and basal snRNP (SNRP70 and SNRPA1) factors of the spliceosome. Stimulates mRNA 3’-end cleavage independently of the formation of an exon junction complex. Binds both pre-mRNA and spliced mRNA 20-25 nt upstream of exon-exon junctions. Binds RNA and DNA with lo [...] | 0.582 |
ABCA8 | TYW1B | ENSP00000467271 | ENSP00000482502 | ATP-binding cassette sub-family A member 8; ATP-dependent lipophilic drug transporter; ATP binding cassette subfamily A | S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase; Probable component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3’-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the condensation of N- methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine, an intermediate in wybutosine biosynthesis (By similarity) | 0.567 |
ABCC8 | ABCA8 | ENSP00000303960 | ENSP00000467271 | ATP-binding cassette sub-family C member 8; Subunit of the beta-cell ATP-sensitive potassium channel (KATP). Regulator of ATP-sensitive K(+) channels and insulin release; ATP binding cassette subfamily C | ATP-binding cassette sub-family A member 8; ATP-dependent lipophilic drug transporter; ATP binding cassette subfamily A | 0.468 |
ABCC8 | ABCC9 | ENSP00000303960 | ENSP00000261200 | ATP-binding cassette sub-family C member 8; Subunit of the beta-cell ATP-sensitive potassium channel (KATP). Regulator of ATP-sensitive K(+) channels and insulin release; ATP binding cassette subfamily C | ATP-binding cassette sub-family C member 9; Subunit of ATP-sensitive potassium channels (KATP). Can form cardiac and smooth muscle-type KATP channels with KCNJ11. KCNJ11 forms the channel pore while ABCC9 is required for activation and regulation; Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily | 0.727 |
ABCC8 | ABCF1 | ENSP00000303960 | ENSP00000313603 | ATP-binding cassette sub-family C member 8; Subunit of the beta-cell ATP-sensitive potassium channel (KATP). Regulator of ATP-sensitive K(+) channels and insulin release; ATP binding cassette subfamily C | ATP-binding cassette sub-family F member 1; Isoform 2 is required for efficient Cap- and IRES- mediated mRNA translation initiation. Isoform 2 is not involved in the ribosome biogenesis; ATP binding cassette subfamily F | 0.451 |
ABCC8 | ABCF3 | ENSP00000303960 | ENSP00000411471 | ATP-binding cassette sub-family C member 8; Subunit of the beta-cell ATP-sensitive potassium channel (KATP). Regulator of ATP-sensitive K(+) channels and insulin release; ATP binding cassette subfamily C | ATP-binding cassette sub-family F member 3; Displays an antiviral effect against flaviviruses such as west Nile virus (WNV) in the presence of OAS1B; ATP binding cassette subfamily F | 0.445 |
ABCC9 | ABCA8 | ENSP00000261200 | ENSP00000467271 | ATP-binding cassette sub-family C member 9; Subunit of ATP-sensitive potassium channels (KATP). Can form cardiac and smooth muscle-type KATP channels with KCNJ11. KCNJ11 forms the channel pore while ABCC9 is required for activation and regulation; Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily | ATP-binding cassette sub-family A member 8; ATP-dependent lipophilic drug transporter; ATP binding cassette subfamily A | 0.577 |
ABCC9 | ABCC8 | ENSP00000261200 | ENSP00000303960 | ATP-binding cassette sub-family C member 9; Subunit of ATP-sensitive potassium channels (KATP). Can form cardiac and smooth muscle-type KATP channels with KCNJ11. KCNJ11 forms the channel pore while ABCC9 is required for activation and regulation; Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily | ATP-binding cassette sub-family C member 8; Subunit of the beta-cell ATP-sensitive potassium channel (KATP). Regulator of ATP-sensitive K(+) channels and insulin release; ATP binding cassette subfamily C | 0.727 |
ABCC9 | ABCF1 | ENSP00000261200 | ENSP00000313603 | ATP-binding cassette sub-family C member 9; Subunit of ATP-sensitive potassium channels (KATP). Can form cardiac and smooth muscle-type KATP channels with KCNJ11. KCNJ11 forms the channel pore while ABCC9 is required for activation and regulation; Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily | ATP-binding cassette sub-family F member 1; Isoform 2 is required for efficient Cap- and IRES- mediated mRNA translation initiation. Isoform 2 is not involved in the ribosome biogenesis; ATP binding cassette subfamily F | 0.489 |
ABCC9 | ABCF3 | ENSP00000261200 | ENSP00000411471 | ATP-binding cassette sub-family C member 9; Subunit of ATP-sensitive potassium channels (KATP). Can form cardiac and smooth muscle-type KATP channels with KCNJ11. KCNJ11 forms the channel pore while ABCC9 is required for activation and regulation; Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily | ATP-binding cassette sub-family F member 3; Displays an antiviral effect against flaviviruses such as west Nile virus (WNV) in the presence of OAS1B; ATP binding cassette subfamily F | 0.525 |
ABCF1 | ABCA8 | ENSP00000313603 | ENSP00000467271 | ATP-binding cassette sub-family F member 1; Isoform 2 is required for efficient Cap- and IRES- mediated mRNA translation initiation. Isoform 2 is not involved in the ribosome biogenesis; ATP binding cassette subfamily F | ATP-binding cassette sub-family A member 8; ATP-dependent lipophilic drug transporter; ATP binding cassette subfamily A | 0.474 |
ABCF1 | ABCC8 | ENSP00000313603 | ENSP00000303960 | ATP-binding cassette sub-family F member 1; Isoform 2 is required for efficient Cap- and IRES- mediated mRNA translation initiation. Isoform 2 is not involved in the ribosome biogenesis; ATP binding cassette subfamily F | ATP-binding cassette sub-family C member 8; Subunit of the beta-cell ATP-sensitive potassium channel (KATP). Regulator of ATP-sensitive K(+) channels and insulin release; ATP binding cassette subfamily C | 0.451 |