ZNF570 protein (human) - STRING database

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ZNF570

Zinc finger protein 570; May be involved in transcriptional regulation; Zinc fingers C2H2-type (592 aa)

Predicted Functional Partners:

TRIM28

0.903

NUDCD2

0.652

C14orf177

0.640

SMTNL2

0.566

KRCC1

0.561

LMNB2

0.473

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C14orf177	NUDCD2	ENSP00000321360	ENSP00000304854	Putative uncharacterized protein C14orf177; Chromosome 14 open reading frame 177	NudC domain-containing protein 2; May regulate the LIS1/dynein pathway by stabilizing LIS1 with Hsp90 chaperone; NudC family	0.552
C14orf177	ZNF570	ENSP00000321360	ENSP00000467218	Putative uncharacterized protein C14orf177; Chromosome 14 open reading frame 177	Zinc finger protein 570; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.640
KRCC1	LMNB2	ENSP00000340083	ENSP00000327054	Lysine rich coiled-coil 1	Lamin-B2; Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin; Belongs to the intermediate filament family	0.452
KRCC1	SMTNL2	ENSP00000340083	ENSP00000373964	Lysine rich coiled-coil 1	Smoothelin-like protein 2; Smoothelin like 2	0.770
KRCC1	ZNF570	ENSP00000340083	ENSP00000467218	Lysine rich coiled-coil 1	Zinc finger protein 570; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.561
LMNB2	KRCC1	ENSP00000327054	ENSP00000340083	Lamin-B2; Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin; Belongs to the intermediate filament family	Lysine rich coiled-coil 1	0.452
LMNB2	SMTNL2	ENSP00000327054	ENSP00000373964	Lamin-B2; Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin; Belongs to the intermediate filament family	Smoothelin-like protein 2; Smoothelin like 2	0.495
LMNB2	ZNF570	ENSP00000327054	ENSP00000467218	Lamin-B2; Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin; Belongs to the intermediate filament family	Zinc finger protein 570; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.473
NUDCD2	C14orf177	ENSP00000304854	ENSP00000321360	NudC domain-containing protein 2; May regulate the LIS1/dynein pathway by stabilizing LIS1 with Hsp90 chaperone; NudC family	Putative uncharacterized protein C14orf177; Chromosome 14 open reading frame 177	0.552
NUDCD2	ZNF570	ENSP00000304854	ENSP00000467218	NudC domain-containing protein 2; May regulate the LIS1/dynein pathway by stabilizing LIS1 with Hsp90 chaperone; NudC family	Zinc finger protein 570; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.652
SMTNL2	KRCC1	ENSP00000373964	ENSP00000340083	Smoothelin-like protein 2; Smoothelin like 2	Lysine rich coiled-coil 1	0.770
SMTNL2	LMNB2	ENSP00000373964	ENSP00000327054	Smoothelin-like protein 2; Smoothelin like 2	Lamin-B2; Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin; Belongs to the intermediate filament family	0.495
SMTNL2	ZNF570	ENSP00000373964	ENSP00000467218	Smoothelin-like protein 2; Smoothelin like 2	Zinc finger protein 570; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.566
TRIM28	ZNF570	ENSP00000253024	ENSP00000467218	Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at ’Lys-9’ (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 ’Lys-9 and ’Lys-14’ acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...]	Zinc finger protein 570; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.903
ZNF570	C14orf177	ENSP00000467218	ENSP00000321360	Zinc finger protein 570; May be involved in transcriptional regulation; Zinc fingers C2H2-type	Putative uncharacterized protein C14orf177; Chromosome 14 open reading frame 177	0.640
ZNF570	KRCC1	ENSP00000467218	ENSP00000340083	Zinc finger protein 570; May be involved in transcriptional regulation; Zinc fingers C2H2-type	Lysine rich coiled-coil 1	0.561
ZNF570	LMNB2	ENSP00000467218	ENSP00000327054	Zinc finger protein 570; May be involved in transcriptional regulation; Zinc fingers C2H2-type	Lamin-B2; Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin; Belongs to the intermediate filament family	0.473
ZNF570	NUDCD2	ENSP00000467218	ENSP00000304854	Zinc finger protein 570; May be involved in transcriptional regulation; Zinc fingers C2H2-type	NudC domain-containing protein 2; May regulate the LIS1/dynein pathway by stabilizing LIS1 with Hsp90 chaperone; NudC family	0.652
ZNF570	SMTNL2	ENSP00000467218	ENSP00000373964	Zinc finger protein 570; May be involved in transcriptional regulation; Zinc fingers C2H2-type	Smoothelin-like protein 2; Smoothelin like 2	0.566
ZNF570	TRIM28	ENSP00000467218	ENSP00000253024	Zinc finger protein 570; May be involved in transcriptional regulation; Zinc fingers C2H2-type	Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at ’Lys-9’ (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 ’Lys-9 and ’Lys-14’ acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...]	0.903

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