• Version:
  • 11.0 [archived version]
STRINGSTRING
SNX32 SNX32 PRODH2 PRODH2 OVOL3 OVOL3 TMEM132E TMEM132E TMEM171 TMEM171 TMEM150C TMEM150C TMEM211 TMEM211 GPR137C GPR137C GPR162 GPR162 TMEM212 TMEM212 TMEM221 TMEM221
"OVOL3" - Putative transcription factor ovo-like protein 3 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OVOL3Putative transcription factor ovo-like protein 3; May act as a transcription regulator (214 aa)    
Predicted Functional Partners:
TMEM221
Transmembrane protein 221 (291 aa)
           
  0.621
TMEM212
Transmembrane protein 212 (194 aa)
           
  0.594
TMEM211
Transmembrane protein 211 (129 aa)
           
  0.581
GPR137C
Integral membrane protein GPR137C; G protein-coupled receptor 137C (429 aa)
           
  0.574
TMEM132E
Transmembrane protein 132E; Required for normal inner ear hair cell function and hearing; Belongs to the TMEM132 family (984 aa)
           
  0.566
TMEM171
Transmembrane protein 171 (324 aa)
           
  0.550
TMEM150C
Transmembrane protein 150C; Component of a mechanosensitive cation channel. Confers mechanically activated (MA) currents with slow inactivation kinetics. May contribute to proprioception; Belongs to the DRAM/TMEM150 family (249 aa)
           
  0.543
PRODH2
Hydroxyproline dehydrogenase; Dehydrogenase that converts trans-4-L-hydroxyproline to delta-1-pyrroline-3-hydroxy-5-carboxylate (Hyp) using ubiquinone- 10 as the terminal electron acceptor. Can also use proline as a substrate but with a very much lower efficiency. Does not react with other diastereomers of Hyp- trans-4-D-hydroxyproline and cis- 4-L-hydroxyproline. Ubiquininone analogs such as menadione, duroquinone and ubiquinone-1 react more efficiently than oxygen as the terminal electron acceptor during catalysis (536 aa)
           
  0.540
SNX32
Sorting nexin-32; May be involved in several stages of intracellular trafficking; PX-BAR domain containing (403 aa)
           
  0.527
GPR162
Probable G-protein coupled receptor 162; Orphan receptor; G protein-coupled receptors, Class A orphans (588 aa)
           
  0.519
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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