C19orf53 protein (human) - STRING database

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C19orf53

Leydig cell tumor 10 kDa protein homolog; May have a potential role in hypercalcemia of malignancy (99 aa)

Predicted Functional Partners:

C19orf67

0.676

C19orf57

0.647

FAM96B

0.639

NDUFB7

0.623

DCAF15

0.611

PODNL1

0.559

WDR83OS

0.550

ZSWIM4

0.539

ZNHIT1

0.533

C19orf66

0.530

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C19orf53	C19orf57	ENSP00000465432	ENSP00000254336	Leydig cell tumor 10 kDa protein homolog; May have a potential role in hypercalcemia of malignancy	Uncharacterized protein C19orf57; Chromosome 19 open reading frame 57	0.647
C19orf53	C19orf66	ENSP00000465432	ENSP00000253110	Leydig cell tumor 10 kDa protein homolog; May have a potential role in hypercalcemia of malignancy	Repressor of yield of DENV protein; Exhibits antiviral activity against dengue virus (DENV) and can inhibit the replication of all DENV serotypes. May block the protein translation of DENV RNA via its association with cellular mRNA-binding proteins and viral RNA. Can also limit the replication of hepatitis C virus (HCV), West Nile virus (WNV), Chikungunya virus (CHIKV), herpes simplex virus type 1 (HHV-1) and human adenovirus; Belongs to the RyDEN family	0.530
C19orf53	C19orf67	ENSP00000465432	ENSP00000449137	Leydig cell tumor 10 kDa protein homolog; May have a potential role in hypercalcemia of malignancy	UPF0575 protein C19orf67; Chromosome 19 open reading frame 67; Belongs to the UPF0575 family	0.676
C19orf53	DCAF15	ENSP00000465432	ENSP00000254337	Leydig cell tumor 10 kDa protein homolog; May have a potential role in hypercalcemia of malignancy	DDB1- and CUL4-associated factor 15; May be involved in ubiquitination and degradation through a DBB1-CUL4 E3 protein-ubiquitin ligase; DDB1 and CUL4 associated factors	0.611
C19orf53	FAM96B	ENSP00000465432	ENSP00000387471	Leydig cell tumor 10 kDa protein homolog; May have a potential role in hypercalcemia of malignancy	Mitotic spindle-associated MMXD complex subunit MIP18; Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. As part of the mitotic spindle-associated MMXD complex it plays a role in chromosome segregation, probably by facilitating iron-sulfur cluster assembly into ERCC2/XPD; Belongs to the MIP18 family	0.639
C19orf53	NDUFB7	ENSP00000465432	ENSP00000215565	Leydig cell tumor 10 kDa protein homolog; May have a potential role in hypercalcemia of malignancy	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone	0.623
C19orf53	PODNL1	ENSP00000465432	ENSP00000345175	Leydig cell tumor 10 kDa protein homolog; May have a potential role in hypercalcemia of malignancy	Podocan-like protein 1; Podocan like 1	0.559
C19orf53	WDR83OS	ENSP00000465432	ENSP00000468969	Leydig cell tumor 10 kDa protein homolog; May have a potential role in hypercalcemia of malignancy	Protein Asterix; WD repeat domain 83 opposite strand	0.550
C19orf53	ZNHIT1	ENSP00000465432	ENSP00000304593	Leydig cell tumor 10 kDa protein homolog; May have a potential role in hypercalcemia of malignancy	Zinc finger HIT domain-containing protein 1; Seems to play a role in p53-mediated apoptosis induction. Binds to NR1D2 and relieves it of its inhibitory effect on the transcription of APOC3 without affecting its DNA-binding activity; Belongs to the ZNHIT1 family	0.533
C19orf53	ZSWIM4	ENSP00000465432	ENSP00000254323	Leydig cell tumor 10 kDa protein homolog; May have a potential role in hypercalcemia of malignancy	Zinc finger SWIM-type containing 4	0.539
C19orf57	C19orf53	ENSP00000254336	ENSP00000465432	Uncharacterized protein C19orf57; Chromosome 19 open reading frame 57	Leydig cell tumor 10 kDa protein homolog; May have a potential role in hypercalcemia of malignancy	0.647
C19orf57	C19orf67	ENSP00000254336	ENSP00000449137	Uncharacterized protein C19orf57; Chromosome 19 open reading frame 57	UPF0575 protein C19orf67; Chromosome 19 open reading frame 67; Belongs to the UPF0575 family	0.700
C19orf57	DCAF15	ENSP00000254336	ENSP00000254337	Uncharacterized protein C19orf57; Chromosome 19 open reading frame 57	DDB1- and CUL4-associated factor 15; May be involved in ubiquitination and degradation through a DBB1-CUL4 E3 protein-ubiquitin ligase; DDB1 and CUL4 associated factors	0.582
C19orf57	NDUFB7	ENSP00000254336	ENSP00000215565	Uncharacterized protein C19orf57; Chromosome 19 open reading frame 57	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone	0.400
C19orf57	PODNL1	ENSP00000254336	ENSP00000345175	Uncharacterized protein C19orf57; Chromosome 19 open reading frame 57	Podocan-like protein 1; Podocan like 1	0.665
C19orf57	ZSWIM4	ENSP00000254336	ENSP00000254323	Uncharacterized protein C19orf57; Chromosome 19 open reading frame 57	Zinc finger SWIM-type containing 4	0.554
C19orf66	C19orf53	ENSP00000253110	ENSP00000465432	Repressor of yield of DENV protein; Exhibits antiviral activity against dengue virus (DENV) and can inhibit the replication of all DENV serotypes. May block the protein translation of DENV RNA via its association with cellular mRNA-binding proteins and viral RNA. Can also limit the replication of hepatitis C virus (HCV), West Nile virus (WNV), Chikungunya virus (CHIKV), herpes simplex virus type 1 (HHV-1) and human adenovirus; Belongs to the RyDEN family	Leydig cell tumor 10 kDa protein homolog; May have a potential role in hypercalcemia of malignancy	0.530
C19orf67	C19orf53	ENSP00000449137	ENSP00000465432	UPF0575 protein C19orf67; Chromosome 19 open reading frame 67; Belongs to the UPF0575 family	Leydig cell tumor 10 kDa protein homolog; May have a potential role in hypercalcemia of malignancy	0.676
C19orf67	C19orf57	ENSP00000449137	ENSP00000254336	UPF0575 protein C19orf67; Chromosome 19 open reading frame 67; Belongs to the UPF0575 family	Uncharacterized protein C19orf57; Chromosome 19 open reading frame 57	0.700
C19orf67	DCAF15	ENSP00000449137	ENSP00000254337	UPF0575 protein C19orf67; Chromosome 19 open reading frame 67; Belongs to the UPF0575 family	DDB1- and CUL4-associated factor 15; May be involved in ubiquitination and degradation through a DBB1-CUL4 E3 protein-ubiquitin ligase; DDB1 and CUL4 associated factors	0.669

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