• Version:
  • 11.0 [archived version]
STRINGSTRING
MAPK1IP1L MAPK1IP1L ANKEF1 ANKEF1 SLC27A3 SLC27A3 TRIM28 TRIM28 ZNF226 ZNF226 TMEM184A TMEM184A C17orf62 C17orf62 ANKMY1 ANKMY1 TSPYL4 TSPYL4 KIAA1644 KIAA1644 IGFLR1 IGFLR1
"ZNF226" - Zinc finger protein 226 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZNF226Zinc finger protein 226; May be involved in transcriptional regulation; Zinc fingers C2H2-type (803 aa)    
Predicted Functional Partners:
TRIM28
Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at ’Lys-9’ (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 ’Lys-9 and ’Lys-14’ acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] (835 aa)
     
    0.903
KIAA1644
Uncharacterized protein KIAA1644; KIAA1644 (199 aa)
           
  0.548
TMEM184A
Transmembrane protein 184A; Acts as a heparin receptor in vascular cells (By similarity). May be involved in vesicle transport in exocrine cells and Sertoli cells (By similarity) (413 aa)
           
  0.532
SLC27A3
Long-chain fatty acid transport protein 3; Has acyl-CoA ligase activity for long-chain and very- long-chain fatty acids. Does not exhibit fatty acid transport activity (By similarity); Acyl-CoA synthetase family (730 aa)
           
  0.521
ANKEF1
Ankyrin repeat and EF-hand domain containing 1 (776 aa)
     
 
  0.518
MAPK1IP1L
MAPK-interacting and spindle-stabilizing protein-like; Mitogen-activated protein kinase 1 interacting protein 1 like (245 aa)
           
  0.516
TSPYL4
Testis-specific Y-encoded-like protein 4; TSPY like 4 (414 aa)
       
 
  0.514
ANKMY1
Ankyrin repeat and MYND domain containing 1 (1030 aa)
           
  0.504
IGFLR1
IGF-like family receptor 1; Probable cell membrane receptor for the IGF-like family proteins. Binds IGFL1 and IGFL3 with a higher affinity. May also bind IGFL2 (355 aa)
           
  0.450
C17orf62
Uncharacterized protein C17orf62; Chromosome 17 open reading frame 62 (187 aa)
           
  0.441
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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