• Version:
  • 11.0 [archived version]
STRINGSTRING
UBASH3B UBASH3B COL28A1 COL28A1 HAPLN3 HAPLN3 TMEM88 TMEM88 LPPR1 LPPR1 GREB1L GREB1L FAM131B FAM131B DDX55 DDX55 ZMYM6 ZMYM6 TENM4 TENM4 MFAP2 MFAP2
"GREB1L" - GREB1-like protein in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GREB1LGREB1-like protein; Growth regulation by estrogen in breast cancer 1 like; Belongs to the GREB1 family (1923 aa)    
Predicted Functional Partners:
ZMYM6
Zinc finger MYM-type protein 6; Plays a role in the regulation of cell morphology and cytoskeletal organization; Zinc fingers MYM-type (1325 aa)
           
  0.680
HAPLN3
Hyaluronan and proteoglycan link protein 3; May function in hyaluronic acid binding; V-set domain containing (360 aa)
           
  0.552
DDX55
ATP-dependent RNA helicase DDX55; Probable ATP-binding RNA helicase; DEAD-box helicases (600 aa)
           
  0.551
TMEM88
Transmembrane protein 88; Inhibits the Wnt/beta-catenin signaling pathway. Crucial for heart development and acts downstream of GATA factors in the pre-cardiac mesoderm to specify lineage commitment of cardiomyocyte development (159 aa)
           
  0.539
FAM131B
Protein FAM131B; Family with sequence similarity 131 member B; Belongs to the FAM131 family (360 aa)
           
  0.535
TENM4
Teneurin-4; Involved in neural development, regulating the establishment of proper connectivity within the nervous system. Plays a role in the establishment of the anterior-posterior axis during gastrulation. Regulates the differentiation and cellular process formation of oligodendrocytes and myelination of small- diameter axons in the central nervous system (CNS). Promotes activation of focal adhesion kinase. May function as a cellular signal transducer (By similarity); Belongs to the tenascin family. Teneurin subfamily (2769 aa)
           
  0.530
MFAP2
Microfibrillar-associated protein 2; Component of the elastin-associated microfibrils; Belongs to the MFAP family (183 aa)
           
  0.519
COL28A1
Collagen alpha-1(XXVIII) chain; May act as a cell-binding protein; Belongs to the VWA-containing collagen family (1125 aa)
           
  0.505
LPPR1
Lipid phosphate phosphatase-related protein type 1 (325 aa)
           
  0.499
UBASH3B
Ubiquitin-associated and SH3 domain-containing protein B; Interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. Promotes accumulation of activated target receptors, such as T-cell receptors and EGFR, on the cell surface. Exhibits tyrosine phosphatase activity toward several substrates including EGFR, FAK, SYK, and ZAP70. Down-regulates proteins that are dually modified by both protein tyrosine phosphorylation and ubiquitination (649 aa)
           
  0.493
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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