TMEM98 protein (human) - STRING database

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

TMEM98

Transmembrane protein 98 (226 aa)

Predicted Functional Partners:

ATP1B3

0.787

TMEM176A

0.721

MYBPHL

0.699

CAPN7

0.574

FAM19A2

0.549

MYO1D

0.522

CCDC64

0.518

TMEM9B

0.516

LDOC1L

0.512

XKRX

0.509

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but resolution at 400 dpi

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as simple tabular text output:

download

TSV: tab separated values - can be opened in Excel

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATP1B3	TMEM98	ENSP00000286371	ENSP00000463245	Sodium/potassium-transporting ATPase subunit beta-3; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-3 subunit is not known; ATPase Na+/K+ transporting subunits	Transmembrane protein 98	0.787
CAPN7	TMEM98	ENSP00000253693	ENSP00000463245	Calpain-7; Calcium-regulated non-lysosomal thiol-protease; Belongs to the peptidase C2 family	Transmembrane protein 98	0.574
CCDC64	FAM19A2	ENSP00000380690	ENSP00000393987	BICD family-like cargo adapter 1; Component of secretory vesicle machinery in developing neurons that acts as a regulator of neurite outgrowth. Regulates the secretory vesicle transport by controlling the accumulation of Rab6-containing secretory vesicles in the pericentrosomal region restricting anterograde secretory transport during the early phase of neuronal differentiation, thereby inhibiting neuritogenesis (By similarity); Belongs to the BICDR family	Protein FAM19A2; Family with sequence similarity 19 member A2, C-C motif chemokine like	0.591
CCDC64	LDOC1L	ENSP00000380690	ENSP00000340434	BICD family-like cargo adapter 1; Component of secretory vesicle machinery in developing neurons that acts as a regulator of neurite outgrowth. Regulates the secretory vesicle transport by controlling the accumulation of Rab6-containing secretory vesicles in the pericentrosomal region restricting anterograde secretory transport during the early phase of neuronal differentiation, thereby inhibiting neuritogenesis (By similarity); Belongs to the BICDR family	Retrotransposon Gag-like protein 6; Leucine zipper, down-regulated in cancer 1-like	0.539
CCDC64	TMEM98	ENSP00000380690	ENSP00000463245	BICD family-like cargo adapter 1; Component of secretory vesicle machinery in developing neurons that acts as a regulator of neurite outgrowth. Regulates the secretory vesicle transport by controlling the accumulation of Rab6-containing secretory vesicles in the pericentrosomal region restricting anterograde secretory transport during the early phase of neuronal differentiation, thereby inhibiting neuritogenesis (By similarity); Belongs to the BICDR family	Transmembrane protein 98	0.518
CCDC64	XKRX	ENSP00000380690	ENSP00000362047	BICD family-like cargo adapter 1; Component of secretory vesicle machinery in developing neurons that acts as a regulator of neurite outgrowth. Regulates the secretory vesicle transport by controlling the accumulation of Rab6-containing secretory vesicles in the pericentrosomal region restricting anterograde secretory transport during the early phase of neuronal differentiation, thereby inhibiting neuritogenesis (By similarity); Belongs to the BICDR family	XK-related protein 2; XK related, X-linked	0.618
FAM19A2	CCDC64	ENSP00000393987	ENSP00000380690	Protein FAM19A2; Family with sequence similarity 19 member A2, C-C motif chemokine like	BICD family-like cargo adapter 1; Component of secretory vesicle machinery in developing neurons that acts as a regulator of neurite outgrowth. Regulates the secretory vesicle transport by controlling the accumulation of Rab6-containing secretory vesicles in the pericentrosomal region restricting anterograde secretory transport during the early phase of neuronal differentiation, thereby inhibiting neuritogenesis (By similarity); Belongs to the BICDR family	0.591
FAM19A2	LDOC1L	ENSP00000393987	ENSP00000340434	Protein FAM19A2; Family with sequence similarity 19 member A2, C-C motif chemokine like	Retrotransposon Gag-like protein 6; Leucine zipper, down-regulated in cancer 1-like	0.560
FAM19A2	TMEM98	ENSP00000393987	ENSP00000463245	Protein FAM19A2; Family with sequence similarity 19 member A2, C-C motif chemokine like	Transmembrane protein 98	0.549
FAM19A2	XKRX	ENSP00000393987	ENSP00000362047	Protein FAM19A2; Family with sequence similarity 19 member A2, C-C motif chemokine like	XK-related protein 2; XK related, X-linked	0.619
LDOC1L	CCDC64	ENSP00000340434	ENSP00000380690	Retrotransposon Gag-like protein 6; Leucine zipper, down-regulated in cancer 1-like	BICD family-like cargo adapter 1; Component of secretory vesicle machinery in developing neurons that acts as a regulator of neurite outgrowth. Regulates the secretory vesicle transport by controlling the accumulation of Rab6-containing secretory vesicles in the pericentrosomal region restricting anterograde secretory transport during the early phase of neuronal differentiation, thereby inhibiting neuritogenesis (By similarity); Belongs to the BICDR family	0.539
LDOC1L	FAM19A2	ENSP00000340434	ENSP00000393987	Retrotransposon Gag-like protein 6; Leucine zipper, down-regulated in cancer 1-like	Protein FAM19A2; Family with sequence similarity 19 member A2, C-C motif chemokine like	0.560
LDOC1L	TMEM98	ENSP00000340434	ENSP00000463245	Retrotransposon Gag-like protein 6; Leucine zipper, down-regulated in cancer 1-like	Transmembrane protein 98	0.512
LDOC1L	XKRX	ENSP00000340434	ENSP00000362047	Retrotransposon Gag-like protein 6; Leucine zipper, down-regulated in cancer 1-like	XK-related protein 2; XK related, X-linked	0.522
MYBPHL	TMEM98	ENSP00000349678	ENSP00000463245	Myosin-binding protein H-like; Fibronectin type III domain containing; Belongs to the immunoglobulin superfamily. MyBP family	Transmembrane protein 98	0.699
MYO1D	TMEM98	ENSP00000324527	ENSP00000463245	Unconventional myosin-Id; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments (By similarity); Myosins, class I	Transmembrane protein 98	0.522
TMEM176A	TMEM98	ENSP00000417626	ENSP00000463245	Transmembrane protein 176A; Membrane spanning 4-domains	Transmembrane protein 98	0.721
TMEM176A	TMEM9B	ENSP00000417626	ENSP00000433361	Transmembrane protein 176A; Membrane spanning 4-domains	Transmembrane protein 9B; Enhances production of proinflammatory cytokines induced by TNF, IL1B, and TLR ligands. Has a role in TNF activation of both the NF-kappaB and MAPK pathways; Belongs to the TMEM9 family	0.454
TMEM98	ATP1B3	ENSP00000463245	ENSP00000286371	Transmembrane protein 98	Sodium/potassium-transporting ATPase subunit beta-3; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-3 subunit is not known; ATPase Na+/K+ transporting subunits	0.787
TMEM98	CAPN7	ENSP00000463245	ENSP00000253693	Transmembrane protein 98	Calpain-7; Calcium-regulated non-lysosomal thiol-protease; Belongs to the peptidase C2 family	0.574

page 1 of 2

Network

Fusion

Experiments

Cooccurrence

Textmining

Coexpression

Databases

Neighborhood

© STRING Consortium 2020

Credits

Access

Info

About