TRIM16 protein (human) - STRING database

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TRIM16

Tripartite motif-containing protein 16; May play a role in the regulation of keratinocyte differentiation; Tripartite motif containing (564 aa)

Predicted Functional Partners:

TRAT1

0.673

LGALS3

0.643

BBOX1

0.641

FGF7

0.635

LAMTOR1

0.577

FGF10

0.574

TRIM16L

0.564

IL17RA

0.549

LMOD1

0.547

HNRNPUL2

0.541

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BBOX1	TRAT1	ENSP00000263182	ENSP00000295756	Gamma-butyrobetaine dioxygenase; Catalyzes the formation of L-carnitine from gamma- butyrobetaine; Belongs to the gamma-BBH/TMLD family	T-cell receptor-associated transmembrane adapter 1; Stabilizes the TCR (T-cell antigen receptor)/CD3 complex at the surface of T-cells	0.880
BBOX1	TRIM16	ENSP00000263182	ENSP00000463188	Gamma-butyrobetaine dioxygenase; Catalyzes the formation of L-carnitine from gamma- butyrobetaine; Belongs to the gamma-BBH/TMLD family	Tripartite motif-containing protein 16; May play a role in the regulation of keratinocyte differentiation; Tripartite motif containing	0.641
FGF10	FGF7	ENSP00000264664	ENSP00000267843	Fibroblast growth factor 10; Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. Required for normal branching morphogenesis. May play a role in wound healing; Belongs to the heparin-binding growth factors family	Fibroblast growth factor 7; Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. Required for normal branching morphogenesis. Growth factor active on keratinocytes. Possible major paracrine effector of normal epithelial cell proliferation; Belongs to the heparin-binding growth factors family	0.911
FGF10	TRIM16	ENSP00000264664	ENSP00000463188	Fibroblast growth factor 10; Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. Required for normal branching morphogenesis. May play a role in wound healing; Belongs to the heparin-binding growth factors family	Tripartite motif-containing protein 16; May play a role in the regulation of keratinocyte differentiation; Tripartite motif containing	0.574
FGF7	FGF10	ENSP00000267843	ENSP00000264664	Fibroblast growth factor 7; Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. Required for normal branching morphogenesis. Growth factor active on keratinocytes. Possible major paracrine effector of normal epithelial cell proliferation; Belongs to the heparin-binding growth factors family	Fibroblast growth factor 10; Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. Required for normal branching morphogenesis. May play a role in wound healing; Belongs to the heparin-binding growth factors family	0.911
FGF7	TRIM16	ENSP00000267843	ENSP00000463188	Fibroblast growth factor 7; Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. Required for normal branching morphogenesis. Growth factor active on keratinocytes. Possible major paracrine effector of normal epithelial cell proliferation; Belongs to the heparin-binding growth factors family	Tripartite motif-containing protein 16; May play a role in the regulation of keratinocyte differentiation; Tripartite motif containing	0.635
HNRNPUL2	TRIM16	ENSP00000301785	ENSP00000463188	Heterogeneous nuclear ribonucleoprotein U like 2	Tripartite motif-containing protein 16; May play a role in the regulation of keratinocyte differentiation; Tripartite motif containing	0.541
IL17RA	TRIM16	ENSP00000320936	ENSP00000463188	Interleukin-17 receptor A; Receptor for IL17A. Receptor for IL17F. Binds to IL17A with higher affinity than to IL17F. Binds IL17A and IL17F homodimers as part of a heterodimeric complex with IL17RC. Also binds heterodimers formed by IL17A and IL17F as part of a heterodimeric complex with IL17RC. Receptor for IL17C as part of a heterodimeric complex with IL17RE. Activation of IL17RA leads to induction of expression of inflammatory chemokines and cytokines such as CXCL1, CXCL8/IL8 and IL6; CD molecules	Tripartite motif-containing protein 16; May play a role in the regulation of keratinocyte differentiation; Tripartite motif containing	0.549
LAMTOR1	TRIM16	ENSP00000278671	ENSP00000463188	Ragulator complex protein LAMTOR1; As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. LAMTOR1 is directly responsible for anchoring the Ragulato [...]	Tripartite motif-containing protein 16; May play a role in the regulation of keratinocyte differentiation; Tripartite motif containing	0.577
LGALS3	TRAT1	ENSP00000254301	ENSP00000295756	Galectin-3; Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity). In the nucleus- acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells; Endogenous ligands	T-cell receptor-associated transmembrane adapter 1; Stabilizes the TCR (T-cell antigen receptor)/CD3 complex at the surface of T-cells	0.435
LGALS3	TRIM16	ENSP00000254301	ENSP00000463188	Galectin-3; Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity). In the nucleus- acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells; Endogenous ligands	Tripartite motif-containing protein 16; May play a role in the regulation of keratinocyte differentiation; Tripartite motif containing	0.643
LMOD1	TRIM16	ENSP00000356257	ENSP00000463188	Leiomodin-1; Mediates nucleation of actin filaments; Belongs to the tropomodulin family	Tripartite motif-containing protein 16; May play a role in the regulation of keratinocyte differentiation; Tripartite motif containing	0.547
TRAT1	BBOX1	ENSP00000295756	ENSP00000263182	T-cell receptor-associated transmembrane adapter 1; Stabilizes the TCR (T-cell antigen receptor)/CD3 complex at the surface of T-cells	Gamma-butyrobetaine dioxygenase; Catalyzes the formation of L-carnitine from gamma- butyrobetaine; Belongs to the gamma-BBH/TMLD family	0.880
TRAT1	LGALS3	ENSP00000295756	ENSP00000254301	T-cell receptor-associated transmembrane adapter 1; Stabilizes the TCR (T-cell antigen receptor)/CD3 complex at the surface of T-cells	Galectin-3; Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity). In the nucleus- acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells; Endogenous ligands	0.435
TRAT1	TRIM16	ENSP00000295756	ENSP00000463188	T-cell receptor-associated transmembrane adapter 1; Stabilizes the TCR (T-cell antigen receptor)/CD3 complex at the surface of T-cells	Tripartite motif-containing protein 16; May play a role in the regulation of keratinocyte differentiation; Tripartite motif containing	0.673
TRIM16	BBOX1	ENSP00000463188	ENSP00000263182	Tripartite motif-containing protein 16; May play a role in the regulation of keratinocyte differentiation; Tripartite motif containing	Gamma-butyrobetaine dioxygenase; Catalyzes the formation of L-carnitine from gamma- butyrobetaine; Belongs to the gamma-BBH/TMLD family	0.641
TRIM16	FGF10	ENSP00000463188	ENSP00000264664	Tripartite motif-containing protein 16; May play a role in the regulation of keratinocyte differentiation; Tripartite motif containing	Fibroblast growth factor 10; Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. Required for normal branching morphogenesis. May play a role in wound healing; Belongs to the heparin-binding growth factors family	0.574
TRIM16	FGF7	ENSP00000463188	ENSP00000267843	Tripartite motif-containing protein 16; May play a role in the regulation of keratinocyte differentiation; Tripartite motif containing	Fibroblast growth factor 7; Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. Required for normal branching morphogenesis. Growth factor active on keratinocytes. Possible major paracrine effector of normal epithelial cell proliferation; Belongs to the heparin-binding growth factors family	0.635
TRIM16	HNRNPUL2	ENSP00000463188	ENSP00000301785	Tripartite motif-containing protein 16; May play a role in the regulation of keratinocyte differentiation; Tripartite motif containing	Heterogeneous nuclear ribonucleoprotein U like 2	0.541
TRIM16	IL17RA	ENSP00000463188	ENSP00000320936	Tripartite motif-containing protein 16; May play a role in the regulation of keratinocyte differentiation; Tripartite motif containing	Interleukin-17 receptor A; Receptor for IL17A. Receptor for IL17F. Binds to IL17A with higher affinity than to IL17F. Binds IL17A and IL17F homodimers as part of a heterodimeric complex with IL17RC. Also binds heterodimers formed by IL17A and IL17F as part of a heterodimeric complex with IL17RC. Receptor for IL17C as part of a heterodimeric complex with IL17RE. Activation of IL17RA leads to induction of expression of inflammatory chemokines and cytokines such as CXCL1, CXCL8/IL8 and IL6; CD molecules	0.549

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