node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C17orf85 | C19orf47 | ENSP00000373657 | ENSP00000463159 | Nuclear cap-binding protein subunit 3; Associates with NCBP1/CBP80 to form an alternative cap- binding complex (CBC) which plays a key role in mRNA export. NCBP3 serves as adapter protein linking the capped RNAs (m7GpppG-capped RNA) to NCBP1/CBP80. Unlike the conventional CBC with NCBP2 which binds both small nuclear RNA (snRNA) and messenger (mRNA) and is involved in their export from the nucleus, the alternative CBC with NCBP3 does not bind snRNA and associates only with mRNA thereby playing a role in only mRNA export. The alternative CBC is particularly important in cellular stress [...] | Uncharacterized protein C19orf47; Chromosome 19 open reading frame 47 | 0.571 |
C17orf85 | THOC5 | ENSP00000373657 | ENSP00000420306 | Nuclear cap-binding protein subunit 3; Associates with NCBP1/CBP80 to form an alternative cap- binding complex (CBC) which plays a key role in mRNA export. NCBP3 serves as adapter protein linking the capped RNAs (m7GpppG-capped RNA) to NCBP1/CBP80. Unlike the conventional CBC with NCBP2 which binds both small nuclear RNA (snRNA) and messenger (mRNA) and is involved in their export from the nucleus, the alternative CBC with NCBP3 does not bind snRNA and associates only with mRNA thereby playing a role in only mRNA export. The alternative CBC is particularly important in cellular stress [...] | THO complex subunit 5 homolog; Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5’ end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. The TREX complex is essential [...] | 0.692 |
C19orf47 | C17orf85 | ENSP00000463159 | ENSP00000373657 | Uncharacterized protein C19orf47; Chromosome 19 open reading frame 47 | Nuclear cap-binding protein subunit 3; Associates with NCBP1/CBP80 to form an alternative cap- binding complex (CBC) which plays a key role in mRNA export. NCBP3 serves as adapter protein linking the capped RNAs (m7GpppG-capped RNA) to NCBP1/CBP80. Unlike the conventional CBC with NCBP2 which binds both small nuclear RNA (snRNA) and messenger (mRNA) and is involved in their export from the nucleus, the alternative CBC with NCBP3 does not bind snRNA and associates only with mRNA thereby playing a role in only mRNA export. The alternative CBC is particularly important in cellular stress [...] | 0.571 |
C19orf47 | C19orf54 | ENSP00000463159 | ENSP00000367564 | Uncharacterized protein C19orf47; Chromosome 19 open reading frame 47 | UPF0692 protein C19orf54; Chromosome 19 open reading frame 54; Belongs to the UPF0692 family | 0.559 |
C19orf47 | FAM124A | ENSP00000463159 | ENSP00000280057 | Uncharacterized protein C19orf47; Chromosome 19 open reading frame 47 | Protein FAM124A; Family with sequence similarity 124 member A; Belongs to the FAM124 family | 0.558 |
C19orf47 | GPATCH1 | ENSP00000463159 | ENSP00000170564 | Uncharacterized protein C19orf47; Chromosome 19 open reading frame 47 | G-patch domain containing 1; Belongs to the GPATCH1 family | 0.566 |
C19orf47 | THOC5 | ENSP00000463159 | ENSP00000420306 | Uncharacterized protein C19orf47; Chromosome 19 open reading frame 47 | THO complex subunit 5 homolog; Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5’ end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. The TREX complex is essential [...] | 0.546 |
C19orf47 | TIGD2 | ENSP00000463159 | ENSP00000317170 | Uncharacterized protein C19orf47; Chromosome 19 open reading frame 47 | Tigger transposable element-derived protein 2; Helix-turn-helix CENPB type domain containing; DNA transposon derived genes | 0.559 |
C19orf47 | TTC9B | ENSP00000463159 | ENSP00000311760 | Uncharacterized protein C19orf47; Chromosome 19 open reading frame 47 | Tetratricopeptide repeat domain containing | 0.535 |
C19orf47 | ZBTB45 | ENSP00000463159 | ENSP00000469089 | Uncharacterized protein C19orf47; Chromosome 19 open reading frame 47 | Zinc finger and BTB domain-containing protein 45; May be involved in transcriptional regulation (Probable). In the central nervous system, may play a role in glial cell differentiation (By similarity); BTB domain containing | 0.571 |
C19orf47 | ZNF546 | ENSP00000463159 | ENSP00000339823 | Uncharacterized protein C19orf47; Chromosome 19 open reading frame 47 | Zinc finger protein 546; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.540 |
C19orf47 | ZNF780A | ENSP00000463159 | ENSP00000400997 | Uncharacterized protein C19orf47; Chromosome 19 open reading frame 47 | Zinc finger protein 780A; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.583 |
C19orf54 | C19orf47 | ENSP00000367564 | ENSP00000463159 | UPF0692 protein C19orf54; Chromosome 19 open reading frame 54; Belongs to the UPF0692 family | Uncharacterized protein C19orf47; Chromosome 19 open reading frame 47 | 0.559 |
C19orf54 | TIGD2 | ENSP00000367564 | ENSP00000317170 | UPF0692 protein C19orf54; Chromosome 19 open reading frame 54; Belongs to the UPF0692 family | Tigger transposable element-derived protein 2; Helix-turn-helix CENPB type domain containing; DNA transposon derived genes | 0.550 |
C19orf54 | TTC9B | ENSP00000367564 | ENSP00000311760 | UPF0692 protein C19orf54; Chromosome 19 open reading frame 54; Belongs to the UPF0692 family | Tetratricopeptide repeat domain containing | 0.526 |
C19orf54 | ZNF546 | ENSP00000367564 | ENSP00000339823 | UPF0692 protein C19orf54; Chromosome 19 open reading frame 54; Belongs to the UPF0692 family | Zinc finger protein 546; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.530 |
C19orf54 | ZNF780A | ENSP00000367564 | ENSP00000400997 | UPF0692 protein C19orf54; Chromosome 19 open reading frame 54; Belongs to the UPF0692 family | Zinc finger protein 780A; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.570 |
FAM124A | C19orf47 | ENSP00000280057 | ENSP00000463159 | Protein FAM124A; Family with sequence similarity 124 member A; Belongs to the FAM124 family | Uncharacterized protein C19orf47; Chromosome 19 open reading frame 47 | 0.558 |
FAM124A | GPATCH1 | ENSP00000280057 | ENSP00000170564 | Protein FAM124A; Family with sequence similarity 124 member A; Belongs to the FAM124 family | G-patch domain containing 1; Belongs to the GPATCH1 family | 0.539 |
FAM124A | ZBTB45 | ENSP00000280057 | ENSP00000469089 | Protein FAM124A; Family with sequence similarity 124 member A; Belongs to the FAM124 family | Zinc finger and BTB domain-containing protein 45; May be involved in transcriptional regulation (Probable). In the central nervous system, may play a role in glial cell differentiation (By similarity); BTB domain containing | 0.558 |