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  • 11.0 [archived version]
STRINGSTRING
C17orf85 C17orf85 THOC5 THOC5 ZNF780A ZNF780A C19orf47 C19orf47 TTC9B TTC9B ZBTB45 ZBTB45 TIGD2 TIGD2 C19orf54 C19orf54 GPATCH1 GPATCH1 FAM124A FAM124A ZNF546 ZNF546
"C19orf47" - Uncharacterized protein C19orf47 in Homo sapiens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
C19orf47Uncharacterized protein C19orf47; Chromosome 19 open reading frame 47 (422 aa)    
Predicted Functional Partners:
ZNF780A
Zinc finger protein 780A; May be involved in transcriptional regulation; Zinc fingers C2H2-type (642 aa)
           
  0.583
ZBTB45
Zinc finger and BTB domain-containing protein 45; May be involved in transcriptional regulation (Probable). In the central nervous system, may play a role in glial cell differentiation (By similarity); BTB domain containing (511 aa)
           
  0.571
C17orf85
Nuclear cap-binding protein subunit 3; Associates with NCBP1/CBP80 to form an alternative cap- binding complex (CBC) which plays a key role in mRNA export. NCBP3 serves as adapter protein linking the capped RNAs (m7GpppG-capped RNA) to NCBP1/CBP80. Unlike the conventional CBC with NCBP2 which binds both small nuclear RNA (snRNA) and messenger (mRNA) and is involved in their export from the nucleus, the alternative CBC with NCBP3 does not bind snRNA and associates only with mRNA thereby playing a role in only mRNA export. The alternative CBC is particularly important in cellular stress [...] (620 aa)
       
      0.571
GPATCH1
G-patch domain containing 1; Belongs to the GPATCH1 family (931 aa)
     
   
  0.566
C19orf54
UPF0692 protein C19orf54; Chromosome 19 open reading frame 54; Belongs to the UPF0692 family (351 aa)
           
  0.559
TIGD2
Tigger transposable element-derived protein 2; Helix-turn-helix CENPB type domain containing; DNA transposon derived genes (525 aa)
           
  0.559
FAM124A
Protein FAM124A; Family with sequence similarity 124 member A; Belongs to the FAM124 family (582 aa)
           
  0.558
THOC5
THO complex subunit 5 homolog; Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5’ end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. The TREX complex is essential [...] (683 aa)
     
      0.546
ZNF546
Zinc finger protein 546; May be involved in transcriptional regulation; Zinc fingers C2H2-type (836 aa)
           
  0.540
TTC9B
Tetratricopeptide repeat domain containing (239 aa)
           
  0.535
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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