• Version:
  • 11.0 [archived version]
STRINGSTRING
NMT1 NMT1 PGK2 PGK2 ACOT2 ACOT2 MSH4 MSH4 SPATA33 SPATA33 DBNDD1 DBNDD1 SPATA2L SPATA2L ZNF276 ZNF276 DEF8 DEF8 CENPBD1 CENPBD1 SPIRE2 SPIRE2
"SPATA33" - Spermatogenesis-associated protein 33 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
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Textmining
[Homology]
Score
SPATA33Spermatogenesis-associated protein 33; Spermatogenesis associated 33 (140 aa)    
Predicted Functional Partners:
ACOT2
Acyl-coenzyme A thioesterase 2, mitochondrial; Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Displays high levels of activity on medium- and long chain acyl CoAs (483 aa)
       
      0.692
PGK2
Phosphoglycerate kinase 2; Essential for sperm motility and male fertility. Not required for the completion of spermatogenesis (By similarity); Belongs to the phosphoglycerate kinase family (417 aa)
     
   
  0.667
DEF8
Differentially expressed in FDCP 8 homolog; Positively regulates lysosome peripheral distribution and ruffled border formation in osteoclasts. Involved in bone resorption (512 aa)
           
  0.662
SPATA2L
Spermatogenesis-associated protein 2-like protein; Spermatogenesis associated 2 like (424 aa)
           
  0.657
CENPBD1
CENPB DNA-binding domain-containing protein 1; Helix-turn-helix CENPB type domain containing (187 aa)
           
  0.642
NMT1
Glycylpeptide N-tetradecanoyltransferase 1; Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins (496 aa)
           
  0.625
SPIRE2
Protein spire homolog 2; Acts as an actin nucleation factor, remains associated with the slow-growing pointed end of the new filament. Involved in intracellular vesicle transport along actin fibers, providing a novel link between actin cytoskeleton dynamics and intracellular transport. Required for asymmetric spindle positioning and asymmetric cell division during meiosis. Required for normal formation of the cleavage furrow and for polar body extrusion during female germ cell meiosis (714 aa)
     
   
  0.622
DBNDD1
Dysbindin domain containing 1 (278 aa)
     
   
  0.617
MSH4
MutS protein homolog 4; Involved in meiotic recombination. Required for reciprocal recombination and proper segregation of homologous chromosomes at meiosis; Belongs to the DNA mismatch repair MutS family (936 aa)
           
  0.606
ZNF276
Zinc finger protein 276; May be involved in transcriptional regulation; Zinc fingers C2H2-type (614 aa)
           
  0.604
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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