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  • 11.0 [archived version]
STRINGSTRING
CHURC1 CHURC1 BCORL1 BCORL1 TRIM28 TRIM28 OR1F1 OR1F1 ZNF75A ZNF75A TIGD7 TIGD7 KBTBD2 KBTBD2 CTTNBP2NL CTTNBP2NL C14orf180 C14orf180 FLRT2 FLRT2 NTNG1 NTNG1
"ZNF75A" - Zinc finger protein 75A in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ZNF75AZinc finger protein 75A; May be involved in transcriptional regulation; Zinc fingers C2H2-type (296 aa)    
Predicted Functional Partners:
TRIM28
Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at ’Lys-9’ (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 ’Lys-9 and ’Lys-14’ acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] (835 aa)
     
  0.904
TIGD7
Tigger transposable element-derived protein 7; Helix-turn-helix CENPB type domain containing; Belongs to the tigger transposable element derived protein family (549 aa)
       
 
  0.672
C14orf180
Nutritionally-regulated adipose and cardiac enriched protein homolog; Chromosome 14 open reading frame 180 (177 aa)
           
  0.644
OR1F1
Olfactory receptor 1F1; Odorant receptor; Olfactory receptors, family 1 (312 aa)
           
  0.520
KBTBD2
Kelch repeat and BTB domain containing 2 (623 aa)
       
 
  0.509
BCORL1
BCL-6 corepressor-like protein 1; Transcriptional corepressor. May specifically inhibit gene expression when recruited to promoter regions by sequence- specific DNA-binding proteins such as BCL6. This repression may be mediated at least in part by histone deacetylase activities which can associate with this corepressor; Belongs to the BCOR family (1711 aa)
       
 
  0.481
CTTNBP2NL
CTTNBP2 N-terminal-like protein; CTTNBP2 N-terminal like; STRIPAK complex (639 aa)
           
  0.471
NTNG1
Netrin-G1; Involved in controlling patterning and neuronal circuit formation at the laminar, cellular, subcellular and synaptic levels. Promotes neurite outgrowth of both axons and dendrites; Netrins (539 aa)
     
 
  0.461
FLRT2
Leucine-rich repeat transmembrane protein FLRT2; Functions in cell-cell adhesion, cell migration and axon guidance. Mediates cell-cell adhesion via its interactions with ADGRL3 and probably also other latrophilins that are expressed at the surface of adjacent cells. May play a role in the migration of cortical neurons during brain development via its interaction with UNC5D. Mediates axon growth cone collapse and plays a repulsive role in neuron guidance via its interaction with UNC5D, and possibly also other UNC-5 family members. Plays a role in fibroblast growth factor-mediated signal [...] (660 aa)
           
  0.454
CHURC1
Protein Churchill; Transcriptional activator that mediates FGF signaling during neural development. Plays a role in the regulation of cell movement (By similarity). Does not bind DNA by itself (140 aa)
           
  0.453
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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