• Version:
  • 11.0 [archived version]
STRINGSTRING
RAB39A RAB39A IGSF9B IGSF9B DAP3 DAP3 ZNF578 ZNF578 ENOX1 ENOX1 SH3BGR SH3BGR MIPOL1 MIPOL1 ZNF644 ZNF644
"ZNF578" - Zinc finger protein 578 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ZNF578Zinc finger protein 578; May be involved in transcriptional regulation; Zinc fingers C2H2-type (590 aa)    
Predicted Functional Partners:
IGSF9B
Protein turtle homolog B; Transmembrane protein which is abundantly expressed in interneurons, where it may regulate inhibitory synapse development. May mediate homophilic cell adhesion; Fibronectin type III domain containing (1437 aa)
           
  0.472
RAB39A
Ras-related protein Rab-39A; Plays a role in the maturation and acidification of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. Plays a role in vesicular trafficking. Plays a role in the fusion of phagosomes with lysosomes. Negatively regulates LPS-induced autophagosome formation in macrophages possibly by implicating PI3K. May be involved in multiple neurite formation (By similarity); Belongs to the small GTPase superfamily. Rab family (217 aa)
       
 
  0.464
MIPOL1
Mirror-image polydactyly 1 (442 aa)
           
  0.448
SH3BGR
SH3 domain-binding glutamic acid-rich protein; SH3 domain binding glutamate rich protein; Belongs to the SH3BGR family (239 aa)
       
 
  0.423
DAP3
28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death; Belongs to the mitochondrion-specific ribosomal protein mS29 family (398 aa)
           
  0.422
ENOX1
Ecto-NOX disulfide-thiol exchanger 1; Probably acts as a terminal oxidase of plasma electron transport from cytosolic NAD(P)H via hydroquinones to acceptors at the cell surface. Hydroquinone oxidase activity alternates with a protein disulfide-thiol interchange/oxidoreductase activity which may control physical membrane displacements associated with vesicle budding or cell enlargement. The activities oscillate with a period length of 24 minutes and play a role in control of the ultradian cellular biological clock; RNA binding motif containing (643 aa)
           
  0.422
ZNF644
Zinc finger protein 644; May be involved in transcriptional regulation (1327 aa)
           
  0.414
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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