• Version:
  • 11.0 [archived version]
STRINGSTRING
NPSR1 NPSR1 GPR83 GPR83 GPR12 GPR12 GPR162 GPR162 GPR146 GPR146 GPR153 GPR153 GPR139 GPR139 GPR148 GPR148 GPR110 GPR110 GPR111 GPR111 GPR141 GPR141
"GPR139" - Probable G-protein coupled receptor 139 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GPR139Probable G-protein coupled receptor 139; Orphan receptor. Seems to act through a G(q/11)-mediated pathway; G protein-coupled receptors, Class A orphans (353 aa)    
Predicted Functional Partners:
GPR146
Probable G-protein coupled receptor 146; Orphan receptor; G protein-coupled receptors, Class A orphans (333 aa)
           
  0.788
GPR141
Probable G-protein coupled receptor 141; Orphan receptor; G protein-coupled receptors, Class A orphans (305 aa)
           
  0.759
GPR148
Probable G-protein coupled receptor 148; Orphan receptor; G protein-coupled receptors, Class A orphans (347 aa)
           
  0.737
GPR111
Adhesion G-protein coupled receptor F2; Orphan receptor (708 aa)
           
  0.726
GPR110
Adhesion G-protein coupled receptor F1; Orphan receptor; Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily (910 aa)
           
  0.716
NPSR1
Neuropeptide S receptor; G-protein coupled receptor for neuropeptide S (NPS). Promotes mobilization of intracellular Ca(2+) stores. Inhibits cell growth in response to NPS binding. Involved in pathogenesis of asthma and other IgE-mediated diseases (390 aa)
     
   
  0.713
GPR83
Probable G-protein coupled receptor 83; Orphan receptor. Could be a neuropeptide Y receptor; G protein-coupled receptors, Class A orphans (423 aa)
     
   
  0.710
GPR162
Probable G-protein coupled receptor 162; Orphan receptor; G protein-coupled receptors, Class A orphans (588 aa)
           
  0.665
GPR153
Probable G-protein coupled receptor 153; Orphan receptor; G protein-coupled receptors, Class A orphans (609 aa)
     
   
  0.635
GPR12
G-protein coupled receptor 12; Promotes neurite outgrowth and blocks myelin inhibition in neurons (By similarity). Receptor with constitutive G(s) signaling activity that stimulates cyclic AMP production; G protein-coupled receptors, Class A orphans (334 aa)
     
   
  0.625
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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