node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ARAP3 | MITD1 | ENSP00000239440 | ENSP00000289359 | Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3; Phosphatidylinositol 3,4,5-trisphosphate-dependent GTPase-activating protein that modulates actin cytoskeleton remodeling by regulating ARF and RHO family members. Is activated by phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3) binding. Can be activated by phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4,5)P2) binding, albeit with lower efficiency. Acts on ARF6, RAC1, RHOA and CDC42. Plays a role in the internalization of anthrax toxin; Ankyrin repeat domain containing | MIT domain-containing protein 1; Required for efficient abscission at the end of cytokinesis, together with components of the ESCRT-III complex | 0.404 |
ARAP3 | SMAGP | ENSP00000239440 | ENSP00000475068 | Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3; Phosphatidylinositol 3,4,5-trisphosphate-dependent GTPase-activating protein that modulates actin cytoskeleton remodeling by regulating ARF and RHO family members. Is activated by phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3) binding. Can be activated by phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4,5)P2) binding, albeit with lower efficiency. Acts on ARF6, RAC1, RHOA and CDC42. Plays a role in the internalization of anthrax toxin; Ankyrin repeat domain containing | Small cell adhesion glycoprotein; May play a role in epithelial cell-cell contacts. May play a role in tumor invasiveness and metastasis formation | 0.449 |
ARAP3 | TSNAXIP1 | ENSP00000239440 | ENSP00000457241 | Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3; Phosphatidylinositol 3,4,5-trisphosphate-dependent GTPase-activating protein that modulates actin cytoskeleton remodeling by regulating ARF and RHO family members. Is activated by phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3) binding. Can be activated by phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4,5)P2) binding, albeit with lower efficiency. Acts on ARF6, RAC1, RHOA and CDC42. Plays a role in the internalization of anthrax toxin; Ankyrin repeat domain containing | Translin-associated factor X-interacting protein 1; Possible role in spermatogenesis | 0.460 |
C8orf33 | KIAA1522 | ENSP00000330361 | ENSP00000383851 | UPF0488 protein C8orf33; Chromosome 8 open reading frame 33; Belongs to the UPF0488 family | Uncharacterized protein KIAA1522; KIAA1522 | 0.538 |
C8orf33 | TSNAXIP1 | ENSP00000330361 | ENSP00000457241 | UPF0488 protein C8orf33; Chromosome 8 open reading frame 33; Belongs to the UPF0488 family | Translin-associated factor X-interacting protein 1; Possible role in spermatogenesis | 0.585 |
COL26A1 | MITD1 | ENSP00000318234 | ENSP00000289359 | Collagen type XXVI alpha 1 chain; Collagens | MIT domain-containing protein 1; Required for efficient abscission at the end of cytokinesis, together with components of the ESCRT-III complex | 0.471 |
COL26A1 | SMAGP | ENSP00000318234 | ENSP00000475068 | Collagen type XXVI alpha 1 chain; Collagens | Small cell adhesion glycoprotein; May play a role in epithelial cell-cell contacts. May play a role in tumor invasiveness and metastasis formation | 0.483 |
COL26A1 | TSNAXIP1 | ENSP00000318234 | ENSP00000457241 | Collagen type XXVI alpha 1 chain; Collagens | Translin-associated factor X-interacting protein 1; Possible role in spermatogenesis | 0.501 |
GFOD2 | TSNAXIP1 | ENSP00000268797 | ENSP00000457241 | Glucose-fructose oxidoreductase domain-containing protein 2; Promotes matrix assembly | Translin-associated factor X-interacting protein 1; Possible role in spermatogenesis | 0.543 |
KCNH5 | SMAGP | ENSP00000321427 | ENSP00000475068 | Potassium voltage-gated channel subfamily H member 5; Pore-forming (alpha) subunit of voltage-gated potassium channel. Elicits a non-inactivating outward rectifying current. Channel properties may be modulated by cAMP and subunit assembly; Belongs to the potassium channel family. H (Eag) (TC 1.A.1.20) subfamily. Kv10.2/KCNH5 sub-subfamily | Small cell adhesion glycoprotein; May play a role in epithelial cell-cell contacts. May play a role in tumor invasiveness and metastasis formation | 0.440 |
KCNH5 | TSNAXIP1 | ENSP00000321427 | ENSP00000457241 | Potassium voltage-gated channel subfamily H member 5; Pore-forming (alpha) subunit of voltage-gated potassium channel. Elicits a non-inactivating outward rectifying current. Channel properties may be modulated by cAMP and subunit assembly; Belongs to the potassium channel family. H (Eag) (TC 1.A.1.20) subfamily. Kv10.2/KCNH5 sub-subfamily | Translin-associated factor X-interacting protein 1; Possible role in spermatogenesis | 0.463 |
KIAA1522 | C8orf33 | ENSP00000383851 | ENSP00000330361 | Uncharacterized protein KIAA1522; KIAA1522 | UPF0488 protein C8orf33; Chromosome 8 open reading frame 33; Belongs to the UPF0488 family | 0.538 |
KIAA1522 | TSNAXIP1 | ENSP00000383851 | ENSP00000457241 | Uncharacterized protein KIAA1522; KIAA1522 | Translin-associated factor X-interacting protein 1; Possible role in spermatogenesis | 0.528 |
MITD1 | ARAP3 | ENSP00000289359 | ENSP00000239440 | MIT domain-containing protein 1; Required for efficient abscission at the end of cytokinesis, together with components of the ESCRT-III complex | Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3; Phosphatidylinositol 3,4,5-trisphosphate-dependent GTPase-activating protein that modulates actin cytoskeleton remodeling by regulating ARF and RHO family members. Is activated by phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3) binding. Can be activated by phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4,5)P2) binding, albeit with lower efficiency. Acts on ARF6, RAC1, RHOA and CDC42. Plays a role in the internalization of anthrax toxin; Ankyrin repeat domain containing | 0.404 |
MITD1 | COL26A1 | ENSP00000289359 | ENSP00000318234 | MIT domain-containing protein 1; Required for efficient abscission at the end of cytokinesis, together with components of the ESCRT-III complex | Collagen type XXVI alpha 1 chain; Collagens | 0.471 |
MITD1 | SMAGP | ENSP00000289359 | ENSP00000475068 | MIT domain-containing protein 1; Required for efficient abscission at the end of cytokinesis, together with components of the ESCRT-III complex | Small cell adhesion glycoprotein; May play a role in epithelial cell-cell contacts. May play a role in tumor invasiveness and metastasis formation | 0.565 |
MITD1 | SPATA4 | ENSP00000289359 | ENSP00000280191 | MIT domain-containing protein 1; Required for efficient abscission at the end of cytokinesis, together with components of the ESCRT-III complex | Spermatogenesis-associated protein 4; Spermatogenesis associated 4 | 0.459 |
MITD1 | TSNAXIP1 | ENSP00000289359 | ENSP00000457241 | MIT domain-containing protein 1; Required for efficient abscission at the end of cytokinesis, together with components of the ESCRT-III complex | Translin-associated factor X-interacting protein 1; Possible role in spermatogenesis | 0.569 |
SMAGP | ARAP3 | ENSP00000475068 | ENSP00000239440 | Small cell adhesion glycoprotein; May play a role in epithelial cell-cell contacts. May play a role in tumor invasiveness and metastasis formation | Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3; Phosphatidylinositol 3,4,5-trisphosphate-dependent GTPase-activating protein that modulates actin cytoskeleton remodeling by regulating ARF and RHO family members. Is activated by phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3) binding. Can be activated by phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4,5)P2) binding, albeit with lower efficiency. Acts on ARF6, RAC1, RHOA and CDC42. Plays a role in the internalization of anthrax toxin; Ankyrin repeat domain containing | 0.449 |
SMAGP | COL26A1 | ENSP00000475068 | ENSP00000318234 | Small cell adhesion glycoprotein; May play a role in epithelial cell-cell contacts. May play a role in tumor invasiveness and metastasis formation | Collagen type XXVI alpha 1 chain; Collagens | 0.483 |