node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABHD13 | ZDHHC7 | ENSP00000365063 | ENSP00000456782 | Protein ABHD13; Abhydrolase domain containing 13 | Palmitoyltransferase; Zinc finger DHHC-type containing 7; Belongs to the DHHC palmitoyltransferase family | 0.601 |
COTL1 | JPH3 | ENSP00000262428 | ENSP00000284262 | Coactosin-like protein; Binds to F-actin in a calcium-independent manner. Has no direct effect on actin depolymerization. Acts as a chaperone for ALOX5 (5LO), influencing both its stability and activity in leukotrienes synthesis | Junctophilin-3; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. JPH3 is brain- specific and appears to have an active role in certain neurons involved in motor coordination and memory | 0.500 |
COTL1 | ZDHHC7 | ENSP00000262428 | ENSP00000456782 | Coactosin-like protein; Binds to F-actin in a calcium-independent manner. Has no direct effect on actin depolymerization. Acts as a chaperone for ALOX5 (5LO), influencing both its stability and activity in leukotrienes synthesis | Palmitoyltransferase; Zinc finger DHHC-type containing 7; Belongs to the DHHC palmitoyltransferase family | 0.504 |
CYB5B | SDR42E1 | ENSP00000308430 | ENSP00000332407 | Cytochrome b5 type B; Cytochrome b5 is a membrane bound hemoprotein which function as an electron carrier for several membrane bound oxygenases | Short chain dehydrogenase/reductase family 42E, member 1 | 0.731 |
CYB5B | ZDHHC7 | ENSP00000308430 | ENSP00000456782 | Cytochrome b5 type B; Cytochrome b5 is a membrane bound hemoprotein which function as an electron carrier for several membrane bound oxygenases | Palmitoyltransferase; Zinc finger DHHC-type containing 7; Belongs to the DHHC palmitoyltransferase family | 0.665 |
GOLGA7 | ZDHHC7 | ENSP00000350378 | ENSP00000456782 | Golgin subfamily A member 7; May be involved in protein transport from Golgi to cell surface. The ZDHHC9-GOLGA7 complex is a palmitoyltransferase specific for HRAS and NRAS | Palmitoyltransferase; Zinc finger DHHC-type containing 7; Belongs to the DHHC palmitoyltransferase family | 0.573 |
JPH3 | COTL1 | ENSP00000284262 | ENSP00000262428 | Junctophilin-3; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. JPH3 is brain- specific and appears to have an active role in certain neurons involved in motor coordination and memory | Coactosin-like protein; Binds to F-actin in a calcium-independent manner. Has no direct effect on actin depolymerization. Acts as a chaperone for ALOX5 (5LO), influencing both its stability and activity in leukotrienes synthesis | 0.500 |
JPH3 | ZDHHC7 | ENSP00000284262 | ENSP00000456782 | Junctophilin-3; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. JPH3 is brain- specific and appears to have an active role in certain neurons involved in motor coordination and memory | Palmitoyltransferase; Zinc finger DHHC-type containing 7; Belongs to the DHHC palmitoyltransferase family | 0.495 |
KHNYN | ZDHHC7 | ENSP00000251343 | ENSP00000456782 | Protein KHNYN; KH and NYN domain containing; Belongs to the N4BP1 family | Palmitoyltransferase; Zinc finger DHHC-type containing 7; Belongs to the DHHC palmitoyltransferase family | 0.480 |
PBX2 | ZDHHC7 | ENSP00000364190 | ENSP00000456782 | Pre-B-cell leukemia transcription factor 2; Transcriptional activator that binds the sequence 5’- ATCAATCAA-3’. Activates transcription of PF4 in complex with MEIS1; TALE class homeoboxes and pseudogenes | Palmitoyltransferase; Zinc finger DHHC-type containing 7; Belongs to the DHHC palmitoyltransferase family | 0.565 |
PPT1 | ZDHHC7 | ENSP00000394863 | ENSP00000456782 | Palmitoyl-protein thioesterase 1; Removes thioester-linked fatty acyl groups such as palmitate from modified cysteine residues in proteins or peptides during lysosomal degradation. Prefers acyl chain lengths of 14 to 18 carbons; Belongs to the palmitoyl-protein thioesterase family | Palmitoyltransferase; Zinc finger DHHC-type containing 7; Belongs to the DHHC palmitoyltransferase family | 0.539 |
SDR42E1 | CYB5B | ENSP00000332407 | ENSP00000308430 | Short chain dehydrogenase/reductase family 42E, member 1 | Cytochrome b5 type B; Cytochrome b5 is a membrane bound hemoprotein which function as an electron carrier for several membrane bound oxygenases | 0.731 |
SDR42E1 | ZDHHC7 | ENSP00000332407 | ENSP00000456782 | Short chain dehydrogenase/reductase family 42E, member 1 | Palmitoyltransferase; Zinc finger DHHC-type containing 7; Belongs to the DHHC palmitoyltransferase family | 0.594 |
ZDHHC7 | ABHD13 | ENSP00000456782 | ENSP00000365063 | Palmitoyltransferase; Zinc finger DHHC-type containing 7; Belongs to the DHHC palmitoyltransferase family | Protein ABHD13; Abhydrolase domain containing 13 | 0.601 |
ZDHHC7 | COTL1 | ENSP00000456782 | ENSP00000262428 | Palmitoyltransferase; Zinc finger DHHC-type containing 7; Belongs to the DHHC palmitoyltransferase family | Coactosin-like protein; Binds to F-actin in a calcium-independent manner. Has no direct effect on actin depolymerization. Acts as a chaperone for ALOX5 (5LO), influencing both its stability and activity in leukotrienes synthesis | 0.504 |
ZDHHC7 | CYB5B | ENSP00000456782 | ENSP00000308430 | Palmitoyltransferase; Zinc finger DHHC-type containing 7; Belongs to the DHHC palmitoyltransferase family | Cytochrome b5 type B; Cytochrome b5 is a membrane bound hemoprotein which function as an electron carrier for several membrane bound oxygenases | 0.665 |
ZDHHC7 | GOLGA7 | ENSP00000456782 | ENSP00000350378 | Palmitoyltransferase; Zinc finger DHHC-type containing 7; Belongs to the DHHC palmitoyltransferase family | Golgin subfamily A member 7; May be involved in protein transport from Golgi to cell surface. The ZDHHC9-GOLGA7 complex is a palmitoyltransferase specific for HRAS and NRAS | 0.573 |
ZDHHC7 | JPH3 | ENSP00000456782 | ENSP00000284262 | Palmitoyltransferase; Zinc finger DHHC-type containing 7; Belongs to the DHHC palmitoyltransferase family | Junctophilin-3; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. JPH3 is brain- specific and appears to have an active role in certain neurons involved in motor coordination and memory | 0.495 |
ZDHHC7 | KHNYN | ENSP00000456782 | ENSP00000251343 | Palmitoyltransferase; Zinc finger DHHC-type containing 7; Belongs to the DHHC palmitoyltransferase family | Protein KHNYN; KH and NYN domain containing; Belongs to the N4BP1 family | 0.480 |
ZDHHC7 | PBX2 | ENSP00000456782 | ENSP00000364190 | Palmitoyltransferase; Zinc finger DHHC-type containing 7; Belongs to the DHHC palmitoyltransferase family | Pre-B-cell leukemia transcription factor 2; Transcriptional activator that binds the sequence 5’- ATCAATCAA-3’. Activates transcription of PF4 in complex with MEIS1; TALE class homeoboxes and pseudogenes | 0.565 |