GOLGA8J protein (human) - STRING database

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

GOLGA8J

Golgin A8 family member J; Belongs to the GOLGA8 family (632 aa)

Predicted Functional Partners:

ZNF626

0.588

ENSG00000278599

0.479

TMED3

0.473

ZKSCAN1

0.463

B4GALT2

0.454

FXYD4

0.448

AGGF1

0.447

TAF1C

0.443

JTB

0.443

EAPP

0.442

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but resolution at 400 dpi

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as simple tabular text output:

download

TSV: tab separated values - can be opened in Excel

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGGF1	GOLGA8J	ENSP00000316109	ENSP00000456401	Angiogenic factor with G patch and FHA domains 1; Promotes angiogenesis and the proliferation of endothelial cells. Able to bind to endothelial cells and promote cell proliferation, suggesting that it may act in an autocrine fashion; G-patch domain containing	Golgin A8 family member J; Belongs to the GOLGA8 family	0.447
B4GALT2	GOLGA8J	ENSP00000310696	ENSP00000456401	Beta-1,4-galactosyltransferase 2; Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids. Can produce lactose; Beta 4-glycosyltransferases	Golgin A8 family member J; Belongs to the GOLGA8 family	0.454
EAPP	GOLGA8J	ENSP00000250454	ENSP00000456401	E2F-associated phosphoprotein; May play an important role in the fine-tuning of both major E2F1 activities, the regulation of the cell-cycle and the induction of apoptosis. Promotes S-phase entry, and inhibits p14(ARP) expression	Golgin A8 family member J; Belongs to the GOLGA8 family	0.442
ENSG00000278599	GOLGA8J	ENSP00000483965	ENSP00000456401	TBC1 domain family member 3E; Acts as a GTPase activating protein for RAB5. Does not act on RAB4 or RAB11 (By similarity)	Golgin A8 family member J; Belongs to the GOLGA8 family	0.479
FXYD4	GOLGA8J	ENSP00000483791	ENSP00000456401	FXYD domain containing ion transport regulator 4	Golgin A8 family member J; Belongs to the GOLGA8 family	0.448
GOLGA8J	AGGF1	ENSP00000456401	ENSP00000316109	Golgin A8 family member J; Belongs to the GOLGA8 family	Angiogenic factor with G patch and FHA domains 1; Promotes angiogenesis and the proliferation of endothelial cells. Able to bind to endothelial cells and promote cell proliferation, suggesting that it may act in an autocrine fashion; G-patch domain containing	0.447
GOLGA8J	B4GALT2	ENSP00000456401	ENSP00000310696	Golgin A8 family member J; Belongs to the GOLGA8 family	Beta-1,4-galactosyltransferase 2; Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids. Can produce lactose; Beta 4-glycosyltransferases	0.454
GOLGA8J	EAPP	ENSP00000456401	ENSP00000250454	Golgin A8 family member J; Belongs to the GOLGA8 family	E2F-associated phosphoprotein; May play an important role in the fine-tuning of both major E2F1 activities, the regulation of the cell-cycle and the induction of apoptosis. Promotes S-phase entry, and inhibits p14(ARP) expression	0.442
GOLGA8J	ENSG00000278599	ENSP00000456401	ENSP00000483965	Golgin A8 family member J; Belongs to the GOLGA8 family	TBC1 domain family member 3E; Acts as a GTPase activating protein for RAB5. Does not act on RAB4 or RAB11 (By similarity)	0.479
GOLGA8J	FXYD4	ENSP00000456401	ENSP00000483791	Golgin A8 family member J; Belongs to the GOLGA8 family	FXYD domain containing ion transport regulator 4	0.448
GOLGA8J	JTB	ENSP00000456401	ENSP00000271843	Golgin A8 family member J; Belongs to the GOLGA8 family	Protein JTB; Required for normal cytokinesis during mitosis. Plays a role in the regulation of cell proliferation. May be a component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Increases AURKB activity. Inhibits apoptosis induced by TGFB1 (By similarity). Overexpression induces swelling of mitochondria and reduces mitochondrial membrane [...]	0.443
GOLGA8J	TAF1C	ENSP00000456401	ENSP00000455265	Golgin A8 family member J; Belongs to the GOLGA8 family	TATA box-binding protein-associated factor RNA polymerase I subunit C; Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits. Recruits RNA polymerase I to the rRNA gene promoter via [...]	0.443
GOLGA8J	TMED3	ENSP00000456401	ENSP00000299705	Golgin A8 family member J; Belongs to the GOLGA8 family	Transmembrane emp24 domain-containing protein 3; Potential role in vesicular protein trafficking, mainly in the early secretory pathway. Contributes to the coupled localization of TMED2 and TMED10 in the cis-Golgi network; Belongs to the EMP24/GP25L family	0.473
GOLGA8J	ZKSCAN1	ENSP00000456401	ENSP00000323148	Golgin A8 family member J; Belongs to the GOLGA8 family	Zinc finger protein with KRAB and SCAN domains 1; May be involved in transcriptional regulation; SCAN domain containing	0.463
GOLGA8J	ZNF626	ENSP00000456401	ENSP00000469958	Golgin A8 family member J; Belongs to the GOLGA8 family	Zinc finger protein 626; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.588
JTB	GOLGA8J	ENSP00000271843	ENSP00000456401	Protein JTB; Required for normal cytokinesis during mitosis. Plays a role in the regulation of cell proliferation. May be a component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Increases AURKB activity. Inhibits apoptosis induced by TGFB1 (By similarity). Overexpression induces swelling of mitochondria and reduces mitochondrial membrane [...]	Golgin A8 family member J; Belongs to the GOLGA8 family	0.443
TAF1C	GOLGA8J	ENSP00000455265	ENSP00000456401	TATA box-binding protein-associated factor RNA polymerase I subunit C; Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits. Recruits RNA polymerase I to the rRNA gene promoter via [...]	Golgin A8 family member J; Belongs to the GOLGA8 family	0.443
TMED3	GOLGA8J	ENSP00000299705	ENSP00000456401	Transmembrane emp24 domain-containing protein 3; Potential role in vesicular protein trafficking, mainly in the early secretory pathway. Contributes to the coupled localization of TMED2 and TMED10 in the cis-Golgi network; Belongs to the EMP24/GP25L family	Golgin A8 family member J; Belongs to the GOLGA8 family	0.473
ZKSCAN1	GOLGA8J	ENSP00000323148	ENSP00000456401	Zinc finger protein with KRAB and SCAN domains 1; May be involved in transcriptional regulation; SCAN domain containing	Golgin A8 family member J; Belongs to the GOLGA8 family	0.463
ZNF626	GOLGA8J	ENSP00000469958	ENSP00000456401	Zinc finger protein 626; May be involved in transcriptional regulation; Zinc fingers C2H2-type	Golgin A8 family member J; Belongs to the GOLGA8 family	0.588

Network

Cooccurrence

Experiments

Coexpression

Textmining

Neighborhood

Databases

Fusion

© STRING Consortium 2020

Credits

Access

Info

About