• Version:
  • 11.0 [archived version]
STRINGSTRING
MEIS2 MEIS2 ZNF503 ZNF503 TMCO5A TMCO5A C1orf146 C1orf146 DPH6 DPH6 C15orf41 C15orf41 CDCA7 CDCA7 CSNK1A1 CSNK1A1 KIF23 KIF23 SEC23B SEC23B CDAN1 CDAN1
"C15orf41" - Uncharacterized protein C15orf41 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
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C15orf41Uncharacterized protein C15orf41; Chromosome 15 open reading frame 41 (281 aa)    
Predicted Functional Partners:
C1orf146
Uncharacterized protein C1orf146; Chromosome 1 open reading frame 146 (180 aa)
           
  0.767
CDAN1
Codanin-1; May act as a negative regulator of ASF1 in chromatin assembly (1227 aa)
           
  0.706
DPH6
Diphthine--ammonia ligase; Amidase that catalyzes the last step of diphthamide biosynthesis using ammonium and ATP. Diphthamide biosynthesis consists in the conversion of an L-histidine residue in the translation elongation factor (EEF2) to diphthamide (By similarity) (267 aa)
           
  0.699
SEC23B
Protein transport protein Sec23B; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex (767 aa)
           
  0.669
CSNK1A1
Casein kinase I isoform alpha; Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at ’Ser-45’. May phosphorylate PER1 and PER2. May play a role in segregating chromosomes during mitosis. May play a role in keratin cytoskeleton disassembly and thereby, it may regulate epithelial cell migration (365 aa)
           
  0.637
MEIS2
Homeobox protein Meis2; Involved in transcriptional regulation. Binds to HOX or PBX proteins to form dimers, or to a DNA-bound dimer of PBX and HOX proteins and thought to have a role in stabilization of the homeoprotein-DNA complex. Isoform 3 is required for the activity of a PDX1-PBX1b-MEIS2b complex in pancreatic acinar cells involved in the transcriptional activation of the ELA1 enhancer; the complex binds to the enhancer B element and cooperates with the transcription factor 1 complex (PTF1) bound to the enhancer A element; MEIS2 is not involved in complex DNA-binding. Probably in [...] (477 aa)
           
  0.608
TMCO5A
Transmembrane and coiled-coil domains 5A; Belongs to the TMCO5 family (288 aa)
           
  0.571
CDCA7
Cell division cycle-associated protein 7; Participates in MYC-mediated cell transformation and apoptosis; induces anchorage-independent growth and clonogenicity in lymphoblastoid cells. Insufficient to induce tumorigenicity when overexpressed but contributes to MYC-mediated tumorigenesis. May play a role as transcriptional regulator (450 aa)
           
  0.558
KIF23
Kinesin-like protein KIF23; Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis. Essential for cytokinesis in Rho-mediated signaling. Required for the localization of ECT2 to the central spindle. Plus-end-directed motor enzyme that moves antiparallel microtubules in vitro; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family (960 aa)
           
  0.544
ZNF503
Zinc finger protein 503; May function as a transcriptional repressor; Zinc fingers C2H2-type (646 aa)
           
  0.523
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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