ENSG00000260537 protein (human)

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Score

ENSG00000260537

ATP-dependent RNA helicase DDX19B (261 aa)

Predicted Functional Partners:

GLE1

0.840

NUP214

0.732

NXF1

0.709

UBALD1

0.585

OR2T5

0.573

ERCC6L2

0.540

NXF5

0.537

TMEM194A

0.522

DDX51

0.512

RBM15B

0.512

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DDX51	ENSG00000260537	ENSP00000380495	ENSP00000454699	ATP-dependent RNA helicase DDX51; ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits; Belongs to the DEAD box helicase family. DDX51/DBP6 subfamily	ATP-dependent RNA helicase DDX19B	0.512
ENSG00000260537	DDX51	ENSP00000454699	ENSP00000380495	ATP-dependent RNA helicase DDX19B	ATP-dependent RNA helicase DDX51; ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits; Belongs to the DEAD box helicase family. DDX51/DBP6 subfamily	0.512
ENSG00000260537	ERCC6L2	ENSP00000454699	ENSP00000288985	ATP-dependent RNA helicase DDX19B	DNA excision repair protein ERCC-6-like 2; May be involved in early DNA damage response	0.540
ENSG00000260537	GLE1	ENSP00000454699	ENSP00000308622	ATP-dependent RNA helicase DDX19B	Nucleoporin GLE1; Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. May be involved in the terminal step of the mRNA transport through the nuclear pore complex (NPC); Belongs to the GLE1 family	0.840
ENSG00000260537	NUP214	ENSP00000454699	ENSP00000352400	ATP-dependent RNA helicase DDX19B	Nuclear pore complex protein Nup214; May serve as a docking site in the receptor-mediated import of substrates across the nuclear pore complex; Nucleoporins	0.732
ENSG00000260537	NXF1	ENSP00000454699	ENSP00000436679	ATP-dependent RNA helicase DDX19B	Nuclear RNA export factor 1; Involved in the nuclear export of mRNA species bearing retroviral constitutive transport elements (CTE) and in the export of mRNA from the nucleus to the cytoplasm (TAP/NFX1 pathway). The NXF1-NXT1 heterodimer is involved in the export of HSP70 mRNA in conjunction with ALYREF/THOC4 and THOC5 components of the TREX complex. ALYREF/THOC4-bound mRNA is thought to be transferred to the NXF1-NXT1 heterodimer for export	0.709
ENSG00000260537	NXF5	ENSP00000454699	ENSP00000426978	ATP-dependent RNA helicase DDX19B	Nuclear RNA export factor 5; Could be involved in the export of mRNA from the nucleus to the cytoplasm. Could also have a role in polarized cytoplasmic transport and localization of mRNA in neurons	0.537
ENSG00000260537	OR2T5	ENSP00000454699	ENSP00000355429	ATP-dependent RNA helicase DDX19B	Olfactory receptor 2T5; Odorant receptor; Olfactory receptors, family 2	0.573
ENSG00000260537	RBM15B	ENSP00000454699	ENSP00000454545	ATP-dependent RNA helicase DDX19B	Putative RNA-binding protein 15B; May function in the regulation of alternative or illicit splicing; Belongs to the RRM Spen family	0.512
ENSG00000260537	TMEM194A	ENSP00000454699	ENSP00000300128	ATP-dependent RNA helicase DDX19B	Transmembrane protein 194A	0.522
ENSG00000260537	UBALD1	ENSP00000454699	ENSP00000283474	ATP-dependent RNA helicase DDX19B	UBA-like domain-containing protein 1; UBA like domain containing 1	0.585
ERCC6L2	ENSG00000260537	ENSP00000288985	ENSP00000454699	DNA excision repair protein ERCC-6-like 2; May be involved in early DNA damage response	ATP-dependent RNA helicase DDX19B	0.540
GLE1	ENSG00000260537	ENSP00000308622	ENSP00000454699	Nucleoporin GLE1; Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. May be involved in the terminal step of the mRNA transport through the nuclear pore complex (NPC); Belongs to the GLE1 family	ATP-dependent RNA helicase DDX19B	0.840
GLE1	NUP214	ENSP00000308622	ENSP00000352400	Nucleoporin GLE1; Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. May be involved in the terminal step of the mRNA transport through the nuclear pore complex (NPC); Belongs to the GLE1 family	Nuclear pore complex protein Nup214; May serve as a docking site in the receptor-mediated import of substrates across the nuclear pore complex; Nucleoporins	0.996
GLE1	NXF1	ENSP00000308622	ENSP00000436679	Nucleoporin GLE1; Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. May be involved in the terminal step of the mRNA transport through the nuclear pore complex (NPC); Belongs to the GLE1 family	Nuclear RNA export factor 1; Involved in the nuclear export of mRNA species bearing retroviral constitutive transport elements (CTE) and in the export of mRNA from the nucleus to the cytoplasm (TAP/NFX1 pathway). The NXF1-NXT1 heterodimer is involved in the export of HSP70 mRNA in conjunction with ALYREF/THOC4 and THOC5 components of the TREX complex. ALYREF/THOC4-bound mRNA is thought to be transferred to the NXF1-NXT1 heterodimer for export	0.989
GLE1	NXF5	ENSP00000308622	ENSP00000426978	Nucleoporin GLE1; Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. May be involved in the terminal step of the mRNA transport through the nuclear pore complex (NPC); Belongs to the GLE1 family	Nuclear RNA export factor 5; Could be involved in the export of mRNA from the nucleus to the cytoplasm. Could also have a role in polarized cytoplasmic transport and localization of mRNA in neurons	0.537
NUP214	ENSG00000260537	ENSP00000352400	ENSP00000454699	Nuclear pore complex protein Nup214; May serve as a docking site in the receptor-mediated import of substrates across the nuclear pore complex; Nucleoporins	ATP-dependent RNA helicase DDX19B	0.732
NUP214	GLE1	ENSP00000352400	ENSP00000308622	Nuclear pore complex protein Nup214; May serve as a docking site in the receptor-mediated import of substrates across the nuclear pore complex; Nucleoporins	Nucleoporin GLE1; Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. May be involved in the terminal step of the mRNA transport through the nuclear pore complex (NPC); Belongs to the GLE1 family	0.996
NUP214	NXF1	ENSP00000352400	ENSP00000436679	Nuclear pore complex protein Nup214; May serve as a docking site in the receptor-mediated import of substrates across the nuclear pore complex; Nucleoporins	Nuclear RNA export factor 1; Involved in the nuclear export of mRNA species bearing retroviral constitutive transport elements (CTE) and in the export of mRNA from the nucleus to the cytoplasm (TAP/NFX1 pathway). The NXF1-NXT1 heterodimer is involved in the export of HSP70 mRNA in conjunction with ALYREF/THOC4 and THOC5 components of the TREX complex. ALYREF/THOC4-bound mRNA is thought to be transferred to the NXF1-NXT1 heterodimer for export	0.991
NUP214	NXF5	ENSP00000352400	ENSP00000426978	Nuclear pore complex protein Nup214; May serve as a docking site in the receptor-mediated import of substrates across the nuclear pore complex; Nucleoporins	Nuclear RNA export factor 5; Could be involved in the export of mRNA from the nucleus to the cytoplasm. Could also have a role in polarized cytoplasmic transport and localization of mRNA in neurons	0.783

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