LRRC49 protein (human) - STRING database

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LRRC49

Leucine-rich repeat-containing protein 49; Leucine rich repeat containing 49 (691 aa)

Predicted Functional Partners:

TPGS1

0.991

TTLL1

0.983

NICN1

0.982

TPGS2

0.981

C11orf49

0.914

KIAA1841

0.851

TBC1D19

0.843

CCDC148

0.768

THAP10

0.741

EIF3F

0.732

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C11orf49	EIF3F	ENSP00000367878	ENSP00000431800	UPF0705 protein C11orf49; Chromosome 11 open reading frame 49; Belongs to the UPF0705 family	Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2-GTP-methionyl-tRNAi and eIF-5 to form the 43S pre- initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...]	0.552
C11orf49	LRRC49	ENSP00000367878	ENSP00000453273	UPF0705 protein C11orf49; Chromosome 11 open reading frame 49; Belongs to the UPF0705 family	Leucine-rich repeat-containing protein 49; Leucine rich repeat containing 49	0.914
C11orf49	NICN1	ENSP00000367878	ENSP00000273598	UPF0705 protein C11orf49; Chromosome 11 open reading frame 49; Belongs to the UPF0705 family	Nicolin-1; Nicolin 1	0.835
C11orf49	TPGS2	ENSP00000367878	ENSP00000464780	UPF0705 protein C11orf49; Chromosome 11 open reading frame 49; Belongs to the UPF0705 family	Tubulin polyglutamylase complex subunit 2	0.857
C11orf49	TTLL1	ENSP00000367878	ENSP00000266254	UPF0705 protein C11orf49; Chromosome 11 open reading frame 49; Belongs to the UPF0705 family	Probable tubulin polyglutamylase TTLL1; Catalytic subunit of the neuronal tubulin polyglutamylase complex. Modifies alpha- and beta-tubulin, generating side chains of glutamate on the gamma-carboxyl groups of specific glutamate residues within the C-terminal tail of alpha- and beta-tubulin (By similarity); Tubulin tyrosine ligase family	0.822
CCDC148	LRRC49	ENSP00000283233	ENSP00000453273	Coiled-coil domain containing 148	Leucine-rich repeat-containing protein 49; Leucine rich repeat containing 49	0.768
EIF3F	C11orf49	ENSP00000431800	ENSP00000367878	Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2-GTP-methionyl-tRNAi and eIF-5 to form the 43S pre- initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...]	UPF0705 protein C11orf49; Chromosome 11 open reading frame 49; Belongs to the UPF0705 family	0.552
EIF3F	LRRC49	ENSP00000431800	ENSP00000453273	Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2-GTP-methionyl-tRNAi and eIF-5 to form the 43S pre- initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...]	Leucine-rich repeat-containing protein 49; Leucine rich repeat containing 49	0.732
EIF3F	TPGS1	ENSP00000431800	ENSP00000352265	Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2-GTP-methionyl-tRNAi and eIF-5 to form the 43S pre- initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...]	Tubulin polyglutamylase complex subunit 1; May act in the targeting of the tubulin polyglutamylase complex. Required for the development of the spermatid flagellum (By similarity)	0.552
KIAA1841	LRRC49	ENSP00000385579	ENSP00000453273	Uncharacterized protein KIAA1841; KIAA1841	Leucine-rich repeat-containing protein 49; Leucine rich repeat containing 49	0.851
KIAA1841	NICN1	ENSP00000385579	ENSP00000273598	Uncharacterized protein KIAA1841; KIAA1841	Nicolin-1; Nicolin 1	0.829
KIAA1841	TTLL1	ENSP00000385579	ENSP00000266254	Uncharacterized protein KIAA1841; KIAA1841	Probable tubulin polyglutamylase TTLL1; Catalytic subunit of the neuronal tubulin polyglutamylase complex. Modifies alpha- and beta-tubulin, generating side chains of glutamate on the gamma-carboxyl groups of specific glutamate residues within the C-terminal tail of alpha- and beta-tubulin (By similarity); Tubulin tyrosine ligase family	0.874
LRRC49	C11orf49	ENSP00000453273	ENSP00000367878	Leucine-rich repeat-containing protein 49; Leucine rich repeat containing 49	UPF0705 protein C11orf49; Chromosome 11 open reading frame 49; Belongs to the UPF0705 family	0.914
LRRC49	CCDC148	ENSP00000453273	ENSP00000283233	Leucine-rich repeat-containing protein 49; Leucine rich repeat containing 49	Coiled-coil domain containing 148	0.768
LRRC49	EIF3F	ENSP00000453273	ENSP00000431800	Leucine-rich repeat-containing protein 49; Leucine rich repeat containing 49	Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2-GTP-methionyl-tRNAi and eIF-5 to form the 43S pre- initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...]	0.732
LRRC49	KIAA1841	ENSP00000453273	ENSP00000385579	Leucine-rich repeat-containing protein 49; Leucine rich repeat containing 49	Uncharacterized protein KIAA1841; KIAA1841	0.851
LRRC49	NICN1	ENSP00000453273	ENSP00000273598	Leucine-rich repeat-containing protein 49; Leucine rich repeat containing 49	Nicolin-1; Nicolin 1	0.982
LRRC49	TBC1D19	ENSP00000453273	ENSP00000264866	Leucine-rich repeat-containing protein 49; Leucine rich repeat containing 49	TBC1 domain family member 19; May act as a GTPase-activating protein for Rab family protein(s)	0.843
LRRC49	THAP10	ENSP00000453273	ENSP00000249861	Leucine-rich repeat-containing protein 49; Leucine rich repeat containing 49	THAP domain containing 10	0.741
LRRC49	TPGS1	ENSP00000453273	ENSP00000352265	Leucine-rich repeat-containing protein 49; Leucine rich repeat containing 49	Tubulin polyglutamylase complex subunit 1; May act in the targeting of the tubulin polyglutamylase complex. Required for the development of the spermatid flagellum (By similarity)	0.991

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