node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AAGAB | AP2S1 | ENSP00000261880 | ENSP00000263270 | Alpha- and gamma-adaptin-binding protein p34; May be involved in endocytic recycling of growth factor receptors such as EGFR | AP-2 complex subunit sigma; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein Transport via Transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin- coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold b [...] | 0.572 |
AAGAB | C15orf57 | ENSP00000261880 | ENSP00000452773 | Alpha- and gamma-adaptin-binding protein p34; May be involved in endocytic recycling of growth factor receptors such as EGFR | Coiled-coil domain-containing protein 32; Chromosome 15 open reading frame 57 | 0.825 |
AP2S1 | AAGAB | ENSP00000263270 | ENSP00000261880 | AP-2 complex subunit sigma; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein Transport via Transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin- coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold b [...] | Alpha- and gamma-adaptin-binding protein p34; May be involved in endocytic recycling of growth factor receptors such as EGFR | 0.572 |
AP2S1 | C15orf57 | ENSP00000263270 | ENSP00000452773 | AP-2 complex subunit sigma; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein Transport via Transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin- coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold b [...] | Coiled-coil domain-containing protein 32; Chromosome 15 open reading frame 57 | 0.816 |
C15orf57 | AAGAB | ENSP00000452773 | ENSP00000261880 | Coiled-coil domain-containing protein 32; Chromosome 15 open reading frame 57 | Alpha- and gamma-adaptin-binding protein p34; May be involved in endocytic recycling of growth factor receptors such as EGFR | 0.825 |
C15orf57 | AP2S1 | ENSP00000452773 | ENSP00000263270 | Coiled-coil domain-containing protein 32; Chromosome 15 open reading frame 57 | AP-2 complex subunit sigma; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein Transport via Transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin- coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold b [...] | 0.816 |
C15orf57 | C1orf194 | ENSP00000452773 | ENSP00000358965 | Coiled-coil domain-containing protein 32; Chromosome 15 open reading frame 57 | Uncharacterized protein C1orf194; Chromosome 1 open reading frame 194 | 0.595 |
C15orf57 | CBX3 | ENSP00000452773 | ENSP00000336687 | Coiled-coil domain-containing protein 32; Chromosome 15 open reading frame 57 | Chromobox protein homolog 3; Seems to be involved in transcriptional silencing in heterochromatin-like complexes. Recognizes and binds histone H3 tails methylated at ’Lys-9’, leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. Contributes to the conversion of local chromatin to a heterochromatin-like repressive state through H3 ’Lys-9’ trimethylation, mediates the [...] | 0.676 |
C15orf57 | CDCP2 | ENSP00000452773 | ENSP00000360381 | Coiled-coil domain-containing protein 32; Chromosome 15 open reading frame 57 | CUB domain containing protein 2 | 0.581 |
C15orf57 | OR2W1 | ENSP00000452773 | ENSP00000366380 | Coiled-coil domain-containing protein 32; Chromosome 15 open reading frame 57 | Olfactory receptor 2W1; Odorant receptor; Olfactory receptors, family 2 | 0.518 |
C15orf57 | OR5T1 | ENSP00000452773 | ENSP00000323612 | Coiled-coil domain-containing protein 32; Chromosome 15 open reading frame 57 | Olfactory receptor 5T1; Odorant receptor; Olfactory receptors, family 5 | 0.548 |
C15orf57 | VWA3A | ENSP00000452773 | ENSP00000374049 | Coiled-coil domain-containing protein 32; Chromosome 15 open reading frame 57 | Von Willebrand factor A domain containing 3A | 0.529 |
C15orf57 | ZC2HC1C | ENSP00000452773 | ENSP00000435550 | Coiled-coil domain-containing protein 32; Chromosome 15 open reading frame 57 | Zinc finger C2HC-type containing 1C; Belongs to the ZC2HC1 family | 0.575 |
C15orf57 | ZNF518A | ENSP00000452773 | ENSP00000485614 | Coiled-coil domain-containing protein 32; Chromosome 15 open reading frame 57 | Zinc finger protein 518A; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.538 |
C1orf194 | C15orf57 | ENSP00000358965 | ENSP00000452773 | Uncharacterized protein C1orf194; Chromosome 1 open reading frame 194 | Coiled-coil domain-containing protein 32; Chromosome 15 open reading frame 57 | 0.595 |
C1orf194 | CBX3 | ENSP00000358965 | ENSP00000336687 | Uncharacterized protein C1orf194; Chromosome 1 open reading frame 194 | Chromobox protein homolog 3; Seems to be involved in transcriptional silencing in heterochromatin-like complexes. Recognizes and binds histone H3 tails methylated at ’Lys-9’, leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. Contributes to the conversion of local chromatin to a heterochromatin-like repressive state through H3 ’Lys-9’ trimethylation, mediates the [...] | 0.542 |
CBX3 | C15orf57 | ENSP00000336687 | ENSP00000452773 | Chromobox protein homolog 3; Seems to be involved in transcriptional silencing in heterochromatin-like complexes. Recognizes and binds histone H3 tails methylated at ’Lys-9’, leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. Contributes to the conversion of local chromatin to a heterochromatin-like repressive state through H3 ’Lys-9’ trimethylation, mediates the [...] | Coiled-coil domain-containing protein 32; Chromosome 15 open reading frame 57 | 0.676 |
CBX3 | C1orf194 | ENSP00000336687 | ENSP00000358965 | Chromobox protein homolog 3; Seems to be involved in transcriptional silencing in heterochromatin-like complexes. Recognizes and binds histone H3 tails methylated at ’Lys-9’, leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. Contributes to the conversion of local chromatin to a heterochromatin-like repressive state through H3 ’Lys-9’ trimethylation, mediates the [...] | Uncharacterized protein C1orf194; Chromosome 1 open reading frame 194 | 0.542 |
CDCP2 | C15orf57 | ENSP00000360381 | ENSP00000452773 | CUB domain containing protein 2 | Coiled-coil domain-containing protein 32; Chromosome 15 open reading frame 57 | 0.581 |
CDCP2 | ZNF518A | ENSP00000360381 | ENSP00000485614 | CUB domain containing protein 2 | Zinc finger protein 518A; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.630 |