POTEM protein (human) - STRING database

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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proteins of unknown 3D structure

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

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Score

POTEM

POTE ankyrin domain family member M (508 aa)

Predicted Functional Partners:

OR11H12

0.556

UBBP4

0.542

OR4M1

0.535

ENSG00000203546

0.528

SLC35G6

0.510

OR4Q3

0.473

CAPZB

0.464

AGAP10

0.450

CAP1

0.441

CAP2

0.441

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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structured XML interaction data, according to the 'PSI-MI' data standard

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... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGAP10	ENSG00000203546	ENSP00000392206	ENSP00000447056	ArfGAP with GTPase domain, ankyrin repeat and PH domain 10	Uncharacterized protein	0.557
AGAP10	POTEM	ENSP00000392206	ENSP00000450853	ArfGAP with GTPase domain, ankyrin repeat and PH domain 10	POTE ankyrin domain family member M	0.450
AGAP10	SLC35G6	ENSP00000392206	ENSP00000396523	ArfGAP with GTPase domain, ankyrin repeat and PH domain 10	Solute carrier family 35 member G6	0.540
AGAP10	UBBP4	ENSP00000392206	ENSP00000464265	ArfGAP with GTPase domain, ankyrin repeat and PH domain 10	Ubiquitin B pseudogene 4	0.543
CAP1	CAP2	ENSP00000361883	ENSP00000229922	Adenylyl cyclase-associated protein 1; Directly regulates filament dynamics and has been implicated in a number of complex developmental and morphological processes, including mRNA localization and the establishment of cell polarity; Belongs to the CAP family	Adenylyl cyclase-associated protein 2; May have a regulatory bifunctional role; Belongs to the CAP family	0.926
CAP1	CAPZB	ENSP00000361883	ENSP00000401010	Adenylyl cyclase-associated protein 1; Directly regulates filament dynamics and has been implicated in a number of complex developmental and morphological processes, including mRNA localization and the establishment of cell polarity; Belongs to the CAP family	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. Plays a role in the regulation of cell morphology and cytoskeletal organization	0.577
CAP1	POTEM	ENSP00000361883	ENSP00000450853	Adenylyl cyclase-associated protein 1; Directly regulates filament dynamics and has been implicated in a number of complex developmental and morphological processes, including mRNA localization and the establishment of cell polarity; Belongs to the CAP family	POTE ankyrin domain family member M	0.441
CAP2	CAP1	ENSP00000229922	ENSP00000361883	Adenylyl cyclase-associated protein 2; May have a regulatory bifunctional role; Belongs to the CAP family	Adenylyl cyclase-associated protein 1; Directly regulates filament dynamics and has been implicated in a number of complex developmental and morphological processes, including mRNA localization and the establishment of cell polarity; Belongs to the CAP family	0.926
CAP2	CAPZB	ENSP00000229922	ENSP00000401010	Adenylyl cyclase-associated protein 2; May have a regulatory bifunctional role; Belongs to the CAP family	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. Plays a role in the regulation of cell morphology and cytoskeletal organization	0.449
CAP2	POTEM	ENSP00000229922	ENSP00000450853	Adenylyl cyclase-associated protein 2; May have a regulatory bifunctional role; Belongs to the CAP family	POTE ankyrin domain family member M	0.441
CAPZB	CAP1	ENSP00000401010	ENSP00000361883	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. Plays a role in the regulation of cell morphology and cytoskeletal organization	Adenylyl cyclase-associated protein 1; Directly regulates filament dynamics and has been implicated in a number of complex developmental and morphological processes, including mRNA localization and the establishment of cell polarity; Belongs to the CAP family	0.577
CAPZB	CAP2	ENSP00000401010	ENSP00000229922	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. Plays a role in the regulation of cell morphology and cytoskeletal organization	Adenylyl cyclase-associated protein 2; May have a regulatory bifunctional role; Belongs to the CAP family	0.449
CAPZB	POTEM	ENSP00000401010	ENSP00000450853	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. Plays a role in the regulation of cell morphology and cytoskeletal organization	POTE ankyrin domain family member M	0.464
ENSG00000203546	AGAP10	ENSP00000447056	ENSP00000392206	Uncharacterized protein	ArfGAP with GTPase domain, ankyrin repeat and PH domain 10	0.557
ENSG00000203546	POTEM	ENSP00000447056	ENSP00000450853	Uncharacterized protein	POTE ankyrin domain family member M	0.528
ENSG00000203546	SLC35G6	ENSP00000447056	ENSP00000396523	Uncharacterized protein	Solute carrier family 35 member G6	0.654
ENSG00000203546	UBBP4	ENSP00000447056	ENSP00000464265	Uncharacterized protein	Ubiquitin B pseudogene 4	0.649
OR11H12	POTEM	ENSP00000449002	ENSP00000450853	Olfactory receptor 11H12; Odorant receptor; Olfactory receptors, family 11	POTE ankyrin domain family member M	0.556
OR4M1	POTEM	ENSP00000319654	ENSP00000450853	Olfactory receptor 4M1; Odorant receptor; Olfactory receptors, family 4	POTE ankyrin domain family member M	0.535
OR4Q3	POTEM	ENSP00000330049	ENSP00000450853	Olfactory receptor 4Q3; Odorant receptor; Olfactory receptors, family 4	POTE ankyrin domain family member M	0.473

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