GLIPR1L2 protein (human) - STRING database

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GLIPR1L2

GLIPR1-like protein 2; GLI pathogenesis related family 1; Belongs to the CRISP family (344 aa)

Predicted Functional Partners:

RMND5A

0.813

ZMYND19

0.710

RANBP10

0.644

MAEA

0.626

RANBP9

0.607

ARMC8

0.547

MKLN1

0.547

GID4

0.541

KRR1

0.526

C3orf62

0.515

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARMC8	GID4	ENSP00000420333	ENSP00000268719	Armadillo repeat containing 8	Glucose-induced degradation protein 4 homolog; GID complex subunit 4 homolog; Belongs to the GID4/VID24 family	0.914
ARMC8	GLIPR1L2	ENSP00000420333	ENSP00000448248	Armadillo repeat containing 8	GLIPR1-like protein 2; GLI pathogenesis related family 1; Belongs to the CRISP family	0.547
ARMC8	MAEA	ENSP00000420333	ENSP00000302830	Armadillo repeat containing 8	Macrophage erythroblast attacher; Plays a role in erythroblast enucleation and in the development of the mature macrophages. Mediates the attachment of erythroid cell to mature macrophages, in correlation with the presence of MAEA at cell surface of mature macrophages; This MAEA- mediated contact inhibits erythroid cells apoptosis. Participates in erythroblastic island formation, which is the functional unit of definitive erythropoiesis. Associates with F-actin to regulate actin distribution in erythroblasts and macrophages. May contribute to nuclear architecture and cells division eve [...]	0.897
ARMC8	MKLN1	ENSP00000420333	ENSP00000323527	Armadillo repeat containing 8	Muskelin; Acts as a mediator of cell spreading and cytoskeletal responses to the extracellular matrix component THBS1; CTLH complex	0.796
ARMC8	RANBP10	ENSP00000420333	ENSP00000316589	Armadillo repeat containing 8	Ran-binding protein 10; Acts as a guanine nucleotide exchange factor (GEF) for RAN GTPase (By similarity). May play an essential role in hemostasis and in maintaining microtubule dynamics with respect to both platelet shape and function (By similarity). May act as an adapter protein to couple membrane receptors to intracellular signaling pathways. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but does not affect estrogen- induced transactivation. In contrast to RANBP9, does not interact with Sos [...]	0.803
ARMC8	RANBP9	ENSP00000420333	ENSP00000011619	Armadillo repeat containing 8	Ran-binding protein 9; May act as an adapter protein to couple membrane receptors to intracellular signaling pathways. May be involved in signaling of ITGB2/LFA-1 and other integrins. Enhances HGF-MET signaling by recruiting Sos and activating the Ras pathway. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but not affect estrogen-induced transactivation. Stabilizes TP73 isoform Alpha, probably by inhibiting its ubiquitination, and increases its proapoptotic activity. Inhibits the kinase activity o [...]	0.895
ARMC8	RMND5A	ENSP00000420333	ENSP00000283632	Armadillo repeat containing 8	Protein RMD5 homolog A; Required for meiotic nuclear division 5 homolog A; CTLH complex	0.964
C3orf62	GLIPR1L2	ENSP00000341139	ENSP00000448248	Uncharacterized protein C3orf62; Chromosome 3 open reading frame 62	GLIPR1-like protein 2; GLI pathogenesis related family 1; Belongs to the CRISP family	0.515
GID4	ARMC8	ENSP00000268719	ENSP00000420333	Glucose-induced degradation protein 4 homolog; GID complex subunit 4 homolog; Belongs to the GID4/VID24 family	Armadillo repeat containing 8	0.914
GID4	GLIPR1L2	ENSP00000268719	ENSP00000448248	Glucose-induced degradation protein 4 homolog; GID complex subunit 4 homolog; Belongs to the GID4/VID24 family	GLIPR1-like protein 2; GLI pathogenesis related family 1; Belongs to the CRISP family	0.541
GID4	MAEA	ENSP00000268719	ENSP00000302830	Glucose-induced degradation protein 4 homolog; GID complex subunit 4 homolog; Belongs to the GID4/VID24 family	Macrophage erythroblast attacher; Plays a role in erythroblast enucleation and in the development of the mature macrophages. Mediates the attachment of erythroid cell to mature macrophages, in correlation with the presence of MAEA at cell surface of mature macrophages; This MAEA- mediated contact inhibits erythroid cells apoptosis. Participates in erythroblastic island formation, which is the functional unit of definitive erythropoiesis. Associates with F-actin to regulate actin distribution in erythroblasts and macrophages. May contribute to nuclear architecture and cells division eve [...]	0.855
GID4	MKLN1	ENSP00000268719	ENSP00000323527	Glucose-induced degradation protein 4 homolog; GID complex subunit 4 homolog; Belongs to the GID4/VID24 family	Muskelin; Acts as a mediator of cell spreading and cytoskeletal responses to the extracellular matrix component THBS1; CTLH complex	0.717
GID4	RANBP10	ENSP00000268719	ENSP00000316589	Glucose-induced degradation protein 4 homolog; GID complex subunit 4 homolog; Belongs to the GID4/VID24 family	Ran-binding protein 10; Acts as a guanine nucleotide exchange factor (GEF) for RAN GTPase (By similarity). May play an essential role in hemostasis and in maintaining microtubule dynamics with respect to both platelet shape and function (By similarity). May act as an adapter protein to couple membrane receptors to intracellular signaling pathways. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but does not affect estrogen- induced transactivation. In contrast to RANBP9, does not interact with Sos [...]	0.688
GID4	RANBP9	ENSP00000268719	ENSP00000011619	Glucose-induced degradation protein 4 homolog; GID complex subunit 4 homolog; Belongs to the GID4/VID24 family	Ran-binding protein 9; May act as an adapter protein to couple membrane receptors to intracellular signaling pathways. May be involved in signaling of ITGB2/LFA-1 and other integrins. Enhances HGF-MET signaling by recruiting Sos and activating the Ras pathway. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but not affect estrogen-induced transactivation. Stabilizes TP73 isoform Alpha, probably by inhibiting its ubiquitination, and increases its proapoptotic activity. Inhibits the kinase activity o [...]	0.828
GID4	RMND5A	ENSP00000268719	ENSP00000283632	Glucose-induced degradation protein 4 homolog; GID complex subunit 4 homolog; Belongs to the GID4/VID24 family	Protein RMD5 homolog A; Required for meiotic nuclear division 5 homolog A; CTLH complex	0.971
GLIPR1L2	ARMC8	ENSP00000448248	ENSP00000420333	GLIPR1-like protein 2; GLI pathogenesis related family 1; Belongs to the CRISP family	Armadillo repeat containing 8	0.547
GLIPR1L2	C3orf62	ENSP00000448248	ENSP00000341139	GLIPR1-like protein 2; GLI pathogenesis related family 1; Belongs to the CRISP family	Uncharacterized protein C3orf62; Chromosome 3 open reading frame 62	0.515
GLIPR1L2	GID4	ENSP00000448248	ENSP00000268719	GLIPR1-like protein 2; GLI pathogenesis related family 1; Belongs to the CRISP family	Glucose-induced degradation protein 4 homolog; GID complex subunit 4 homolog; Belongs to the GID4/VID24 family	0.541
GLIPR1L2	KRR1	ENSP00000448248	ENSP00000229214	GLIPR1-like protein 2; GLI pathogenesis related family 1; Belongs to the CRISP family	KRR1 small subunit processome component homolog; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly (By similarity)	0.526
GLIPR1L2	MAEA	ENSP00000448248	ENSP00000302830	GLIPR1-like protein 2; GLI pathogenesis related family 1; Belongs to the CRISP family	Macrophage erythroblast attacher; Plays a role in erythroblast enucleation and in the development of the mature macrophages. Mediates the attachment of erythroid cell to mature macrophages, in correlation with the presence of MAEA at cell surface of mature macrophages; This MAEA- mediated contact inhibits erythroid cells apoptosis. Participates in erythroblastic island formation, which is the functional unit of definitive erythropoiesis. Associates with F-actin to regulate actin distribution in erythroblasts and macrophages. May contribute to nuclear architecture and cells division eve [...]	0.626

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