node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ARMCX5 | BEX5 | ENSP00000474720 | ENSP00000446054 | Armadillo repeat containing, X-linked 5 | Protein BEX5; Brain expressed X-linked family; Belongs to the BEX family | 0.531 |
ARMCX5 | NXF3 | ENSP00000474720 | ENSP00000378504 | Armadillo repeat containing, X-linked 5 | Nuclear RNA export factor 3; May function as a tissue-specific nuclear mRNA export factor | 0.573 |
ARMCX5 | TCEAL6 | ENSP00000474720 | ENSP00000361860 | Armadillo repeat containing, X-linked 5 | Transcription elongation factor A like family | 0.532 |
BEX5 | ARMCX5 | ENSP00000446054 | ENSP00000474720 | Protein BEX5; Brain expressed X-linked family; Belongs to the BEX family | Armadillo repeat containing, X-linked 5 | 0.531 |
BEX5 | HS3ST4 | ENSP00000446054 | ENSP00000330606 | Protein BEX5; Brain expressed X-linked family; Belongs to the BEX family | Heparan sulfate glucosamine 3-O-sulfotransferase 4; Sulfotransferase that utilizes 3’-phospho-5’-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to an N- unsubstituted glucosamine linked to a 2-O-sulfo iduronic acid unit on heparan sulfate. Unlike 3-OST-1, does not convert non- anticoagulant heparan sulfate to anticoagulant heparan sulfate (By similarity) | 0.657 |
BEX5 | KISS1 | ENSP00000446054 | ENSP00000356162 | Protein BEX5; Brain expressed X-linked family; Belongs to the BEX family | Metastasis-suppressor KiSS-1; Metastasis suppressor protein in malignant melanomas and in some breast cancers. May regulate events downstream of cell- matrix adhesion, perhaps involving cytoskeletal reorganization. Generates a C-terminally amidated peptide, metastin which functions as the endogenous ligand of the G-protein coupled receptor GPR54. Activation of the receptor inhibits cell proliferation and cell migration, key characteristics of tumor metastasis. Kp-10 is a decapeptide derived from the primary translation product, isolated in conditioned medium of first trimester trophobl [...] | 0.567 |
BEX5 | LINGO2 | ENSP00000446054 | ENSP00000369328 | Protein BEX5; Brain expressed X-linked family; Belongs to the BEX family | Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2; Leucine rich repeat and Ig domain containing 2 | 0.635 |
BEX5 | NXF3 | ENSP00000446054 | ENSP00000378504 | Protein BEX5; Brain expressed X-linked family; Belongs to the BEX family | Nuclear RNA export factor 3; May function as a tissue-specific nuclear mRNA export factor | 0.537 |
BEX5 | RAB40A | ENSP00000446054 | ENSP00000361716 | Protein BEX5; Brain expressed X-linked family; Belongs to the BEX family | Ras-related protein Rab-40A; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins; Belongs to the small GTPase superfamily. Rab family | 0.673 |
BEX5 | TCEAL2 | ENSP00000446054 | ENSP00000361866 | Protein BEX5; Brain expressed X-linked family; Belongs to the BEX family | Transcription elongation factor A protein-like 2; May be involved in transcriptional regulation; Transcription elongation factor A like family | 0.673 |
BEX5 | TCEAL3 | ENSP00000446054 | ENSP00000361711 | Protein BEX5; Brain expressed X-linked family; Belongs to the BEX family | Transcription elongation factor A protein-like 3; May be involved in transcriptional regulation; Transcription elongation factor A like family | 0.701 |
BEX5 | TCEAL5 | ENSP00000446054 | ENSP00000361765 | Protein BEX5; Brain expressed X-linked family; Belongs to the BEX family | Transcription elongation factor A protein-like 5; May be involved in transcriptional regulation; Transcription elongation factor A like family | 0.749 |
BEX5 | TCEAL6 | ENSP00000446054 | ENSP00000361860 | Protein BEX5; Brain expressed X-linked family; Belongs to the BEX family | Transcription elongation factor A like family | 0.698 |
HS3ST4 | BEX5 | ENSP00000330606 | ENSP00000446054 | Heparan sulfate glucosamine 3-O-sulfotransferase 4; Sulfotransferase that utilizes 3’-phospho-5’-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to an N- unsubstituted glucosamine linked to a 2-O-sulfo iduronic acid unit on heparan sulfate. Unlike 3-OST-1, does not convert non- anticoagulant heparan sulfate to anticoagulant heparan sulfate (By similarity) | Protein BEX5; Brain expressed X-linked family; Belongs to the BEX family | 0.657 |
HS3ST4 | KISS1 | ENSP00000330606 | ENSP00000356162 | Heparan sulfate glucosamine 3-O-sulfotransferase 4; Sulfotransferase that utilizes 3’-phospho-5’-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to an N- unsubstituted glucosamine linked to a 2-O-sulfo iduronic acid unit on heparan sulfate. Unlike 3-OST-1, does not convert non- anticoagulant heparan sulfate to anticoagulant heparan sulfate (By similarity) | Metastasis-suppressor KiSS-1; Metastasis suppressor protein in malignant melanomas and in some breast cancers. May regulate events downstream of cell- matrix adhesion, perhaps involving cytoskeletal reorganization. Generates a C-terminally amidated peptide, metastin which functions as the endogenous ligand of the G-protein coupled receptor GPR54. Activation of the receptor inhibits cell proliferation and cell migration, key characteristics of tumor metastasis. Kp-10 is a decapeptide derived from the primary translation product, isolated in conditioned medium of first trimester trophobl [...] | 0.565 |
HS3ST4 | LINGO2 | ENSP00000330606 | ENSP00000369328 | Heparan sulfate glucosamine 3-O-sulfotransferase 4; Sulfotransferase that utilizes 3’-phospho-5’-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to an N- unsubstituted glucosamine linked to a 2-O-sulfo iduronic acid unit on heparan sulfate. Unlike 3-OST-1, does not convert non- anticoagulant heparan sulfate to anticoagulant heparan sulfate (By similarity) | Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2; Leucine rich repeat and Ig domain containing 2 | 0.653 |
KISS1 | BEX5 | ENSP00000356162 | ENSP00000446054 | Metastasis-suppressor KiSS-1; Metastasis suppressor protein in malignant melanomas and in some breast cancers. May regulate events downstream of cell- matrix adhesion, perhaps involving cytoskeletal reorganization. Generates a C-terminally amidated peptide, metastin which functions as the endogenous ligand of the G-protein coupled receptor GPR54. Activation of the receptor inhibits cell proliferation and cell migration, key characteristics of tumor metastasis. Kp-10 is a decapeptide derived from the primary translation product, isolated in conditioned medium of first trimester trophobl [...] | Protein BEX5; Brain expressed X-linked family; Belongs to the BEX family | 0.567 |
KISS1 | HS3ST4 | ENSP00000356162 | ENSP00000330606 | Metastasis-suppressor KiSS-1; Metastasis suppressor protein in malignant melanomas and in some breast cancers. May regulate events downstream of cell- matrix adhesion, perhaps involving cytoskeletal reorganization. Generates a C-terminally amidated peptide, metastin which functions as the endogenous ligand of the G-protein coupled receptor GPR54. Activation of the receptor inhibits cell proliferation and cell migration, key characteristics of tumor metastasis. Kp-10 is a decapeptide derived from the primary translation product, isolated in conditioned medium of first trimester trophobl [...] | Heparan sulfate glucosamine 3-O-sulfotransferase 4; Sulfotransferase that utilizes 3’-phospho-5’-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to an N- unsubstituted glucosamine linked to a 2-O-sulfo iduronic acid unit on heparan sulfate. Unlike 3-OST-1, does not convert non- anticoagulant heparan sulfate to anticoagulant heparan sulfate (By similarity) | 0.565 |
KISS1 | LINGO2 | ENSP00000356162 | ENSP00000369328 | Metastasis-suppressor KiSS-1; Metastasis suppressor protein in malignant melanomas and in some breast cancers. May regulate events downstream of cell- matrix adhesion, perhaps involving cytoskeletal reorganization. Generates a C-terminally amidated peptide, metastin which functions as the endogenous ligand of the G-protein coupled receptor GPR54. Activation of the receptor inhibits cell proliferation and cell migration, key characteristics of tumor metastasis. Kp-10 is a decapeptide derived from the primary translation product, isolated in conditioned medium of first trimester trophobl [...] | Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2; Leucine rich repeat and Ig domain containing 2 | 0.569 |
LINGO2 | BEX5 | ENSP00000369328 | ENSP00000446054 | Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2; Leucine rich repeat and Ig domain containing 2 | Protein BEX5; Brain expressed X-linked family; Belongs to the BEX family | 0.635 |