| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CHERP | ERH | ENSP00000439856 | ENSP00000451080 | Calcium homeostasis endoplasmic reticulum protein; Involved in calcium homeostasis, growth and proliferation; G-patch domain containing | Enhancer of rudimentary homolog; May have a role in the cell cycle; Belongs to the E(R) family | 0.484 |
| CHERP | PHF3 | ENSP00000439856 | ENSP00000262043 | Calcium homeostasis endoplasmic reticulum protein; Involved in calcium homeostasis, growth and proliferation; G-patch domain containing | PHD finger protein 3 | 0.444 |
| CHERP | RAP2C | ENSP00000439856 | ENSP00000340274 | Calcium homeostasis endoplasmic reticulum protein; Involved in calcium homeostasis, growth and proliferation; G-patch domain containing | Ras-related protein Rap-2c; Small GTP-binding protein which cycles between a GDP- bound inactive and a GTP-bound active form. May play a role in cytoskeletal rearrangements and regulate cell spreading through activation of the effector TNIK. May play a role in SRE-mediated gene transcription; RAS type GTPase family | 0.404 |
| CHERP | RNF26 | ENSP00000439856 | ENSP00000312439 | Calcium homeostasis endoplasmic reticulum protein; Involved in calcium homeostasis, growth and proliferation; G-patch domain containing | E3 ubiquitin-protein ligase RNF26; E3 ubiquitin-protein ligase that plays a key role in endosome organization by retaining vesicles in the perinuclear cloud. Acts as a platform for perinuclear positioning of the endosomal system by mediating ubiquitination of SQSTM1. Ubiquitinated SQSTM1 attracts specific vesicle-associated adapters, forming a molecular bridge that restrains cognate vesicles in the perinuclear region and organizes the endosomal pathway for efficient cargo transport. Also acts as a regulator of type I interferon production in response to viral infection by mediating the [...] | 0.551 |
| CHERP | UBL3 | ENSP00000439856 | ENSP00000370055 | Calcium homeostasis endoplasmic reticulum protein; Involved in calcium homeostasis, growth and proliferation; G-patch domain containing | Ubiquitin-like protein 3; Ubiquitin like 3 | 0.446 |
| CHERP | ZNF324 | ENSP00000439856 | ENSP00000444812 | Calcium homeostasis endoplasmic reticulum protein; Involved in calcium homeostasis, growth and proliferation; G-patch domain containing | Zinc finger protein 324A; May be involved in transcriptional regulation. May be involved in regulation of cell proliferation; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.593 |
| CLIC3 | RNF26 | ENSP00000419378 | ENSP00000312439 | Chloride intracellular channel protein 3; Can insert into membranes and form chloride ion channels. May participate in cellular growth control; Belongs to the chloride channel CLIC family | E3 ubiquitin-protein ligase RNF26; E3 ubiquitin-protein ligase that plays a key role in endosome organization by retaining vesicles in the perinuclear cloud. Acts as a platform for perinuclear positioning of the endosomal system by mediating ubiquitination of SQSTM1. Ubiquitinated SQSTM1 attracts specific vesicle-associated adapters, forming a molecular bridge that restrains cognate vesicles in the perinuclear region and organizes the endosomal pathway for efficient cargo transport. Also acts as a regulator of type I interferon production in response to viral infection by mediating the [...] | 0.400 |
| CLIC3 | ZNF324 | ENSP00000419378 | ENSP00000444812 | Chloride intracellular channel protein 3; Can insert into membranes and form chloride ion channels. May participate in cellular growth control; Belongs to the chloride channel CLIC family | Zinc finger protein 324A; May be involved in transcriptional regulation. May be involved in regulation of cell proliferation; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.477 |
| ERH | CHERP | ENSP00000451080 | ENSP00000439856 | Enhancer of rudimentary homolog; May have a role in the cell cycle; Belongs to the E(R) family | Calcium homeostasis endoplasmic reticulum protein; Involved in calcium homeostasis, growth and proliferation; G-patch domain containing | 0.484 |
| ERH | RNF26 | ENSP00000451080 | ENSP00000312439 | Enhancer of rudimentary homolog; May have a role in the cell cycle; Belongs to the E(R) family | E3 ubiquitin-protein ligase RNF26; E3 ubiquitin-protein ligase that plays a key role in endosome organization by retaining vesicles in the perinuclear cloud. Acts as a platform for perinuclear positioning of the endosomal system by mediating ubiquitination of SQSTM1. Ubiquitinated SQSTM1 attracts specific vesicle-associated adapters, forming a molecular bridge that restrains cognate vesicles in the perinuclear region and organizes the endosomal pathway for efficient cargo transport. Also acts as a regulator of type I interferon production in response to viral infection by mediating the [...] | 0.437 |
| ERH | ZNF324 | ENSP00000451080 | ENSP00000444812 | Enhancer of rudimentary homolog; May have a role in the cell cycle; Belongs to the E(R) family | Zinc finger protein 324A; May be involved in transcriptional regulation. May be involved in regulation of cell proliferation; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.484 |
| OGFR | RNF26 | ENSP00000290291 | ENSP00000312439 | Opioid growth factor receptor; Receptor for opioid growth factor (OGF), also known as Met-enkephalin. Seems to be involved in growth regulation | E3 ubiquitin-protein ligase RNF26; E3 ubiquitin-protein ligase that plays a key role in endosome organization by retaining vesicles in the perinuclear cloud. Acts as a platform for perinuclear positioning of the endosomal system by mediating ubiquitination of SQSTM1. Ubiquitinated SQSTM1 attracts specific vesicle-associated adapters, forming a molecular bridge that restrains cognate vesicles in the perinuclear region and organizes the endosomal pathway for efficient cargo transport. Also acts as a regulator of type I interferon production in response to viral infection by mediating the [...] | 0.413 |
| OGFR | ZNF324 | ENSP00000290291 | ENSP00000444812 | Opioid growth factor receptor; Receptor for opioid growth factor (OGF), also known as Met-enkephalin. Seems to be involved in growth regulation | Zinc finger protein 324A; May be involved in transcriptional regulation. May be involved in regulation of cell proliferation; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.510 |
| PHF3 | CHERP | ENSP00000262043 | ENSP00000439856 | PHD finger protein 3 | Calcium homeostasis endoplasmic reticulum protein; Involved in calcium homeostasis, growth and proliferation; G-patch domain containing | 0.444 |
| PHF3 | RNF26 | ENSP00000262043 | ENSP00000312439 | PHD finger protein 3 | E3 ubiquitin-protein ligase RNF26; E3 ubiquitin-protein ligase that plays a key role in endosome organization by retaining vesicles in the perinuclear cloud. Acts as a platform for perinuclear positioning of the endosomal system by mediating ubiquitination of SQSTM1. Ubiquitinated SQSTM1 attracts specific vesicle-associated adapters, forming a molecular bridge that restrains cognate vesicles in the perinuclear region and organizes the endosomal pathway for efficient cargo transport. Also acts as a regulator of type I interferon production in response to viral infection by mediating the [...] | 0.501 |
| PHF3 | UBL3 | ENSP00000262043 | ENSP00000370055 | PHD finger protein 3 | Ubiquitin-like protein 3; Ubiquitin like 3 | 0.416 |
| PHF3 | ZNF324 | ENSP00000262043 | ENSP00000444812 | PHD finger protein 3 | Zinc finger protein 324A; May be involved in transcriptional regulation. May be involved in regulation of cell proliferation; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.526 |
| PHLDB3 | ZNF324 | ENSP00000292140 | ENSP00000444812 | Pleckstrin homology like domain family B member 3 | Zinc finger protein 324A; May be involved in transcriptional regulation. May be involved in regulation of cell proliferation; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.589 |
| RAP2C | CHERP | ENSP00000340274 | ENSP00000439856 | Ras-related protein Rap-2c; Small GTP-binding protein which cycles between a GDP- bound inactive and a GTP-bound active form. May play a role in cytoskeletal rearrangements and regulate cell spreading through activation of the effector TNIK. May play a role in SRE-mediated gene transcription; RAS type GTPase family | Calcium homeostasis endoplasmic reticulum protein; Involved in calcium homeostasis, growth and proliferation; G-patch domain containing | 0.404 |
| RAP2C | RNF26 | ENSP00000340274 | ENSP00000312439 | Ras-related protein Rap-2c; Small GTP-binding protein which cycles between a GDP- bound inactive and a GTP-bound active form. May play a role in cytoskeletal rearrangements and regulate cell spreading through activation of the effector TNIK. May play a role in SRE-mediated gene transcription; RAS type GTPase family | E3 ubiquitin-protein ligase RNF26; E3 ubiquitin-protein ligase that plays a key role in endosome organization by retaining vesicles in the perinuclear cloud. Acts as a platform for perinuclear positioning of the endosomal system by mediating ubiquitination of SQSTM1. Ubiquitinated SQSTM1 attracts specific vesicle-associated adapters, forming a molecular bridge that restrains cognate vesicles in the perinuclear region and organizes the endosomal pathway for efficient cargo transport. Also acts as a regulator of type I interferon production in response to viral infection by mediating the [...] | 0.426 |
