GLB1L2 protein (human) - STRING database

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GLB1L2

Beta-galactosidase-1-like protein 2; Galactosidase beta 1 like 2 (636 aa)

Predicted Functional Partners:

ECT2L

0.735

NOSTRIN

0.731

MARS2

0.731

KIF18B

0.656

GOLPH3L

0.638

CDC42EP5

0.619

MAGI3

0.604

PABPN1L

0.553

YPEL1

0.532

KIF19

0.525

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC42EP5	GLB1L2	ENSP00000301200	ENSP00000444628	Cdc42 effector protein 5; Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts. Inhibits MAPK8 independently of CDC42 binding. Controls septin organization and this effect is negatively regulated by CDC42 (By similarity); Belongs to the BORG/CEP family	Beta-galactosidase-1-like protein 2; Galactosidase beta 1 like 2	0.619
CDC42EP5	YPEL1	ENSP00000301200	ENSP00000342832	Cdc42 effector protein 5; Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts. Inhibits MAPK8 independently of CDC42 binding. Controls septin organization and this effect is negatively regulated by CDC42 (By similarity); Belongs to the BORG/CEP family	Protein yippee-like 1; May play a role in epithelioid conversion of fibroblasts; Yippee like family	0.525
ECT2L	GLB1L2	ENSP00000442307	ENSP00000444628	Epithelial cell-transforming sequence 2 oncogene-like; May act as a guanine nucleotide exchange factor (GEF); F-boxes other	Beta-galactosidase-1-like protein 2; Galactosidase beta 1 like 2	0.735
ECT2L	KIF18B	ENSP00000442307	ENSP00000465992	Epithelial cell-transforming sequence 2 oncogene-like; May act as a guanine nucleotide exchange factor (GEF); F-boxes other	Kinesin-like protein KIF18B; In complex with KIF2C, constitutes the major microtubule plus-end depolymerizing activity in mitotic cells. Its major role may be to transport KIF2C and/or MAPRE1 along microtubules; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family	0.533
ECT2L	KIF19	ENSP00000442307	ENSP00000374566	Epithelial cell-transforming sequence 2 oncogene-like; May act as a guanine nucleotide exchange factor (GEF); F-boxes other	Kinesin-like protein KIF19; Plus end-directed microtubule-dependent motor protein that regulates the length of motile cilia by mediating depolymerization of microtubules at ciliary tips; Kinesins	0.521
ECT2L	MAGI3	ENSP00000442307	ENSP00000304604	Epithelial cell-transforming sequence 2 oncogene-like; May act as a guanine nucleotide exchange factor (GEF); F-boxes other	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3; Acts as a scaffolding protein at cell-cell junctions, thereby regulating various cellular and signaling processes. Cooperates with PTEN to modulate the kinase activity of AKT1. Its interaction with PTPRB and tyrosine phosphorylated proteins suggests that it may link receptor tyrosine phosphatase with its substrates at the plasma membrane. In polarized epithelial cells, involved in efficient trafficking of TGFA to the cell surface. Regulates the ability of LPAR2 to activate ERK and RhoA pathways. Regulates the [...]	0.478
GLB1L2	CDC42EP5	ENSP00000444628	ENSP00000301200	Beta-galactosidase-1-like protein 2; Galactosidase beta 1 like 2	Cdc42 effector protein 5; Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts. Inhibits MAPK8 independently of CDC42 binding. Controls septin organization and this effect is negatively regulated by CDC42 (By similarity); Belongs to the BORG/CEP family	0.619
GLB1L2	ECT2L	ENSP00000444628	ENSP00000442307	Beta-galactosidase-1-like protein 2; Galactosidase beta 1 like 2	Epithelial cell-transforming sequence 2 oncogene-like; May act as a guanine nucleotide exchange factor (GEF); F-boxes other	0.735
GLB1L2	GOLPH3L	ENSP00000444628	ENSP00000271732	Beta-galactosidase-1-like protein 2; Galactosidase beta 1 like 2	Golgi phosphoprotein 3-like; Phosphatidylinositol-4-phosphate-binding protein that may antagonize the action of GOLPH3 which is required for the process of vesicle budding at the Golgi and anterograde transport to the plasma membrane	0.638
GLB1L2	KIF18B	ENSP00000444628	ENSP00000465992	Beta-galactosidase-1-like protein 2; Galactosidase beta 1 like 2	Kinesin-like protein KIF18B; In complex with KIF2C, constitutes the major microtubule plus-end depolymerizing activity in mitotic cells. Its major role may be to transport KIF2C and/or MAPRE1 along microtubules; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family	0.656
GLB1L2	KIF19	ENSP00000444628	ENSP00000374566	Beta-galactosidase-1-like protein 2; Galactosidase beta 1 like 2	Kinesin-like protein KIF19; Plus end-directed microtubule-dependent motor protein that regulates the length of motile cilia by mediating depolymerization of microtubules at ciliary tips; Kinesins	0.525
GLB1L2	MAGI3	ENSP00000444628	ENSP00000304604	Beta-galactosidase-1-like protein 2; Galactosidase beta 1 like 2	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3; Acts as a scaffolding protein at cell-cell junctions, thereby regulating various cellular and signaling processes. Cooperates with PTEN to modulate the kinase activity of AKT1. Its interaction with PTPRB and tyrosine phosphorylated proteins suggests that it may link receptor tyrosine phosphatase with its substrates at the plasma membrane. In polarized epithelial cells, involved in efficient trafficking of TGFA to the cell surface. Regulates the ability of LPAR2 to activate ERK and RhoA pathways. Regulates the [...]	0.604
GLB1L2	MARS2	ENSP00000444628	ENSP00000282276	Beta-galactosidase-1-like protein 2; Galactosidase beta 1 like 2	Methionine--tRNA ligase, mitochondrial; methionyl-tRNA synthetase 2, mitochondrial; Aminoacyl tRNA synthetases, Class I	0.731
GLB1L2	NOSTRIN	ENSP00000444628	ENSP00000394051	Beta-galactosidase-1-like protein 2; Galactosidase beta 1 like 2	Nostrin; Nitric oxide synthase trafficking; F-BAR domain containing	0.731
GLB1L2	PABPN1L	ENSP00000444628	ENSP00000408598	Beta-galactosidase-1-like protein 2; Galactosidase beta 1 like 2	Embryonic polyadenylate-binding protein 2; Binds the poly(A) tail of mRNA; RNA binding motif containing	0.553
GLB1L2	YPEL1	ENSP00000444628	ENSP00000342832	Beta-galactosidase-1-like protein 2; Galactosidase beta 1 like 2	Protein yippee-like 1; May play a role in epithelioid conversion of fibroblasts; Yippee like family	0.532
GOLPH3L	GLB1L2	ENSP00000271732	ENSP00000444628	Golgi phosphoprotein 3-like; Phosphatidylinositol-4-phosphate-binding protein that may antagonize the action of GOLPH3 which is required for the process of vesicle budding at the Golgi and anterograde transport to the plasma membrane	Beta-galactosidase-1-like protein 2; Galactosidase beta 1 like 2	0.638
KIF18B	ECT2L	ENSP00000465992	ENSP00000442307	Kinesin-like protein KIF18B; In complex with KIF2C, constitutes the major microtubule plus-end depolymerizing activity in mitotic cells. Its major role may be to transport KIF2C and/or MAPRE1 along microtubules; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family	Epithelial cell-transforming sequence 2 oncogene-like; May act as a guanine nucleotide exchange factor (GEF); F-boxes other	0.533
KIF18B	GLB1L2	ENSP00000465992	ENSP00000444628	Kinesin-like protein KIF18B; In complex with KIF2C, constitutes the major microtubule plus-end depolymerizing activity in mitotic cells. Its major role may be to transport KIF2C and/or MAPRE1 along microtubules; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family	Beta-galactosidase-1-like protein 2; Galactosidase beta 1 like 2	0.656
KIF18B	KIF19	ENSP00000465992	ENSP00000374566	Kinesin-like protein KIF18B; In complex with KIF2C, constitutes the major microtubule plus-end depolymerizing activity in mitotic cells. Its major role may be to transport KIF2C and/or MAPRE1 along microtubules; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family	Kinesin-like protein KIF19; Plus end-directed microtubule-dependent motor protein that regulates the length of motile cilia by mediating depolymerization of microtubules at ciliary tips; Kinesins	0.915

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