node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KRT14 | KRT15 | ENSP00000167586 | ENSP00000254043 | Keratin, type I cytoskeletal 14; The nonhelical tail domain is involved in promoting KRT5-KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro | Keratin, type I cytoskeletal 15; Keratins, type I | 0.934 |
KRT14 | KRT16 | ENSP00000167586 | ENSP00000301653 | Keratin, type I cytoskeletal 14; The nonhelical tail domain is involved in promoting KRT5-KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro | Keratin, type I cytoskeletal 16; Epidermis-specific type I keratin that plays a key role in skin. Acts as a regulator of innate immunity in response to skin barrier breach- required for some inflammatory checkpoint for the skin barrier maintenance | 0.967 |
KRT14 | KRT25 | ENSP00000167586 | ENSP00000310573 | Keratin, type I cytoskeletal 14; The nonhelical tail domain is involved in promoting KRT5-KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro | Keratin, type I cytoskeletal 25; Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs) (By similarity). Plays a role in the cytoskeleton organization | 0.901 |
KRT14 | KRT28 | ENSP00000167586 | ENSP00000305263 | Keratin, type I cytoskeletal 14; The nonhelical tail domain is involved in promoting KRT5-KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro | Keratin, type I cytoskeletal 28; Essential for the proper assembly of types I and II keratin protein complexes and the formation of keratin intermediate filaments in the inner root sheath (irs) | 0.903 |
KRT14 | KRT32 | ENSP00000167586 | ENSP00000225899 | Keratin, type I cytoskeletal 14; The nonhelical tail domain is involved in promoting KRT5-KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro | Keratin, type I cuticular Ha2; Keratins, type I; Belongs to the intermediate filament family | 0.904 |
KRT14 | KRT34 | ENSP00000167586 | ENSP00000377570 | Keratin, type I cytoskeletal 14; The nonhelical tail domain is involved in promoting KRT5-KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro | Keratin, type I cuticular Ha4; Keratins, type I | 0.904 |
KRT14 | KRT35 | ENSP00000167586 | ENSP00000377558 | Keratin, type I cytoskeletal 14; The nonhelical tail domain is involved in promoting KRT5-KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro | Keratin, type I cuticular Ha5; Keratins, type I | 0.900 |
KRT14 | KRT36 | ENSP00000167586 | ENSP00000329165 | Keratin, type I cytoskeletal 14; The nonhelical tail domain is involved in promoting KRT5-KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro | Keratin, type I cuticular Ha6; Keratins, type I | 0.900 |
KRT14 | KRT81 | ENSP00000167586 | ENSP00000369349 | Keratin, type I cytoskeletal 14; The nonhelical tail domain is involved in promoting KRT5-KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro | Keratin, type II cuticular Hb1; Keratins, type II | 0.931 |
KRT14 | KRT86 | ENSP00000167586 | ENSP00000444533 | Keratin, type I cytoskeletal 14; The nonhelical tail domain is involved in promoting KRT5-KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro | Keratin, type II cuticular Hb6; Keratins, type II | 0.929 |
KRT15 | KRT14 | ENSP00000254043 | ENSP00000167586 | Keratin, type I cytoskeletal 15; Keratins, type I | Keratin, type I cytoskeletal 14; The nonhelical tail domain is involved in promoting KRT5-KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro | 0.934 |
KRT15 | KRT16 | ENSP00000254043 | ENSP00000301653 | Keratin, type I cytoskeletal 15; Keratins, type I | Keratin, type I cytoskeletal 16; Epidermis-specific type I keratin that plays a key role in skin. Acts as a regulator of innate immunity in response to skin barrier breach- required for some inflammatory checkpoint for the skin barrier maintenance | 0.916 |
KRT15 | KRT25 | ENSP00000254043 | ENSP00000310573 | Keratin, type I cytoskeletal 15; Keratins, type I | Keratin, type I cytoskeletal 25; Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs) (By similarity). Plays a role in the cytoskeleton organization | 0.902 |
KRT15 | KRT28 | ENSP00000254043 | ENSP00000305263 | Keratin, type I cytoskeletal 15; Keratins, type I | Keratin, type I cytoskeletal 28; Essential for the proper assembly of types I and II keratin protein complexes and the formation of keratin intermediate filaments in the inner root sheath (irs) | 0.902 |
KRT15 | KRT32 | ENSP00000254043 | ENSP00000225899 | Keratin, type I cytoskeletal 15; Keratins, type I | Keratin, type I cuticular Ha2; Keratins, type I; Belongs to the intermediate filament family | 0.907 |
KRT15 | KRT34 | ENSP00000254043 | ENSP00000377570 | Keratin, type I cytoskeletal 15; Keratins, type I | Keratin, type I cuticular Ha4; Keratins, type I | 0.904 |
KRT15 | KRT35 | ENSP00000254043 | ENSP00000377558 | Keratin, type I cytoskeletal 15; Keratins, type I | Keratin, type I cuticular Ha5; Keratins, type I | 0.902 |
KRT15 | KRT36 | ENSP00000254043 | ENSP00000329165 | Keratin, type I cytoskeletal 15; Keratins, type I | Keratin, type I cuticular Ha6; Keratins, type I | 0.903 |
KRT15 | KRT81 | ENSP00000254043 | ENSP00000369349 | Keratin, type I cytoskeletal 15; Keratins, type I | Keratin, type II cuticular Hb1; Keratins, type II | 0.930 |
KRT15 | KRT86 | ENSP00000254043 | ENSP00000444533 | Keratin, type I cytoskeletal 15; Keratins, type I | Keratin, type II cuticular Hb6; Keratins, type II | 0.927 |