node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ATXN10 | BEAN1 | ENSP00000252934 | ENSP00000442793 | Ataxin-10; Necessary for the survival of cerebellar neurons. Induces neuritogenesis by activating the Ras-MAP kinase pathway. May play a role in the maintenance of a critical intracellular glycosylation level and homeostasis; Armadillo-like helical domain containing | Protein BEAN1; Brain expressed associated with NEDD4 1 | 0.584 |
ATXN10 | NOP56 | ENSP00000252934 | ENSP00000370589 | Ataxin-10; Necessary for the survival of cerebellar neurons. Induces neuritogenesis by activating the Ras-MAP kinase pathway. May play a role in the maintenance of a critical intracellular glycosylation level and homeostasis; Armadillo-like helical domain containing | Nucleolar protein 56; Involved in the early to middle stages of 60S ribosomal subunit biogenesis. Core component of box C/D small nucleolar ribonucleoprotein (snoRNP) particles. Required for the biogenesis of box C/D snoRNAs such U3, U8 and U14 snoRNAs; Belongs to the NOP5/NOP56 family | 0.665 |
ATXN10 | PDYN | ENSP00000252934 | ENSP00000440185 | Ataxin-10; Necessary for the survival of cerebellar neurons. Induces neuritogenesis by activating the Ras-MAP kinase pathway. May play a role in the maintenance of a critical intracellular glycosylation level and homeostasis; Armadillo-like helical domain containing | Proenkephalin-B; Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress (By similarity); Belongs to the opioid neuropeptide precursor family | 0.578 |
ATXN10 | PLEKHG4 | ENSP00000252934 | ENSP00000353646 | Ataxin-10; Necessary for the survival of cerebellar neurons. Induces neuritogenesis by activating the Ras-MAP kinase pathway. May play a role in the maintenance of a critical intracellular glycosylation level and homeostasis; Armadillo-like helical domain containing | Puratrophin-1; Possible role in intracellular signaling and cytoskeleton dynamics at the Golgi; Pleckstrin homology domain containing | 0.669 |
ATXN10 | SYT14 | ENSP00000252934 | ENSP00000355986 | Ataxin-10; Necessary for the survival of cerebellar neurons. Induces neuritogenesis by activating the Ras-MAP kinase pathway. May play a role in the maintenance of a critical intracellular glycosylation level and homeostasis; Armadillo-like helical domain containing | Synaptotagmin-14; May be involved in the trafficking and exocytosis of secretory vesicles in non-neuronal tissues. Is Ca(2+)-independent; Belongs to the synaptotagmin family | 0.483 |
ATXN10 | ZNF592 | ENSP00000252934 | ENSP00000452877 | Ataxin-10; Necessary for the survival of cerebellar neurons. Induces neuritogenesis by activating the Ras-MAP kinase pathway. May play a role in the maintenance of a critical intracellular glycosylation level and homeostasis; Armadillo-like helical domain containing | Zinc finger protein 592; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.512 |
BEAN1 | ATXN10 | ENSP00000442793 | ENSP00000252934 | Protein BEAN1; Brain expressed associated with NEDD4 1 | Ataxin-10; Necessary for the survival of cerebellar neurons. Induces neuritogenesis by activating the Ras-MAP kinase pathway. May play a role in the maintenance of a critical intracellular glycosylation level and homeostasis; Armadillo-like helical domain containing | 0.584 |
BEAN1 | CALB1 | ENSP00000442793 | ENSP00000265431 | Protein BEAN1; Brain expressed associated with NEDD4 1 | Calbindin; Buffers cytosolic calcium. May stimulate a membrane Ca(2+)-ATPase and a 3’,5’-cyclic nucleotide phosphodiesterase; EF-hand domain containing | 0.642 |
BEAN1 | CHRNA4 | ENSP00000442793 | ENSP00000359285 | Protein BEAN1; Brain expressed associated with NEDD4 1 | Neuronal acetylcholine receptor subunit alpha-4; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane permeable to sodium ions; Cholinergic receptors nicotinic subunits | 0.611 |
BEAN1 | DNAJC21 | ENSP00000442793 | ENSP00000371451 | Protein BEAN1; Brain expressed associated with NEDD4 1 | DnaJ homolog subfamily C member 21; May act as a co-chaperone for HSP70. May play a role in ribosomal RNA (rRNA) biogenesis, possibly in the maturation of the 60S subunit. Binds the precursor 45S rRNA; DNAJ heat shock proteins | 0.545 |
BEAN1 | NOP56 | ENSP00000442793 | ENSP00000370589 | Protein BEAN1; Brain expressed associated with NEDD4 1 | Nucleolar protein 56; Involved in the early to middle stages of 60S ribosomal subunit biogenesis. Core component of box C/D small nucleolar ribonucleoprotein (snoRNP) particles. Required for the biogenesis of box C/D snoRNAs such U3, U8 and U14 snoRNAs; Belongs to the NOP5/NOP56 family | 0.560 |
BEAN1 | PDYN | ENSP00000442793 | ENSP00000440185 | Protein BEAN1; Brain expressed associated with NEDD4 1 | Proenkephalin-B; Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress (By similarity); Belongs to the opioid neuropeptide precursor family | 0.545 |
BEAN1 | PLEKHG4 | ENSP00000442793 | ENSP00000353646 | Protein BEAN1; Brain expressed associated with NEDD4 1 | Puratrophin-1; Possible role in intracellular signaling and cytoskeleton dynamics at the Golgi; Pleckstrin homology domain containing | 0.711 |
BEAN1 | SRSF9 | ENSP00000442793 | ENSP00000229390 | Protein BEAN1; Brain expressed associated with NEDD4 1 | Serine/arginine-rich splicing factor 9; Plays a role in constitutive splicing and can modulate the selection of alternative splice sites. Represses the splicing of MAPT/Tau exon 10; Belongs to the splicing factor SR family | 0.710 |
BEAN1 | SYT14 | ENSP00000442793 | ENSP00000355986 | Protein BEAN1; Brain expressed associated with NEDD4 1 | Synaptotagmin-14; May be involved in the trafficking and exocytosis of secretory vesicles in non-neuronal tissues. Is Ca(2+)-independent; Belongs to the synaptotagmin family | 0.566 |
BEAN1 | ZNF592 | ENSP00000442793 | ENSP00000452877 | Protein BEAN1; Brain expressed associated with NEDD4 1 | Zinc finger protein 592; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.537 |
CALB1 | BEAN1 | ENSP00000265431 | ENSP00000442793 | Calbindin; Buffers cytosolic calcium. May stimulate a membrane Ca(2+)-ATPase and a 3’,5’-cyclic nucleotide phosphodiesterase; EF-hand domain containing | Protein BEAN1; Brain expressed associated with NEDD4 1 | 0.642 |
CALB1 | PDYN | ENSP00000265431 | ENSP00000440185 | Calbindin; Buffers cytosolic calcium. May stimulate a membrane Ca(2+)-ATPase and a 3’,5’-cyclic nucleotide phosphodiesterase; EF-hand domain containing | Proenkephalin-B; Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress (By similarity); Belongs to the opioid neuropeptide precursor family | 0.530 |
CALB1 | PLEKHG4 | ENSP00000265431 | ENSP00000353646 | Calbindin; Buffers cytosolic calcium. May stimulate a membrane Ca(2+)-ATPase and a 3’,5’-cyclic nucleotide phosphodiesterase; EF-hand domain containing | Puratrophin-1; Possible role in intracellular signaling and cytoskeleton dynamics at the Golgi; Pleckstrin homology domain containing | 0.468 |
CHRNA4 | BEAN1 | ENSP00000359285 | ENSP00000442793 | Neuronal acetylcholine receptor subunit alpha-4; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane permeable to sodium ions; Cholinergic receptors nicotinic subunits | Protein BEAN1; Brain expressed associated with NEDD4 1 | 0.611 |