node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CRIP1 | LMO3 | ENSP00000332449 | ENSP00000442786 | Cysteine-rich protein 1; Seems to have a role in zinc absorption and may function as an intracellular zinc transport protein; LIM domain containing | LIM domain only protein 3; LIM domain containing | 0.759 |
CSRP1 | LMO3 | ENSP00000356275 | ENSP00000442786 | Cysteine and glycine-rich protein 1; Could play a role in neuronal development; LIM domain containing | LIM domain only protein 3; LIM domain containing | 0.764 |
CSRP2 | LMO3 | ENSP00000310901 | ENSP00000442786 | Cysteine and glycine-rich protein 2; Drastically down-regulated in response to PDGF-BB or cell injury, that promote smooth muscle cell proliferation and dedifferentiation. Seems to play a role in the development of the embryonic vascular system; LIM domain containing | LIM domain only protein 3; LIM domain containing | 0.566 |
LDB1 | LDB2 | ENSP00000392466 | ENSP00000306772 | LIM domain-binding protein 1; Binds to the LIM domain of a wide variety of LIM domain- containing transcription factors. May regulate the transcriptional activity of LIM-containing proteins by determining specific partner interactions. Plays a role in the development of interneurons and motor neurons in cooperation with LHX3 and ISL1. Acts synergistically with LHX1/LIM1 in axis formation and activation of gene expression. Acts with LMO2 in the regulation of red blood cell development, maintaining erythroid precursors in an immature state (By similarity) | LIM domain-binding protein 2; Binds to the LIM domain of a wide variety of LIM domain- containing transcription factors; Belongs to the LDB family | 0.735 |
LDB1 | LMO3 | ENSP00000392466 | ENSP00000442786 | LIM domain-binding protein 1; Binds to the LIM domain of a wide variety of LIM domain- containing transcription factors. May regulate the transcriptional activity of LIM-containing proteins by determining specific partner interactions. Plays a role in the development of interneurons and motor neurons in cooperation with LHX3 and ISL1. Acts synergistically with LHX1/LIM1 in axis formation and activation of gene expression. Acts with LMO2 in the regulation of red blood cell development, maintaining erythroid precursors in an immature state (By similarity) | LIM domain only protein 3; LIM domain containing | 0.887 |
LDB1 | NHLH2 | ENSP00000392466 | ENSP00000358519 | LIM domain-binding protein 1; Binds to the LIM domain of a wide variety of LIM domain- containing transcription factors. May regulate the transcriptional activity of LIM-containing proteins by determining specific partner interactions. Plays a role in the development of interneurons and motor neurons in cooperation with LHX3 and ISL1. Acts synergistically with LHX1/LIM1 in axis formation and activation of gene expression. Acts with LMO2 in the regulation of red blood cell development, maintaining erythroid precursors in an immature state (By similarity) | Helix-loop-helix protein 2; May serve as DNA-binding protein and may be involved in the control of cell-type determination, possibly within the developing nervous system; Basic helix-loop-helix proteins | 0.805 |
LDB2 | LDB1 | ENSP00000306772 | ENSP00000392466 | LIM domain-binding protein 2; Binds to the LIM domain of a wide variety of LIM domain- containing transcription factors; Belongs to the LDB family | LIM domain-binding protein 1; Binds to the LIM domain of a wide variety of LIM domain- containing transcription factors. May regulate the transcriptional activity of LIM-containing proteins by determining specific partner interactions. Plays a role in the development of interneurons and motor neurons in cooperation with LHX3 and ISL1. Acts synergistically with LHX1/LIM1 in axis formation and activation of gene expression. Acts with LMO2 in the regulation of red blood cell development, maintaining erythroid precursors in an immature state (By similarity) | 0.735 |
LDB2 | LMO3 | ENSP00000306772 | ENSP00000442786 | LIM domain-binding protein 2; Binds to the LIM domain of a wide variety of LIM domain- containing transcription factors; Belongs to the LDB family | LIM domain only protein 3; LIM domain containing | 0.890 |
LDB2 | NHLH2 | ENSP00000306772 | ENSP00000358519 | LIM domain-binding protein 2; Binds to the LIM domain of a wide variety of LIM domain- containing transcription factors; Belongs to the LDB family | Helix-loop-helix protein 2; May serve as DNA-binding protein and may be involved in the control of cell-type determination, possibly within the developing nervous system; Basic helix-loop-helix proteins | 0.810 |
LIX1 | LMO3 | ENSP00000274382 | ENSP00000442786 | Protein limb expression 1 homolog; Limb and CNS expressed 1; Belongs to the LIX1 family | LIM domain only protein 3; LIM domain containing | 0.543 |
LMO3 | CRIP1 | ENSP00000442786 | ENSP00000332449 | LIM domain only protein 3; LIM domain containing | Cysteine-rich protein 1; Seems to have a role in zinc absorption and may function as an intracellular zinc transport protein; LIM domain containing | 0.759 |
LMO3 | CSRP1 | ENSP00000442786 | ENSP00000356275 | LIM domain only protein 3; LIM domain containing | Cysteine and glycine-rich protein 1; Could play a role in neuronal development; LIM domain containing | 0.764 |
LMO3 | CSRP2 | ENSP00000442786 | ENSP00000310901 | LIM domain only protein 3; LIM domain containing | Cysteine and glycine-rich protein 2; Drastically down-regulated in response to PDGF-BB or cell injury, that promote smooth muscle cell proliferation and dedifferentiation. Seems to play a role in the development of the embryonic vascular system; LIM domain containing | 0.566 |
LMO3 | LDB1 | ENSP00000442786 | ENSP00000392466 | LIM domain only protein 3; LIM domain containing | LIM domain-binding protein 1; Binds to the LIM domain of a wide variety of LIM domain- containing transcription factors. May regulate the transcriptional activity of LIM-containing proteins by determining specific partner interactions. Plays a role in the development of interneurons and motor neurons in cooperation with LHX3 and ISL1. Acts synergistically with LHX1/LIM1 in axis formation and activation of gene expression. Acts with LMO2 in the regulation of red blood cell development, maintaining erythroid precursors in an immature state (By similarity) | 0.887 |
LMO3 | LDB2 | ENSP00000442786 | ENSP00000306772 | LIM domain only protein 3; LIM domain containing | LIM domain-binding protein 2; Binds to the LIM domain of a wide variety of LIM domain- containing transcription factors; Belongs to the LDB family | 0.890 |
LMO3 | LIX1 | ENSP00000442786 | ENSP00000274382 | LIM domain only protein 3; LIM domain containing | Protein limb expression 1 homolog; Limb and CNS expressed 1; Belongs to the LIX1 family | 0.543 |
LMO3 | NHLH2 | ENSP00000442786 | ENSP00000358519 | LIM domain only protein 3; LIM domain containing | Helix-loop-helix protein 2; May serve as DNA-binding protein and may be involved in the control of cell-type determination, possibly within the developing nervous system; Basic helix-loop-helix proteins | 0.597 |
LMO3 | NR4A2 | ENSP00000442786 | ENSP00000344479 | LIM domain only protein 3; LIM domain containing | Nuclear receptor subfamily 4 group A member 2; Transcriptional regulator which is important for the differentiation and maintenance of meso-diencephalic dopaminergic (mdDA) neurons during development. It is crucial for expression of a set of genes such as SLC6A3, SLC18A2, TH and DRD2 which are essential for development of mdDA neurons (By similarity); Belongs to the nuclear hormone receptor family. NR4 subfamily | 0.640 |
LMO3 | PAX6 | ENSP00000442786 | ENSP00000404100 | LIM domain only protein 3; LIM domain containing | Paired box protein Pax-6; Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells (By similarity). Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (By similarity). Isoform 5a appears to function as a molecular switch that specifies target genes; Belongs to the paired homeobox family | 0.581 |
LMO3 | TBR1 | ENSP00000442786 | ENSP00000374205 | LIM domain only protein 3; LIM domain containing | T-box brain protein 1; Probable transcriptional regulator involved in developmental processes. Required for normal brain development; T-boxes | 0.623 |