• Version:
  • 11.0 [archived version]
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SPRYD3 SPRYD3 PFDN5 PFDN5 MFSD5 MFSD5 MFSD11 MFSD11 MFSD10 MFSD10 KIAA1919 KIAA1919 MFSD9 MFSD9 MFSD8 MFSD8 SV2C SV2C SVOPL SVOPL SVOP SVOP
"MFSD5" - Molybdate-anion transporter in Homo sapiens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
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MFSD5Molybdate-anion transporter; Mediates high-affinity intracellular uptake of the rare oligo-element molybdenum; Belongs to the major facilitator superfamily (557 aa)    
Predicted Functional Partners:
MFSD11
UNC93-like protein MFSD11; Major facilitator superfamily domain containing 11; Belongs to the unc-93 family (449 aa)
     
   
  0.873
SVOP
Synaptic vesicle 2-related protein; SV2 related protein (548 aa)
           
  0.802
SVOPL
Putative transporter SVOPL; SVOP like; Belongs to the major facilitator superfamily (492 aa)
           
  0.801
MFSD10
Major facilitator superfamily domain-containing protein 10; Confers cellular resistance to apoptosis induced by the non-steroidal anti-inflammatory drugs indomethacin and diclofenac. May act as an efflux pump (455 aa)
     
   
  0.801
SPRYD3
SPRY domain containing 3 (442 aa)
           
  0.782
KIAA1919
Sodium-dependent glucose transporter 1; May function as a sodium-dependent glucose transporter. Potential channels for urea in the inner medulla of kidney (518 aa)
     
   
  0.762
SV2C
Synaptic vesicle glycoprotein 2C; Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles (By similarity) (727 aa)
           
  0.755
PFDN5
Prefoldin subunit 5; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins. Represses the transcriptional activity of MYC; Belongs to the prefoldin subunit alpha family (154 aa)
           
  0.745
MFSD9
Major facilitator superfamily domain containing 9 (474 aa)
           
  0.738
MFSD8
Major facilitator superfamily domain-containing protein 8; May be a carrier that transport small solutes by using chemiosmotic ion gradients; Belongs to the major facilitator superfamily (518 aa)
           
  0.692
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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