STOML1 protein (human) - STRING database

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STOML1

Stomatin-like protein 1; May play a role in cholesterol transfer to late endosomes. May play a role in modulating membrane acid-sensing ion channels. Can specifically inhibit proton-gated current of ASIC1 isoform 1. Can increase inactivation speed of ASIC3. May be involved in regulation of proton sensing in dorsal root ganglions (By similarity). May play a role in protecting FBXW7 isoform 3 from degradation; Belongs to the band 7/mec-2 family (398 aa)

Predicted Functional Partners:

SDR39U1

0.762

RNF17

0.731

WDR73

0.730

SCP2D1

0.723

UNC119

0.715

RBM34

0.714

LOXL1

0.703

STXBP6

0.692

NYNRIN

0.684

PEX5L

0.668

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOXL1	NYNRIN	ENSP00000261921	ENSP00000371994	Lysyl oxidase homolog 1; Active on elastin and collagen substrates	Protein NYNRIN; NYN domain and retroviral integrase containing	0.437
LOXL1	RNF17	ENSP00000261921	ENSP00000255324	Lysyl oxidase homolog 1; Active on elastin and collagen substrates	RING finger protein 17; Seems to be involved in regulation of transcriptional activity of MYC. In vitro, inhibits DNA-binding activity of Mad- MAX heterodimers. Can recruit Mad transcriptional repressors (MXD1, MXD3, MXD4 and MXI1) to the cytoplasm. May be involved in spermiogenesis (By similarity); Ring finger proteins	0.448
LOXL1	SDR39U1	ENSP00000261921	ENSP00000382327	Lysyl oxidase homolog 1; Active on elastin and collagen substrates	Epimerase family protein SDR39U1; Putative NADP-dependent oxidoreductase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily	0.659
LOXL1	STOML1	ENSP00000261921	ENSP00000442478	Lysyl oxidase homolog 1; Active on elastin and collagen substrates	Stomatin-like protein 1; May play a role in cholesterol transfer to late endosomes. May play a role in modulating membrane acid-sensing ion channels. Can specifically inhibit proton-gated current of ASIC1 isoform 1. Can increase inactivation speed of ASIC3. May be involved in regulation of proton sensing in dorsal root ganglions (By similarity). May play a role in protecting FBXW7 isoform 3 from degradation; Belongs to the band 7/mec-2 family	0.703
LOXL1	STXBP6	ENSP00000261921	ENSP00000324302	Lysyl oxidase homolog 1; Active on elastin and collagen substrates	Syntaxin-binding protein 6; Forms non-fusogenic complexes with SNAP25 and STX1A and may thereby modulate the formation of functional SNARE complexes and exocytosis	0.560
NYNRIN	LOXL1	ENSP00000371994	ENSP00000261921	Protein NYNRIN; NYN domain and retroviral integrase containing	Lysyl oxidase homolog 1; Active on elastin and collagen substrates	0.437
NYNRIN	RNF17	ENSP00000371994	ENSP00000255324	Protein NYNRIN; NYN domain and retroviral integrase containing	RING finger protein 17; Seems to be involved in regulation of transcriptional activity of MYC. In vitro, inhibits DNA-binding activity of Mad- MAX heterodimers. Can recruit Mad transcriptional repressors (MXD1, MXD3, MXD4 and MXI1) to the cytoplasm. May be involved in spermiogenesis (By similarity); Ring finger proteins	0.512
NYNRIN	SDR39U1	ENSP00000371994	ENSP00000382327	Protein NYNRIN; NYN domain and retroviral integrase containing	Epimerase family protein SDR39U1; Putative NADP-dependent oxidoreductase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily	0.746
NYNRIN	STOML1	ENSP00000371994	ENSP00000442478	Protein NYNRIN; NYN domain and retroviral integrase containing	Stomatin-like protein 1; May play a role in cholesterol transfer to late endosomes. May play a role in modulating membrane acid-sensing ion channels. Can specifically inhibit proton-gated current of ASIC1 isoform 1. Can increase inactivation speed of ASIC3. May be involved in regulation of proton sensing in dorsal root ganglions (By similarity). May play a role in protecting FBXW7 isoform 3 from degradation; Belongs to the band 7/mec-2 family	0.684
NYNRIN	STXBP6	ENSP00000371994	ENSP00000324302	Protein NYNRIN; NYN domain and retroviral integrase containing	Syntaxin-binding protein 6; Forms non-fusogenic complexes with SNAP25 and STX1A and may thereby modulate the formation of functional SNARE complexes and exocytosis	0.671
PEX5L	SCP2D1	ENSP00000419975	ENSP00000366645	PEX5-related protein; Accessory subunit of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels, regulating their cell-surface expression and cyclic nucleotide dependence; Belongs to the peroxisomal targeting signal receptor family	SCP2 sterol-binding domain-containing protein 1; SCP2 sterol binding domain containing 1	0.668
PEX5L	STOML1	ENSP00000419975	ENSP00000442478	PEX5-related protein; Accessory subunit of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels, regulating their cell-surface expression and cyclic nucleotide dependence; Belongs to the peroxisomal targeting signal receptor family	Stomatin-like protein 1; May play a role in cholesterol transfer to late endosomes. May play a role in modulating membrane acid-sensing ion channels. Can specifically inhibit proton-gated current of ASIC1 isoform 1. Can increase inactivation speed of ASIC3. May be involved in regulation of proton sensing in dorsal root ganglions (By similarity). May play a role in protecting FBXW7 isoform 3 from degradation; Belongs to the band 7/mec-2 family	0.668
RBM34	STOML1	ENSP00000386226	ENSP00000442478	RNA-binding protein 34; RNA binding motif containing; Belongs to the RRM RBM34 family	Stomatin-like protein 1; May play a role in cholesterol transfer to late endosomes. May play a role in modulating membrane acid-sensing ion channels. Can specifically inhibit proton-gated current of ASIC1 isoform 1. Can increase inactivation speed of ASIC3. May be involved in regulation of proton sensing in dorsal root ganglions (By similarity). May play a role in protecting FBXW7 isoform 3 from degradation; Belongs to the band 7/mec-2 family	0.714
RBM34	WDR73	ENSP00000386226	ENSP00000387982	RNA-binding protein 34; RNA binding motif containing; Belongs to the RRM RBM34 family	WD repeat-containing protein 73; May play a role in the regulation of microtubule organization and dynamics; WD repeat domain containing	0.739
RNF17	LOXL1	ENSP00000255324	ENSP00000261921	RING finger protein 17; Seems to be involved in regulation of transcriptional activity of MYC. In vitro, inhibits DNA-binding activity of Mad- MAX heterodimers. Can recruit Mad transcriptional repressors (MXD1, MXD3, MXD4 and MXI1) to the cytoplasm. May be involved in spermiogenesis (By similarity); Ring finger proteins	Lysyl oxidase homolog 1; Active on elastin and collagen substrates	0.448
RNF17	NYNRIN	ENSP00000255324	ENSP00000371994	RING finger protein 17; Seems to be involved in regulation of transcriptional activity of MYC. In vitro, inhibits DNA-binding activity of Mad- MAX heterodimers. Can recruit Mad transcriptional repressors (MXD1, MXD3, MXD4 and MXI1) to the cytoplasm. May be involved in spermiogenesis (By similarity); Ring finger proteins	Protein NYNRIN; NYN domain and retroviral integrase containing	0.512
RNF17	SDR39U1	ENSP00000255324	ENSP00000382327	RING finger protein 17; Seems to be involved in regulation of transcriptional activity of MYC. In vitro, inhibits DNA-binding activity of Mad- MAX heterodimers. Can recruit Mad transcriptional repressors (MXD1, MXD3, MXD4 and MXI1) to the cytoplasm. May be involved in spermiogenesis (By similarity); Ring finger proteins	Epimerase family protein SDR39U1; Putative NADP-dependent oxidoreductase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily	0.667
RNF17	STOML1	ENSP00000255324	ENSP00000442478	RING finger protein 17; Seems to be involved in regulation of transcriptional activity of MYC. In vitro, inhibits DNA-binding activity of Mad- MAX heterodimers. Can recruit Mad transcriptional repressors (MXD1, MXD3, MXD4 and MXI1) to the cytoplasm. May be involved in spermiogenesis (By similarity); Ring finger proteins	Stomatin-like protein 1; May play a role in cholesterol transfer to late endosomes. May play a role in modulating membrane acid-sensing ion channels. Can specifically inhibit proton-gated current of ASIC1 isoform 1. Can increase inactivation speed of ASIC3. May be involved in regulation of proton sensing in dorsal root ganglions (By similarity). May play a role in protecting FBXW7 isoform 3 from degradation; Belongs to the band 7/mec-2 family	0.731
RNF17	STXBP6	ENSP00000255324	ENSP00000324302	RING finger protein 17; Seems to be involved in regulation of transcriptional activity of MYC. In vitro, inhibits DNA-binding activity of Mad- MAX heterodimers. Can recruit Mad transcriptional repressors (MXD1, MXD3, MXD4 and MXI1) to the cytoplasm. May be involved in spermiogenesis (By similarity); Ring finger proteins	Syntaxin-binding protein 6; Forms non-fusogenic complexes with SNAP25 and STX1A and may thereby modulate the formation of functional SNARE complexes and exocytosis	0.585
SCP2D1	PEX5L	ENSP00000366645	ENSP00000419975	SCP2 sterol-binding domain-containing protein 1; SCP2 sterol binding domain containing 1	PEX5-related protein; Accessory subunit of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels, regulating their cell-surface expression and cyclic nucleotide dependence; Belongs to the peroxisomal targeting signal receptor family	0.668

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