FNDC3A protein (human) - STRING database

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

FNDC3A

Fibronectin type-III domain-containing protein 3A; Mediates spermatid-Sertoli adhesion during spermatogenesis; Belongs to the FNDC3 family (1198 aa)

Predicted Functional Partners:

CNNM1

0.757

HPSE2

0.756

CRABP2

0.716

SOX15

0.712

CAB39L

0.712

MLNR

0.710

RCBTB2

0.655

TMEM209

0.651

PHF11

0.647

RPL23

0.640

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but resolution at 400 dpi

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as simple tabular text output:

download

TSV: tab separated values - can be opened in Excel

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CAB39L	FNDC3A	ENSP00000479669	ENSP00000441831	Calcium-binding protein 39-like; Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1 (By similarity)	Fibronectin type-III domain-containing protein 3A; Mediates spermatid-Sertoli adhesion during spermatogenesis; Belongs to the FNDC3 family	0.712
CAB39L	MLNR	ENSP00000479669	ENSP00000218721	Calcium-binding protein 39-like; Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1 (By similarity)	Motilin receptor; Receptor for motilin; Belongs to the G-protein coupled receptor 1 family	0.631
CAB39L	PHF11	ENSP00000479669	ENSP00000367570	Calcium-binding protein 39-like; Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1 (By similarity)	PHD finger protein 11; Positive regulator of Th1-type cytokine gene expression; PHD finger proteins	0.687
CAB39L	RCBTB2	ENSP00000479669	ENSP00000389910	Calcium-binding protein 39-like; Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1 (By similarity)	RCC1 and BTB domain containing protein 2	0.640
CNNM1	CRABP2	ENSP00000349147	ENSP00000482841	Metal transporter CNNM1; Probable metal transporter; Belongs to the ACDP family	Cellular retinoic acid-binding protein 2; Transports retinoic acid to the nucleus. Regulates the access of retinoic acid to the nuclear retinoic acid receptors; Fatty acid binding protein family	0.889
CNNM1	FNDC3A	ENSP00000349147	ENSP00000441831	Metal transporter CNNM1; Probable metal transporter; Belongs to the ACDP family	Fibronectin type-III domain-containing protein 3A; Mediates spermatid-Sertoli adhesion during spermatogenesis; Belongs to the FNDC3 family	0.757
CNNM1	HPSE2	ENSP00000349147	ENSP00000359583	Metal transporter CNNM1; Probable metal transporter; Belongs to the ACDP family	Inactive heparanase-2; Binds heparin and heparan sulfate with high affinity, but lacks heparanase activity. Inhibits HPSE, possibly by competing for its substrates (in vitro)	0.929
CRABP2	CNNM1	ENSP00000482841	ENSP00000349147	Cellular retinoic acid-binding protein 2; Transports retinoic acid to the nucleus. Regulates the access of retinoic acid to the nuclear retinoic acid receptors; Fatty acid binding protein family	Metal transporter CNNM1; Probable metal transporter; Belongs to the ACDP family	0.889
CRABP2	FNDC3A	ENSP00000482841	ENSP00000441831	Cellular retinoic acid-binding protein 2; Transports retinoic acid to the nucleus. Regulates the access of retinoic acid to the nuclear retinoic acid receptors; Fatty acid binding protein family	Fibronectin type-III domain-containing protein 3A; Mediates spermatid-Sertoli adhesion during spermatogenesis; Belongs to the FNDC3 family	0.716
CRABP2	HPSE2	ENSP00000482841	ENSP00000359583	Cellular retinoic acid-binding protein 2; Transports retinoic acid to the nucleus. Regulates the access of retinoic acid to the nuclear retinoic acid receptors; Fatty acid binding protein family	Inactive heparanase-2; Binds heparin and heparan sulfate with high affinity, but lacks heparanase activity. Inhibits HPSE, possibly by competing for its substrates (in vitro)	0.844
FNDC3A	CAB39L	ENSP00000441831	ENSP00000479669	Fibronectin type-III domain-containing protein 3A; Mediates spermatid-Sertoli adhesion during spermatogenesis; Belongs to the FNDC3 family	Calcium-binding protein 39-like; Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1 (By similarity)	0.712
FNDC3A	CNNM1	ENSP00000441831	ENSP00000349147	Fibronectin type-III domain-containing protein 3A; Mediates spermatid-Sertoli adhesion during spermatogenesis; Belongs to the FNDC3 family	Metal transporter CNNM1; Probable metal transporter; Belongs to the ACDP family	0.757
FNDC3A	CRABP2	ENSP00000441831	ENSP00000482841	Fibronectin type-III domain-containing protein 3A; Mediates spermatid-Sertoli adhesion during spermatogenesis; Belongs to the FNDC3 family	Cellular retinoic acid-binding protein 2; Transports retinoic acid to the nucleus. Regulates the access of retinoic acid to the nuclear retinoic acid receptors; Fatty acid binding protein family	0.716
FNDC3A	HPSE2	ENSP00000441831	ENSP00000359583	Fibronectin type-III domain-containing protein 3A; Mediates spermatid-Sertoli adhesion during spermatogenesis; Belongs to the FNDC3 family	Inactive heparanase-2; Binds heparin and heparan sulfate with high affinity, but lacks heparanase activity. Inhibits HPSE, possibly by competing for its substrates (in vitro)	0.756
FNDC3A	MLNR	ENSP00000441831	ENSP00000218721	Fibronectin type-III domain-containing protein 3A; Mediates spermatid-Sertoli adhesion during spermatogenesis; Belongs to the FNDC3 family	Motilin receptor; Receptor for motilin; Belongs to the G-protein coupled receptor 1 family	0.710
FNDC3A	PHF11	ENSP00000441831	ENSP00000367570	Fibronectin type-III domain-containing protein 3A; Mediates spermatid-Sertoli adhesion during spermatogenesis; Belongs to the FNDC3 family	PHD finger protein 11; Positive regulator of Th1-type cytokine gene expression; PHD finger proteins	0.647
FNDC3A	RCBTB2	ENSP00000441831	ENSP00000389910	Fibronectin type-III domain-containing protein 3A; Mediates spermatid-Sertoli adhesion during spermatogenesis; Belongs to the FNDC3 family	RCC1 and BTB domain containing protein 2	0.655
FNDC3A	RPL23	ENSP00000441831	ENSP00000420311	Fibronectin type-III domain-containing protein 3A; Mediates spermatid-Sertoli adhesion during spermatogenesis; Belongs to the FNDC3 family	Ribosomal protein L23	0.640
FNDC3A	SOX15	ENSP00000441831	ENSP00000355354	Fibronectin type-III domain-containing protein 3A; Mediates spermatid-Sertoli adhesion during spermatogenesis; Belongs to the FNDC3 family	Protein SOX-15; Binds to the 5’-AACAAT-3’ sequence; SRY-boxes	0.712
FNDC3A	TMEM209	ENSP00000441831	ENSP00000380747	Fibronectin type-III domain-containing protein 3A; Mediates spermatid-Sertoli adhesion during spermatogenesis; Belongs to the FNDC3 family	Transmembrane protein 209	0.651

page 1 of 2

Network

Cooccurrence

Experiments

Coexpression

Textmining

Neighborhood

Databases

Fusion

© STRING Consortium 2020

Credits

Access

Info

About