• Version:
  • 11.0 [archived version]
STRINGSTRING
ZDBF2 ZDBF2 TSPYL2 TSPYL2 TMEM179 TMEM179 SHISA9 SHISA9 MRPL48 MRPL48 R3HDML R3HDML GDAP1L1 GDAP1L1 NETO1 NETO1 CDH18 CDH18 FBXL16 FBXL16 RUNDC3A RUNDC3A
"GDAP1L1" - Ganglioside-induced differentiation-associated protein 1-like 1 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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GDAP1L1Ganglioside-induced differentiation-associated protein 1-like 1; Ganglioside induced differentiation associated protein 1 like 1 (386 aa)    
Predicted Functional Partners:
MRPL48
Mitochondrial ribosomal protein L48 (212 aa)
           
  0.711
CDH18
Cadherin-18; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types (790 aa)
     
   
  0.664
ZDBF2
DBF4-type zinc finger-containing protein 2; Zinc finger DBF-type containing 2 (2354 aa)
           
  0.633
RUNDC3A
RUN domain-containing protein 3A; May act as an effector of RAP2A in neuronal cells; Belongs to the RUNDC3 family (446 aa)
     
   
  0.631
R3HDML
Peptidase inhibitor R3HDML; Putative serine protease inhibitor; CAP superfamily (253 aa)
           
  0.626
TSPYL2
Testis-specific Y-encoded-like protein 2; Part of the CASK/TBR1/TSPYL2 transcriptional complex which modulates gene expression in response to neuronal synaptic activity, probably by facilitating nucleosome assembly. May inhibit cell proliferation by inducing p53-dependent CDKN1A expression (693 aa)
           
  0.621
TMEM179
Transmembrane protein 179; Belongs to the TMEM179 family (233 aa)
     
   
  0.615
SHISA9
Protein shisa-9; Regulator of short-term neuronal synaptic plasticity in the dentate gyrus. Associates with AMPA receptors (ionotropic glutamate receptors) in synaptic spines and promotes AMPA receptor desensitization at excitatory synapses (By similarity); Belongs to the shisa family. SHISA9 subfamily (424 aa)
     
   
  0.606
NETO1
Neuropilin and tolloid-like protein 1; Involved in the development and/or maintenance of neuronal circuitry. Accessory subunit of the neuronal N-methyl-D- aspartate receptor (NMDAR) critical for maintaining the abundance of GRIN2A-containing NMDARs in the postsynaptic density. Regulates long-term NMDA receptor-dependent synaptic plasticity and cognition, at least in the context of spatial learning and memory (By similarity) (533 aa)
     
   
  0.602
FBXL16
F-box/LRR-repeat protein 16; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex; F-box and leucine rich repeat proteins (479 aa)
     
   
  0.581
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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