node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CRYZL1 | DONSON | ENSP00000370966 | ENSP00000307143 | Quinone oxidoreductase-like protein 1; Crystallin zeta like 1; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily | Protein downstream neighbor of Son; Replisome component that maintains genome stability by protecting stalled or damaged replication forks. After the induction of replication stress, required for the stabilization of stalled replication forks, the efficient activation of the intra- S-phase and G/2M cell-cycle checkpoints and the maintenance of genome stability | 0.708 |
CRYZL1 | MRPS6 | ENSP00000370966 | ENSP00000382250 | Quinone oxidoreductase-like protein 1; Crystallin zeta like 1; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily | Mitochondrial ribosomal protein S6 | 0.691 |
CRYZL1 | PAXBP1 | ENSP00000370966 | ENSP00000328992 | Quinone oxidoreductase-like protein 1; Crystallin zeta like 1; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily | PAX3- and PAX7-binding protein 1; Adapter protein linking the transcription factors PAX3 and PAX7 to the histone methylation machinery and involved in myogenesis. Associates with a histone methyltransferase complex that specifically mediates dimethylation and trimethylation of ’Lys-4’ of histone H3. Mediates the recruitment of that complex to the transcription factors PAX3 and PAX7 on chromatin to regulate the expression of genes involved in muscle progenitor cells proliferation including ID3 and CDC20 (By similarity) | 0.400 |
CRYZL1 | TMEM50B | ENSP00000370966 | ENSP00000439768 | Quinone oxidoreductase-like protein 1; Crystallin zeta like 1; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily | Transmembrane protein 50B | 0.697 |
DDI2 | TMEM50B | ENSP00000417748 | ENSP00000439768 | DNA damage inducible 1 homolog 2; Belongs to the DDI1 family | Transmembrane protein 50B | 0.545 |
DONSON | CRYZL1 | ENSP00000307143 | ENSP00000370966 | Protein downstream neighbor of Son; Replisome component that maintains genome stability by protecting stalled or damaged replication forks. After the induction of replication stress, required for the stabilization of stalled replication forks, the efficient activation of the intra- S-phase and G/2M cell-cycle checkpoints and the maintenance of genome stability | Quinone oxidoreductase-like protein 1; Crystallin zeta like 1; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily | 0.708 |
DONSON | DOPEY2 | ENSP00000307143 | ENSP00000382104 | Protein downstream neighbor of Son; Replisome component that maintains genome stability by protecting stalled or damaged replication forks. After the induction of replication stress, required for the stabilization of stalled replication forks, the efficient activation of the intra- S-phase and G/2M cell-cycle checkpoints and the maintenance of genome stability | Protein dopey-2; May be involved in protein traffic between late Golgi and early endosomes; Belongs to the dopey family | 0.479 |
DONSON | DSCR3 | ENSP00000307143 | ENSP00000311399 | Protein downstream neighbor of Son; Replisome component that maintains genome stability by protecting stalled or damaged replication forks. After the induction of replication stress, required for the stabilization of stalled replication forks, the efficient activation of the intra- S-phase and G/2M cell-cycle checkpoints and the maintenance of genome stability | Down syndrome critical region gene 3; Belongs to the VPS26 family | 0.504 |
DONSON | GART | ENSP00000307143 | ENSP00000371253 | Protein downstream neighbor of Son; Replisome component that maintains genome stability by protecting stalled or damaged replication forks. After the induction of replication stress, required for the stabilization of stalled replication forks, the efficient activation of the intra- S-phase and G/2M cell-cycle checkpoints and the maintenance of genome stability | Trifunctional purine biosynthetic protein adenosine-3; Phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase; In the central section; belongs to the AIR synthase family | 0.828 |
DONSON | MRPS6 | ENSP00000307143 | ENSP00000382250 | Protein downstream neighbor of Son; Replisome component that maintains genome stability by protecting stalled or damaged replication forks. After the induction of replication stress, required for the stabilization of stalled replication forks, the efficient activation of the intra- S-phase and G/2M cell-cycle checkpoints and the maintenance of genome stability | Mitochondrial ribosomal protein S6 | 0.669 |
DONSON | PAXBP1 | ENSP00000307143 | ENSP00000328992 | Protein downstream neighbor of Son; Replisome component that maintains genome stability by protecting stalled or damaged replication forks. After the induction of replication stress, required for the stabilization of stalled replication forks, the efficient activation of the intra- S-phase and G/2M cell-cycle checkpoints and the maintenance of genome stability | PAX3- and PAX7-binding protein 1; Adapter protein linking the transcription factors PAX3 and PAX7 to the histone methylation machinery and involved in myogenesis. Associates with a histone methyltransferase complex that specifically mediates dimethylation and trimethylation of ’Lys-4’ of histone H3. Mediates the recruitment of that complex to the transcription factors PAX3 and PAX7 on chromatin to regulate the expression of genes involved in muscle progenitor cells proliferation including ID3 and CDC20 (By similarity) | 0.558 |
DONSON | TMEM50B | ENSP00000307143 | ENSP00000439768 | Protein downstream neighbor of Son; Replisome component that maintains genome stability by protecting stalled or damaged replication forks. After the induction of replication stress, required for the stabilization of stalled replication forks, the efficient activation of the intra- S-phase and G/2M cell-cycle checkpoints and the maintenance of genome stability | Transmembrane protein 50B | 0.751 |
DOPEY2 | DONSON | ENSP00000382104 | ENSP00000307143 | Protein dopey-2; May be involved in protein traffic between late Golgi and early endosomes; Belongs to the dopey family | Protein downstream neighbor of Son; Replisome component that maintains genome stability by protecting stalled or damaged replication forks. After the induction of replication stress, required for the stabilization of stalled replication forks, the efficient activation of the intra- S-phase and G/2M cell-cycle checkpoints and the maintenance of genome stability | 0.479 |
DOPEY2 | DSCR3 | ENSP00000382104 | ENSP00000311399 | Protein dopey-2; May be involved in protein traffic between late Golgi and early endosomes; Belongs to the dopey family | Down syndrome critical region gene 3; Belongs to the VPS26 family | 0.449 |
DOPEY2 | MRPS6 | ENSP00000382104 | ENSP00000382250 | Protein dopey-2; May be involved in protein traffic between late Golgi and early endosomes; Belongs to the dopey family | Mitochondrial ribosomal protein S6 | 0.593 |
DOPEY2 | PAXBP1 | ENSP00000382104 | ENSP00000328992 | Protein dopey-2; May be involved in protein traffic between late Golgi and early endosomes; Belongs to the dopey family | PAX3- and PAX7-binding protein 1; Adapter protein linking the transcription factors PAX3 and PAX7 to the histone methylation machinery and involved in myogenesis. Associates with a histone methyltransferase complex that specifically mediates dimethylation and trimethylation of ’Lys-4’ of histone H3. Mediates the recruitment of that complex to the transcription factors PAX3 and PAX7 on chromatin to regulate the expression of genes involved in muscle progenitor cells proliferation including ID3 and CDC20 (By similarity) | 0.558 |
DOPEY2 | TMEM50B | ENSP00000382104 | ENSP00000439768 | Protein dopey-2; May be involved in protein traffic between late Golgi and early endosomes; Belongs to the dopey family | Transmembrane protein 50B | 0.604 |
DSCR3 | DONSON | ENSP00000311399 | ENSP00000307143 | Down syndrome critical region gene 3; Belongs to the VPS26 family | Protein downstream neighbor of Son; Replisome component that maintains genome stability by protecting stalled or damaged replication forks. After the induction of replication stress, required for the stabilization of stalled replication forks, the efficient activation of the intra- S-phase and G/2M cell-cycle checkpoints and the maintenance of genome stability | 0.504 |
DSCR3 | DOPEY2 | ENSP00000311399 | ENSP00000382104 | Down syndrome critical region gene 3; Belongs to the VPS26 family | Protein dopey-2; May be involved in protein traffic between late Golgi and early endosomes; Belongs to the dopey family | 0.449 |
DSCR3 | GART | ENSP00000311399 | ENSP00000371253 | Down syndrome critical region gene 3; Belongs to the VPS26 family | Trifunctional purine biosynthetic protein adenosine-3; Phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase; In the central section; belongs to the AIR synthase family | 0.477 |