node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CREBL2 | DUSP16 | ENSP00000228865 | ENSP00000298573 | cAMP-responsive element-binding protein-like 2; Probable regulator of CREB1 transcriptional activity which is involved in adipose cells differentiation. May also play a regulatory role in the cell cycle. Identification in a chromosomal region frequently deleted in various cancers suggests that it might act as a tumor suppressor; Belongs to the bZIP family. ATF subfamily | Dual specificity protein phosphatase 16; Dual specificity protein phosphatase involved in the inactivation of MAP kinases. Dephosphorylates MAPK10 bound to ARRB2; Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily | 0.586 |
CREBL2 | KIAA1467 | ENSP00000228865 | ENSP00000197268 | cAMP-responsive element-binding protein-like 2; Probable regulator of CREB1 transcriptional activity which is involved in adipose cells differentiation. May also play a regulatory role in the cell cycle. Identification in a chromosomal region frequently deleted in various cancers suggests that it might act as a tumor suppressor; Belongs to the bZIP family. ATF subfamily | Protein FAM234B; KIAA1467 | 0.530 |
CREBL2 | LOH12CR1 | ENSP00000228865 | ENSP00000321546 | cAMP-responsive element-binding protein-like 2; Probable regulator of CREB1 transcriptional activity which is involved in adipose cells differentiation. May also play a regulatory role in the cell cycle. Identification in a chromosomal region frequently deleted in various cancers suggests that it might act as a tumor suppressor; Belongs to the bZIP family. ATF subfamily | BLOC-1-related complex subunit 5; As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor. Thereby, it may indirectly play a role in cell spreading and motility | 0.853 |
CREBL2 | MANSC1 | ENSP00000228865 | ENSP00000438205 | cAMP-responsive element-binding protein-like 2; Probable regulator of CREB1 transcriptional activity which is involved in adipose cells differentiation. May also play a regulatory role in the cell cycle. Identification in a chromosomal region frequently deleted in various cancers suggests that it might act as a tumor suppressor; Belongs to the bZIP family. ATF subfamily | MANSC domain containing 1 | 0.634 |
CREBL2 | MS4A15 | ENSP00000228865 | ENSP00000386022 | cAMP-responsive element-binding protein-like 2; Probable regulator of CREB1 transcriptional activity which is involved in adipose cells differentiation. May also play a regulatory role in the cell cycle. Identification in a chromosomal region frequently deleted in various cancers suggests that it might act as a tumor suppressor; Belongs to the bZIP family. ATF subfamily | Membrane-spanning 4-domains subfamily A member 15; May be involved in signal transduction as a component of a multimeric receptor complex; Membrane spanning 4-domains | 0.441 |
CREBL2 | PPM1N | ENSP00000228865 | ENSP00000397050 | cAMP-responsive element-binding protein-like 2; Probable regulator of CREB1 transcriptional activity which is involved in adipose cells differentiation. May also play a regulatory role in the cell cycle. Identification in a chromosomal region frequently deleted in various cancers suggests that it might act as a tumor suppressor; Belongs to the bZIP family. ATF subfamily | Protein phosphatase, Mg2+/Mn2+ dependent 1N | 0.430 |
CREBL2 | PPP1R37 | ENSP00000228865 | ENSP00000221462 | cAMP-responsive element-binding protein-like 2; Probable regulator of CREB1 transcriptional activity which is involved in adipose cells differentiation. May also play a regulatory role in the cell cycle. Identification in a chromosomal region frequently deleted in various cancers suggests that it might act as a tumor suppressor; Belongs to the bZIP family. ATF subfamily | Protein phosphatase 1 regulatory subunit 37; Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes; Belongs to the PPP1R37 family | 0.440 |
DUSP16 | CREBL2 | ENSP00000298573 | ENSP00000228865 | Dual specificity protein phosphatase 16; Dual specificity protein phosphatase involved in the inactivation of MAP kinases. Dephosphorylates MAPK10 bound to ARRB2; Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily | cAMP-responsive element-binding protein-like 2; Probable regulator of CREB1 transcriptional activity which is involved in adipose cells differentiation. May also play a regulatory role in the cell cycle. Identification in a chromosomal region frequently deleted in various cancers suggests that it might act as a tumor suppressor; Belongs to the bZIP family. ATF subfamily | 0.586 |
DUSP16 | LOH12CR1 | ENSP00000298573 | ENSP00000321546 | Dual specificity protein phosphatase 16; Dual specificity protein phosphatase involved in the inactivation of MAP kinases. Dephosphorylates MAPK10 bound to ARRB2; Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily | BLOC-1-related complex subunit 5; As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor. Thereby, it may indirectly play a role in cell spreading and motility | 0.607 |
DUSP16 | MANSC1 | ENSP00000298573 | ENSP00000438205 | Dual specificity protein phosphatase 16; Dual specificity protein phosphatase involved in the inactivation of MAP kinases. Dephosphorylates MAPK10 bound to ARRB2; Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily | MANSC domain containing 1 | 0.517 |
KIAA1467 | CREBL2 | ENSP00000197268 | ENSP00000228865 | Protein FAM234B; KIAA1467 | cAMP-responsive element-binding protein-like 2; Probable regulator of CREB1 transcriptional activity which is involved in adipose cells differentiation. May also play a regulatory role in the cell cycle. Identification in a chromosomal region frequently deleted in various cancers suggests that it might act as a tumor suppressor; Belongs to the bZIP family. ATF subfamily | 0.530 |
KIAA1467 | LOH12CR1 | ENSP00000197268 | ENSP00000321546 | Protein FAM234B; KIAA1467 | BLOC-1-related complex subunit 5; As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor. Thereby, it may indirectly play a role in cell spreading and motility | 0.442 |
KIAA1467 | MANSC1 | ENSP00000197268 | ENSP00000438205 | Protein FAM234B; KIAA1467 | MANSC domain containing 1 | 0.576 |
LDLRAD1 | MANSC1 | ENSP00000360411 | ENSP00000438205 | Low density lipoprotein receptor class A domain containing 1 | MANSC domain containing 1 | 0.585 |
LOH12CR1 | CREBL2 | ENSP00000321546 | ENSP00000228865 | BLOC-1-related complex subunit 5; As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor. Thereby, it may indirectly play a role in cell spreading and motility | cAMP-responsive element-binding protein-like 2; Probable regulator of CREB1 transcriptional activity which is involved in adipose cells differentiation. May also play a regulatory role in the cell cycle. Identification in a chromosomal region frequently deleted in various cancers suggests that it might act as a tumor suppressor; Belongs to the bZIP family. ATF subfamily | 0.853 |
LOH12CR1 | DUSP16 | ENSP00000321546 | ENSP00000298573 | BLOC-1-related complex subunit 5; As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor. Thereby, it may indirectly play a role in cell spreading and motility | Dual specificity protein phosphatase 16; Dual specificity protein phosphatase involved in the inactivation of MAP kinases. Dephosphorylates MAPK10 bound to ARRB2; Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily | 0.607 |
LOH12CR1 | KIAA1467 | ENSP00000321546 | ENSP00000197268 | BLOC-1-related complex subunit 5; As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor. Thereby, it may indirectly play a role in cell spreading and motility | Protein FAM234B; KIAA1467 | 0.442 |
LOH12CR1 | MANSC1 | ENSP00000321546 | ENSP00000438205 | BLOC-1-related complex subunit 5; As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor. Thereby, it may indirectly play a role in cell spreading and motility | MANSC domain containing 1 | 0.549 |
MANSC1 | CREBL2 | ENSP00000438205 | ENSP00000228865 | MANSC domain containing 1 | cAMP-responsive element-binding protein-like 2; Probable regulator of CREB1 transcriptional activity which is involved in adipose cells differentiation. May also play a regulatory role in the cell cycle. Identification in a chromosomal region frequently deleted in various cancers suggests that it might act as a tumor suppressor; Belongs to the bZIP family. ATF subfamily | 0.634 |
MANSC1 | DUSP16 | ENSP00000438205 | ENSP00000298573 | MANSC domain containing 1 | Dual specificity protein phosphatase 16; Dual specificity protein phosphatase involved in the inactivation of MAP kinases. Dephosphorylates MAPK10 bound to ARRB2; Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily | 0.517 |