| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| C18orf63 | SLFN12L | ENSP00000464330 | ENSP00000437635 | Uncharacterized protein C18orf63; Chromosome 18 open reading frame 63 | Schlafen family member 12 like; Belongs to the Schlafen family | 0.497 |
| CCDC146 | INAFM1 | ENSP00000285871 | ENSP00000447679 | Coiled-coil domain containing 146 | Putative transmembrane protein INAFM1; InaF motif containing 1 | 0.473 |
| CCDC146 | SLFN12L | ENSP00000285871 | ENSP00000437635 | Coiled-coil domain containing 146 | Schlafen family member 12 like; Belongs to the Schlafen family | 0.450 |
| CNP | HAND1 | ENSP00000377470 | ENSP00000231121 | 2’,3’-cyclic-nucleotide 3’-phosphodiesterase; May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin | Heart- and neural crest derivatives-expressed protein 1; Transcription factor that plays an essential role in both trophoblast-giant cells differentiation and in cardiac morphogenesis. In the adult, could be required for ongoing expression of cardiac-specific genes. Binds the DNA sequence 5’- NRTCTG-3’ (non-canonical E-box) (By similarity); Basic helix-loop-helix proteins | 0.639 |
| CNP | SLFN12L | ENSP00000377470 | ENSP00000437635 | 2’,3’-cyclic-nucleotide 3’-phosphodiesterase; May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin | Schlafen family member 12 like; Belongs to the Schlafen family | 0.537 |
| HAND1 | CNP | ENSP00000231121 | ENSP00000377470 | Heart- and neural crest derivatives-expressed protein 1; Transcription factor that plays an essential role in both trophoblast-giant cells differentiation and in cardiac morphogenesis. In the adult, could be required for ongoing expression of cardiac-specific genes. Binds the DNA sequence 5’- NRTCTG-3’ (non-canonical E-box) (By similarity); Basic helix-loop-helix proteins | 2’,3’-cyclic-nucleotide 3’-phosphodiesterase; May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin | 0.639 |
| HAND1 | SLFN12L | ENSP00000231121 | ENSP00000437635 | Heart- and neural crest derivatives-expressed protein 1; Transcription factor that plays an essential role in both trophoblast-giant cells differentiation and in cardiac morphogenesis. In the adult, could be required for ongoing expression of cardiac-specific genes. Binds the DNA sequence 5’- NRTCTG-3’ (non-canonical E-box) (By similarity); Basic helix-loop-helix proteins | Schlafen family member 12 like; Belongs to the Schlafen family | 0.451 |
| INAFM1 | CCDC146 | ENSP00000447679 | ENSP00000285871 | Putative transmembrane protein INAFM1; InaF motif containing 1 | Coiled-coil domain containing 146 | 0.473 |
| INAFM1 | SLFN12L | ENSP00000447679 | ENSP00000437635 | Putative transmembrane protein INAFM1; InaF motif containing 1 | Schlafen family member 12 like; Belongs to the Schlafen family | 0.476 |
| OAS2 | OAS3 | ENSP00000342278 | ENSP00000228928 | 2’-5’-oligoadenylate synthase 2; Interferon-induced, dsRNA-activated antiviral enzyme which plays a critical role in cellular innate antiviral response. In addition, it may also play a role in other cellular processes such as apoptosis, cell growth, differentiation and gene regulation. Synthesizes higher oligomers of 2’-5’-oligoadenylates (2-5A) from ATP which then bind to the inactive monomeric form of ribonuclease L (RNase L) leading to its dimerization and subsequent activation. Activation of RNase L leads to degradation of cellular as well as viral RNA, resulting in the inhibition [...] | 2’-5’-oligoadenylate synthase 3; Interferon-induced, dsRNA-activated antiviral enzyme which plays a critical role in cellular innate antiviral response. In addition, it may also play a role in other cellular processes such as apoptosis, cell growth, differentiation and gene regulation. Synthesizes preferentially dimers of 2’-5’- oligoadenylates (2-5A) from ATP which then bind to the inactive monomeric form of ribonuclease L (RNase L) leading to its dimerization and subsequent activation. Activation of RNase L leads to degradation of cellular as well as viral RNA, resulting in the inhib [...] | 0.957 |
| OAS2 | SLFN12L | ENSP00000342278 | ENSP00000437635 | 2’-5’-oligoadenylate synthase 2; Interferon-induced, dsRNA-activated antiviral enzyme which plays a critical role in cellular innate antiviral response. In addition, it may also play a role in other cellular processes such as apoptosis, cell growth, differentiation and gene regulation. Synthesizes higher oligomers of 2’-5’-oligoadenylates (2-5A) from ATP which then bind to the inactive monomeric form of ribonuclease L (RNase L) leading to its dimerization and subsequent activation. Activation of RNase L leads to degradation of cellular as well as viral RNA, resulting in the inhibition [...] | Schlafen family member 12 like; Belongs to the Schlafen family | 0.444 |
| OAS3 | OAS2 | ENSP00000228928 | ENSP00000342278 | 2’-5’-oligoadenylate synthase 3; Interferon-induced, dsRNA-activated antiviral enzyme which plays a critical role in cellular innate antiviral response. In addition, it may also play a role in other cellular processes such as apoptosis, cell growth, differentiation and gene regulation. Synthesizes preferentially dimers of 2’-5’- oligoadenylates (2-5A) from ATP which then bind to the inactive monomeric form of ribonuclease L (RNase L) leading to its dimerization and subsequent activation. Activation of RNase L leads to degradation of cellular as well as viral RNA, resulting in the inhib [...] | 2’-5’-oligoadenylate synthase 2; Interferon-induced, dsRNA-activated antiviral enzyme which plays a critical role in cellular innate antiviral response. In addition, it may also play a role in other cellular processes such as apoptosis, cell growth, differentiation and gene regulation. Synthesizes higher oligomers of 2’-5’-oligoadenylates (2-5A) from ATP which then bind to the inactive monomeric form of ribonuclease L (RNase L) leading to its dimerization and subsequent activation. Activation of RNase L leads to degradation of cellular as well as viral RNA, resulting in the inhibition [...] | 0.957 |
| OAS3 | SLFN12L | ENSP00000228928 | ENSP00000437635 | 2’-5’-oligoadenylate synthase 3; Interferon-induced, dsRNA-activated antiviral enzyme which plays a critical role in cellular innate antiviral response. In addition, it may also play a role in other cellular processes such as apoptosis, cell growth, differentiation and gene regulation. Synthesizes preferentially dimers of 2’-5’- oligoadenylates (2-5A) from ATP which then bind to the inactive monomeric form of ribonuclease L (RNase L) leading to its dimerization and subsequent activation. Activation of RNase L leads to degradation of cellular as well as viral RNA, resulting in the inhib [...] | Schlafen family member 12 like; Belongs to the Schlafen family | 0.614 |
| SLFN12L | C18orf63 | ENSP00000437635 | ENSP00000464330 | Schlafen family member 12 like; Belongs to the Schlafen family | Uncharacterized protein C18orf63; Chromosome 18 open reading frame 63 | 0.497 |
| SLFN12L | CCDC146 | ENSP00000437635 | ENSP00000285871 | Schlafen family member 12 like; Belongs to the Schlafen family | Coiled-coil domain containing 146 | 0.450 |
| SLFN12L | CNP | ENSP00000437635 | ENSP00000377470 | Schlafen family member 12 like; Belongs to the Schlafen family | 2’,3’-cyclic-nucleotide 3’-phosphodiesterase; May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin | 0.537 |
| SLFN12L | HAND1 | ENSP00000437635 | ENSP00000231121 | Schlafen family member 12 like; Belongs to the Schlafen family | Heart- and neural crest derivatives-expressed protein 1; Transcription factor that plays an essential role in both trophoblast-giant cells differentiation and in cardiac morphogenesis. In the adult, could be required for ongoing expression of cardiac-specific genes. Binds the DNA sequence 5’- NRTCTG-3’ (non-canonical E-box) (By similarity); Basic helix-loop-helix proteins | 0.451 |
| SLFN12L | INAFM1 | ENSP00000437635 | ENSP00000447679 | Schlafen family member 12 like; Belongs to the Schlafen family | Putative transmembrane protein INAFM1; InaF motif containing 1 | 0.476 |
| SLFN12L | OAS2 | ENSP00000437635 | ENSP00000342278 | Schlafen family member 12 like; Belongs to the Schlafen family | 2’-5’-oligoadenylate synthase 2; Interferon-induced, dsRNA-activated antiviral enzyme which plays a critical role in cellular innate antiviral response. In addition, it may also play a role in other cellular processes such as apoptosis, cell growth, differentiation and gene regulation. Synthesizes higher oligomers of 2’-5’-oligoadenylates (2-5A) from ATP which then bind to the inactive monomeric form of ribonuclease L (RNase L) leading to its dimerization and subsequent activation. Activation of RNase L leads to degradation of cellular as well as viral RNA, resulting in the inhibition [...] | 0.444 |
| SLFN12L | OAS3 | ENSP00000437635 | ENSP00000228928 | Schlafen family member 12 like; Belongs to the Schlafen family | 2’-5’-oligoadenylate synthase 3; Interferon-induced, dsRNA-activated antiviral enzyme which plays a critical role in cellular innate antiviral response. In addition, it may also play a role in other cellular processes such as apoptosis, cell growth, differentiation and gene regulation. Synthesizes preferentially dimers of 2’-5’- oligoadenylates (2-5A) from ATP which then bind to the inactive monomeric form of ribonuclease L (RNase L) leading to its dimerization and subsequent activation. Activation of RNase L leads to degradation of cellular as well as viral RNA, resulting in the inhib [...] | 0.614 |
