node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C16orf93 | ERICH1 | ENSP00000437532 | ENSP00000262109 | Coiled-coil domain-containing protein 189; Chromosome 16 open reading frame 93 | Glutamate-rich protein 1; Glutamate rich 1 | 0.420 |
C16orf93 | FAM53A | ENSP00000437532 | ENSP00000310057 | Coiled-coil domain-containing protein 189; Chromosome 16 open reading frame 93 | Protein FAM53A; May play an important role in neural development; the dorsomedial roof of the third ventricle | 0.669 |
C16orf93 | NACC1 | ENSP00000437532 | ENSP00000292431 | Coiled-coil domain-containing protein 189; Chromosome 16 open reading frame 93 | Nucleus accumbens-associated protein 1; Functions as a transcriptional repressor. Seems to function as a transcriptional corepressor in neuronal cells through recruitment of HDAC3 and HDAC4. Contributes to tumor progression, and tumor cell proliferation and survival. This may be mediated at least in part through repressing transcriptional activity of GADD45GIP1. Required for recruiting the proteasome from the nucleus to the cytoplasm and dendritic spines; BEN domain containing | 0.530 |
C16orf93 | NRG4 | ENSP00000437532 | ENSP00000378367 | Coiled-coil domain-containing protein 189; Chromosome 16 open reading frame 93 | Pro-neuregulin-4, membrane-bound isoform; Low affinity ligand for the ERBB4 tyrosine kinase receptor. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. Does not bind to the ERBB1, ERBB2 and ERBB3 receptors (By similarity) | 0.619 |
C16orf93 | PRSS53 | ENSP00000437532 | ENSP00000280606 | Coiled-coil domain-containing protein 189; Chromosome 16 open reading frame 93 | Serine protease 53; In vitro can degrade the fibrinogen alpha chain of as well as pro-urokinase-type plasminogen activator; Serine proteases | 0.623 |
C16orf93 | RTBDN | ENSP00000437532 | ENSP00000326253 | Coiled-coil domain-containing protein 189; Chromosome 16 open reading frame 93 | Retbindin; Riboflavin-binding protein which might have a role in retinal flavin transport | 0.495 |
C16orf93 | SCGB1D2 | ENSP00000437532 | ENSP00000244926 | Coiled-coil domain-containing protein 189; Chromosome 16 open reading frame 93 | Secretoglobin family 1D member 2; May bind androgens and other steroids, may also bind estramustine, a chemotherapeutic agent used for prostate cancer. May be under transcriptional regulation of steroid hormones; Secretoglobins | 0.622 |
C16orf93 | TTC9B | ENSP00000437532 | ENSP00000311760 | Coiled-coil domain-containing protein 189; Chromosome 16 open reading frame 93 | Tetratricopeptide repeat domain containing | 0.428 |
ERICH1 | C16orf93 | ENSP00000262109 | ENSP00000437532 | Glutamate-rich protein 1; Glutamate rich 1 | Coiled-coil domain-containing protein 189; Chromosome 16 open reading frame 93 | 0.420 |
ERICH1 | RTBDN | ENSP00000262109 | ENSP00000326253 | Glutamate-rich protein 1; Glutamate rich 1 | Retbindin; Riboflavin-binding protein which might have a role in retinal flavin transport | 0.539 |
ERICH1 | TTC9B | ENSP00000262109 | ENSP00000311760 | Glutamate-rich protein 1; Glutamate rich 1 | Tetratricopeptide repeat domain containing | 0.514 |
FAM53A | C16orf93 | ENSP00000310057 | ENSP00000437532 | Protein FAM53A; May play an important role in neural development; the dorsomedial roof of the third ventricle | Coiled-coil domain-containing protein 189; Chromosome 16 open reading frame 93 | 0.669 |
FAM53A | PRSS53 | ENSP00000310057 | ENSP00000280606 | Protein FAM53A; May play an important role in neural development; the dorsomedial roof of the third ventricle | Serine protease 53; In vitro can degrade the fibrinogen alpha chain of as well as pro-urokinase-type plasminogen activator; Serine proteases | 0.461 |
NACC1 | C16orf93 | ENSP00000292431 | ENSP00000437532 | Nucleus accumbens-associated protein 1; Functions as a transcriptional repressor. Seems to function as a transcriptional corepressor in neuronal cells through recruitment of HDAC3 and HDAC4. Contributes to tumor progression, and tumor cell proliferation and survival. This may be mediated at least in part through repressing transcriptional activity of GADD45GIP1. Required for recruiting the proteasome from the nucleus to the cytoplasm and dendritic spines; BEN domain containing | Coiled-coil domain-containing protein 189; Chromosome 16 open reading frame 93 | 0.530 |
NRG4 | C16orf93 | ENSP00000378367 | ENSP00000437532 | Pro-neuregulin-4, membrane-bound isoform; Low affinity ligand for the ERBB4 tyrosine kinase receptor. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. Does not bind to the ERBB1, ERBB2 and ERBB3 receptors (By similarity) | Coiled-coil domain-containing protein 189; Chromosome 16 open reading frame 93 | 0.619 |
PRSS53 | C16orf93 | ENSP00000280606 | ENSP00000437532 | Serine protease 53; In vitro can degrade the fibrinogen alpha chain of as well as pro-urokinase-type plasminogen activator; Serine proteases | Coiled-coil domain-containing protein 189; Chromosome 16 open reading frame 93 | 0.623 |
PRSS53 | FAM53A | ENSP00000280606 | ENSP00000310057 | Serine protease 53; In vitro can degrade the fibrinogen alpha chain of as well as pro-urokinase-type plasminogen activator; Serine proteases | Protein FAM53A; May play an important role in neural development; the dorsomedial roof of the third ventricle | 0.461 |
RTBDN | C16orf93 | ENSP00000326253 | ENSP00000437532 | Retbindin; Riboflavin-binding protein which might have a role in retinal flavin transport | Coiled-coil domain-containing protein 189; Chromosome 16 open reading frame 93 | 0.495 |
RTBDN | ERICH1 | ENSP00000326253 | ENSP00000262109 | Retbindin; Riboflavin-binding protein which might have a role in retinal flavin transport | Glutamate-rich protein 1; Glutamate rich 1 | 0.539 |
RTBDN | TTC9B | ENSP00000326253 | ENSP00000311760 | Retbindin; Riboflavin-binding protein which might have a role in retinal flavin transport | Tetratricopeptide repeat domain containing | 0.584 |