C11orf48 protein (human) - STRING database

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C11orf48

LBH domain-containing protein 1; Chromosome 11 open reading frame 48 (263 aa)

Predicted Functional Partners:

C11orf44

0.733

METTL12

0.642

ARCN1

0.524

TXNL1

0.501

ANKFY1

0.440

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANKFY1	C11orf48	ENSP00000459943	ENSP00000436848	Rabankyrin-5; Proposed effector of Rab5. Binds to phosphatidylinositol 3-phosphate (PI(3)P). Involved in homotypic early endosome fusion and to a lesser extent in heterotypic fusion of chlathrin-coated vesicles with early endosomes. Involved in macropinocytosis; the function is dependent on Rab5-GTP. Required for correct endosomal localization. Involved in the internalization and trafficking of activated tyrosine kinase receptors such as PDGFRB. Regulates the subcellular localization of the retromer complex in a EHD1- dependent manner. Involved in endosome-to-Golgi transport and biosyn [...]	LBH domain-containing protein 1; Chromosome 11 open reading frame 48	0.440
ARCN1	C11orf48	ENSP00000264028	ENSP00000436848	Coatomer subunit delta; Component of the coatomer, a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the co [...]	LBH domain-containing protein 1; Chromosome 11 open reading frame 48	0.524
ARCN1	TXNL1	ENSP00000264028	ENSP00000217515	Coatomer subunit delta; Component of the coatomer, a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the co [...]	Thioredoxin-like protein 1; Active thioredoxin with a redox potential of about -250 mV	0.414
C11orf44	C11orf48	ENSP00000485399	ENSP00000436848	Uncharacterized protein C11orf44; Chromosome 11 open reading frame 44	LBH domain-containing protein 1; Chromosome 11 open reading frame 48	0.733
C11orf44	METTL12	ENSP00000485399	ENSP00000431287	Uncharacterized protein C11orf44; Chromosome 11 open reading frame 44	Methyltransferase-like protein 12, mitochondrial; Putative methyltransferase	0.668
C11orf48	ANKFY1	ENSP00000436848	ENSP00000459943	LBH domain-containing protein 1; Chromosome 11 open reading frame 48	Rabankyrin-5; Proposed effector of Rab5. Binds to phosphatidylinositol 3-phosphate (PI(3)P). Involved in homotypic early endosome fusion and to a lesser extent in heterotypic fusion of chlathrin-coated vesicles with early endosomes. Involved in macropinocytosis; the function is dependent on Rab5-GTP. Required for correct endosomal localization. Involved in the internalization and trafficking of activated tyrosine kinase receptors such as PDGFRB. Regulates the subcellular localization of the retromer complex in a EHD1- dependent manner. Involved in endosome-to-Golgi transport and biosyn [...]	0.440
C11orf48	ARCN1	ENSP00000436848	ENSP00000264028	LBH domain-containing protein 1; Chromosome 11 open reading frame 48	Coatomer subunit delta; Component of the coatomer, a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the co [...]	0.524
C11orf48	C11orf44	ENSP00000436848	ENSP00000485399	LBH domain-containing protein 1; Chromosome 11 open reading frame 48	Uncharacterized protein C11orf44; Chromosome 11 open reading frame 44	0.733
C11orf48	METTL12	ENSP00000436848	ENSP00000431287	LBH domain-containing protein 1; Chromosome 11 open reading frame 48	Methyltransferase-like protein 12, mitochondrial; Putative methyltransferase	0.642
C11orf48	TXNL1	ENSP00000436848	ENSP00000217515	LBH domain-containing protein 1; Chromosome 11 open reading frame 48	Thioredoxin-like protein 1; Active thioredoxin with a redox potential of about -250 mV	0.501
METTL12	C11orf44	ENSP00000431287	ENSP00000485399	Methyltransferase-like protein 12, mitochondrial; Putative methyltransferase	Uncharacterized protein C11orf44; Chromosome 11 open reading frame 44	0.668
METTL12	C11orf48	ENSP00000431287	ENSP00000436848	Methyltransferase-like protein 12, mitochondrial; Putative methyltransferase	LBH domain-containing protein 1; Chromosome 11 open reading frame 48	0.642
TXNL1	ARCN1	ENSP00000217515	ENSP00000264028	Thioredoxin-like protein 1; Active thioredoxin with a redox potential of about -250 mV	Coatomer subunit delta; Component of the coatomer, a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the co [...]	0.414
TXNL1	C11orf48	ENSP00000217515	ENSP00000436848	Thioredoxin-like protein 1; Active thioredoxin with a redox potential of about -250 mV	LBH domain-containing protein 1; Chromosome 11 open reading frame 48	0.501

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