| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACADM | FARSB | ENSP00000359871 | ENSP00000281828 | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial; Acyl-CoA dehydrogenase specific for acyl chain lengths of 4 to 16 that catalyzes the initial step of fatty acid beta- oxidation. Utilizes the electron transfer flavoprotein (ETF) as an electron acceptor to transfer electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) | phenylalanyl-tRNA synthetase beta subunit; Aminoacyl tRNA synthetases, Class II | 0.548 |
| ACADM | KIAA0100 | ENSP00000359871 | ENSP00000436773 | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial; Acyl-CoA dehydrogenase specific for acyl chain lengths of 4 to 16 that catalyzes the initial step of fatty acid beta- oxidation. Utilizes the electron transfer flavoprotein (ETF) as an electron acceptor to transfer electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) | Protein KIAA0100; May be involved in membrane trafficking; Belongs to the SABRE family | 0.548 |
| FARSB | ACADM | ENSP00000281828 | ENSP00000359871 | phenylalanyl-tRNA synthetase beta subunit; Aminoacyl tRNA synthetases, Class II | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial; Acyl-CoA dehydrogenase specific for acyl chain lengths of 4 to 16 that catalyzes the initial step of fatty acid beta- oxidation. Utilizes the electron transfer flavoprotein (ETF) as an electron acceptor to transfer electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) | 0.548 |
| FARSB | KIAA0100 | ENSP00000281828 | ENSP00000436773 | phenylalanyl-tRNA synthetase beta subunit; Aminoacyl tRNA synthetases, Class II | Protein KIAA0100; May be involved in membrane trafficking; Belongs to the SABRE family | 0.548 |
| FARSB | PXMP4 | ENSP00000281828 | ENSP00000386385 | phenylalanyl-tRNA synthetase beta subunit; Aminoacyl tRNA synthetases, Class II | Peroxisomal membrane protein 4 | 0.548 |
| HTATSF1 | KIAA0100 | ENSP00000442699 | ENSP00000436773 | HIV Tat-specific factor 1; Functions as a general transcription factor playing a role in the process of transcriptional elongation. May mediate the reciprocal stimulatory effect of splicing on transcriptional elongation. In case of infection by HIV-1, it is up-regulated by the HIV-1 proteins NEF and gp120, acts as a cofactor required for the Tat-enhanced transcription of the virus; RNA binding motif containing | Protein KIAA0100; May be involved in membrane trafficking; Belongs to the SABRE family | 0.551 |
| KATNB1 | KATNBL1 | ENSP00000368982 | ENSP00000256544 | Katanin p80 WD40 repeat-containing subunit B1; Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Micr [...] | KATNB1-like protein 1; Regulates microtubule-severing activity of KATNAL1 in a concentration-dependent manner in vitro | 0.886 |
| KATNB1 | KIAA0100 | ENSP00000368982 | ENSP00000436773 | Katanin p80 WD40 repeat-containing subunit B1; Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Micr [...] | Protein KIAA0100; May be involved in membrane trafficking; Belongs to the SABRE family | 0.577 |
| KATNBL1 | KATNB1 | ENSP00000256544 | ENSP00000368982 | KATNB1-like protein 1; Regulates microtubule-severing activity of KATNAL1 in a concentration-dependent manner in vitro | Katanin p80 WD40 repeat-containing subunit B1; Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Micr [...] | 0.886 |
| KATNBL1 | KIAA0100 | ENSP00000256544 | ENSP00000436773 | KATNB1-like protein 1; Regulates microtubule-severing activity of KATNAL1 in a concentration-dependent manner in vitro | Protein KIAA0100; May be involved in membrane trafficking; Belongs to the SABRE family | 0.606 |
| KIAA0100 | ACADM | ENSP00000436773 | ENSP00000359871 | Protein KIAA0100; May be involved in membrane trafficking; Belongs to the SABRE family | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial; Acyl-CoA dehydrogenase specific for acyl chain lengths of 4 to 16 that catalyzes the initial step of fatty acid beta- oxidation. Utilizes the electron transfer flavoprotein (ETF) as an electron acceptor to transfer electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) | 0.548 |
| KIAA0100 | FARSB | ENSP00000436773 | ENSP00000281828 | Protein KIAA0100; May be involved in membrane trafficking; Belongs to the SABRE family | phenylalanyl-tRNA synthetase beta subunit; Aminoacyl tRNA synthetases, Class II | 0.548 |
| KIAA0100 | HTATSF1 | ENSP00000436773 | ENSP00000442699 | Protein KIAA0100; May be involved in membrane trafficking; Belongs to the SABRE family | HIV Tat-specific factor 1; Functions as a general transcription factor playing a role in the process of transcriptional elongation. May mediate the reciprocal stimulatory effect of splicing on transcriptional elongation. In case of infection by HIV-1, it is up-regulated by the HIV-1 proteins NEF and gp120, acts as a cofactor required for the Tat-enhanced transcription of the virus; RNA binding motif containing | 0.551 |
| KIAA0100 | KATNB1 | ENSP00000436773 | ENSP00000368982 | Protein KIAA0100; May be involved in membrane trafficking; Belongs to the SABRE family | Katanin p80 WD40 repeat-containing subunit B1; Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Micr [...] | 0.577 |
| KIAA0100 | KATNBL1 | ENSP00000436773 | ENSP00000256544 | Protein KIAA0100; May be involved in membrane trafficking; Belongs to the SABRE family | KATNB1-like protein 1; Regulates microtubule-severing activity of KATNAL1 in a concentration-dependent manner in vitro | 0.606 |
| KIAA0100 | MOXD1 | ENSP00000436773 | ENSP00000356940 | Protein KIAA0100; May be involved in membrane trafficking; Belongs to the SABRE family | Monooxygenase DBH like 1; Belongs to the copper type II ascorbate-dependent monooxygenase family | 0.634 |
| KIAA0100 | PXMP4 | ENSP00000436773 | ENSP00000386385 | Protein KIAA0100; May be involved in membrane trafficking; Belongs to the SABRE family | Peroxisomal membrane protein 4 | 0.548 |
| KIAA0100 | SETX | ENSP00000436773 | ENSP00000224140 | Protein KIAA0100; May be involved in membrane trafficking; Belongs to the SABRE family | Probable helicase senataxin; Probable RNA/DNA helicase involved in diverse aspects of RNA metabolism and genomic integrity. Plays a role in transcription regulation by its ability to modulate RNA Polymerase II (Pol II) binding to chromatin and through its interaction with proteins involved in transcription. Contributes to the mRNA splicing efficiency and splice site selection. Required for the resolution of R-loop RNA-DNA hybrid formation at G-rich pause sites located downstream of the poly(A) site, allowing XRN2 recruitment and XRN2-mediated degradation of the downstream cleaved RNA a [...] | 0.539 |
| KIAA0100 | SSU72 | ENSP00000436773 | ENSP00000291386 | Protein KIAA0100; May be involved in membrane trafficking; Belongs to the SABRE family | RNA polymerase II subunit A C-terminal domain phosphatase SSU72; Protein phosphatase that catalyzes the dephosphorylation of the C-terminal domain of RNA polymerase II. Plays a role in RNA processing and termination. Plays a role in pre-mRNA polyadenylation via its interaction with SYMPK; Belongs to the SSU72 phosphatase family | 0.618 |
| KIAA0100 | TRAPPC11 | ENSP00000436773 | ENSP00000335371 | Protein KIAA0100; May be involved in membrane trafficking; Belongs to the SABRE family | Trafficking protein particle complex subunit 11; Involved in endoplasmic reticulum to Golgi apparatus trafficking at a very early stage; Trafficking protein particle complex | 0.580 |
