ZSCAN5C protein (human) - STRING database

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ZSCAN5C

Putative zinc finger and SCAN domain-containing protein 5C; May be involved in transcriptional regulation; SCAN domain containing (496 aa)

Predicted Functional Partners:

C16orf13

0.558

TRIM7

0.441

C17orf59

0.441

POLR3E

0.401

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C16orf13	C17orf59	ENSP00000440765	ENSP00000373669	Methyltransferase-like 26; Chromosome 16 open reading frame 13	BLOC-1-related complex subunit 6; As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor; Belongs to the BORCS6 family	0.653
C16orf13	TRIM7	ENSP00000440765	ENSP00000274773	Methyltransferase-like 26; Chromosome 16 open reading frame 13	E3 ubiquitin-protein ligase TRIM7; E3 ubiquitin-protein ligase. Mediates ’Lys-63’-linked polyubiquitination and stabilization of the JUN coactivator RNF187 in response to growth factor signaling via the MEK/ERK pathway, thereby regulating JUN transactivation and cellular proliferation; Belongs to the TRIM/RBCC family	0.571
C16orf13	ZSCAN5C	ENSP00000440765	ENSP00000435234	Methyltransferase-like 26; Chromosome 16 open reading frame 13	Putative zinc finger and SCAN domain-containing protein 5C; May be involved in transcriptional regulation; SCAN domain containing	0.558
C17orf59	C16orf13	ENSP00000373669	ENSP00000440765	BLOC-1-related complex subunit 6; As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor; Belongs to the BORCS6 family	Methyltransferase-like 26; Chromosome 16 open reading frame 13	0.653
C17orf59	TRIM7	ENSP00000373669	ENSP00000274773	BLOC-1-related complex subunit 6; As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor; Belongs to the BORCS6 family	E3 ubiquitin-protein ligase TRIM7; E3 ubiquitin-protein ligase. Mediates ’Lys-63’-linked polyubiquitination and stabilization of the JUN coactivator RNF187 in response to growth factor signaling via the MEK/ERK pathway, thereby regulating JUN transactivation and cellular proliferation; Belongs to the TRIM/RBCC family	0.535
C17orf59	ZSCAN5C	ENSP00000373669	ENSP00000435234	BLOC-1-related complex subunit 6; As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor; Belongs to the BORCS6 family	Putative zinc finger and SCAN domain-containing protein 5C; May be involved in transcriptional regulation; SCAN domain containing	0.441
POLR3E	ZSCAN5C	ENSP00000299853	ENSP00000435234	DNA-directed RNA polymerase III subunit RPC5; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Essential for efficient transcription from both the type 2 VAI and type 3 U6 RNA polymerase III promoters. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA th [...]	Putative zinc finger and SCAN domain-containing protein 5C; May be involved in transcriptional regulation; SCAN domain containing	0.401
TRIM7	C16orf13	ENSP00000274773	ENSP00000440765	E3 ubiquitin-protein ligase TRIM7; E3 ubiquitin-protein ligase. Mediates ’Lys-63’-linked polyubiquitination and stabilization of the JUN coactivator RNF187 in response to growth factor signaling via the MEK/ERK pathway, thereby regulating JUN transactivation and cellular proliferation; Belongs to the TRIM/RBCC family	Methyltransferase-like 26; Chromosome 16 open reading frame 13	0.571
TRIM7	C17orf59	ENSP00000274773	ENSP00000373669	E3 ubiquitin-protein ligase TRIM7; E3 ubiquitin-protein ligase. Mediates ’Lys-63’-linked polyubiquitination and stabilization of the JUN coactivator RNF187 in response to growth factor signaling via the MEK/ERK pathway, thereby regulating JUN transactivation and cellular proliferation; Belongs to the TRIM/RBCC family	BLOC-1-related complex subunit 6; As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor; Belongs to the BORCS6 family	0.535
TRIM7	ZSCAN5C	ENSP00000274773	ENSP00000435234	E3 ubiquitin-protein ligase TRIM7; E3 ubiquitin-protein ligase. Mediates ’Lys-63’-linked polyubiquitination and stabilization of the JUN coactivator RNF187 in response to growth factor signaling via the MEK/ERK pathway, thereby regulating JUN transactivation and cellular proliferation; Belongs to the TRIM/RBCC family	Putative zinc finger and SCAN domain-containing protein 5C; May be involved in transcriptional regulation; SCAN domain containing	0.441
ZSCAN5C	C16orf13	ENSP00000435234	ENSP00000440765	Putative zinc finger and SCAN domain-containing protein 5C; May be involved in transcriptional regulation; SCAN domain containing	Methyltransferase-like 26; Chromosome 16 open reading frame 13	0.558
ZSCAN5C	C17orf59	ENSP00000435234	ENSP00000373669	Putative zinc finger and SCAN domain-containing protein 5C; May be involved in transcriptional regulation; SCAN domain containing	BLOC-1-related complex subunit 6; As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor; Belongs to the BORCS6 family	0.441
ZSCAN5C	POLR3E	ENSP00000435234	ENSP00000299853	Putative zinc finger and SCAN domain-containing protein 5C; May be involved in transcriptional regulation; SCAN domain containing	DNA-directed RNA polymerase III subunit RPC5; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Essential for efficient transcription from both the type 2 VAI and type 3 U6 RNA polymerase III promoters. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA th [...]	0.401
ZSCAN5C	TRIM7	ENSP00000435234	ENSP00000274773	Putative zinc finger and SCAN domain-containing protein 5C; May be involved in transcriptional regulation; SCAN domain containing	E3 ubiquitin-protein ligase TRIM7; E3 ubiquitin-protein ligase. Mediates ’Lys-63’-linked polyubiquitination and stabilization of the JUN coactivator RNF187 in response to growth factor signaling via the MEK/ERK pathway, thereby regulating JUN transactivation and cellular proliferation; Belongs to the TRIM/RBCC family	0.441

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