node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AQP3 | SLC43A3 | ENSP00000297991 | ENSP00000434515 | Aquaporin-3; Water channel required to promote glycerol permeability and water transport across cell membranes. Acts as a glycerol transporter in skin and plays an important role in regulating SC (stratum corneum) and epidermal glycerol content. Involved in skin hydration, wound healing, and tumorigenesis. Provides kidney medullary collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Slightly permeable to urea and may function as a water and urea exit mechanism in antidiuresis in collecting duct cells. It may play an [...] | Solute carrier family 43 member 3; Putative transporter; Belongs to the SLC43A transporter (TC 2.A.1.44) family | 0.433 |
AQP3 | SLC6A15 | ENSP00000297991 | ENSP00000266682 | Aquaporin-3; Water channel required to promote glycerol permeability and water transport across cell membranes. Acts as a glycerol transporter in skin and plays an important role in regulating SC (stratum corneum) and epidermal glycerol content. Involved in skin hydration, wound healing, and tumorigenesis. Provides kidney medullary collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Slightly permeable to urea and may function as a water and urea exit mechanism in antidiuresis in collecting duct cells. It may play an [...] | Sodium-dependent neutral amino acid transporter B(0)AT2; Functions as a sodium-dependent neutral amino acid transporter. Exhibits preference for the branched-chain amino acids, particularly leucine, valine and isoleucine and methionine. Mediates the saturable, pH-sensitive and electrogenic cotransport of proline and sodium ions with a stoichiometry of 1-1. May have a role as transporter for neurotransmitter precursors into neurons. In contrast to other members of the neurotransmitter transporter family, does not appear to be chloride-dependent; Solute carriers | 0.446 |
CSGALNACT2 | SLC43A3 | ENSP00000363590 | ENSP00000434515 | Chondroitin sulfate N-acetylgalactosaminyltransferase 2; Transfers 1,4-N-acetylgalactosamine (GalNAc) from UDP- GalNAc to the non-reducing end of glucuronic acid (GlcUA). Required for addition of the first GalNAc to the core tetrasaccharide linker and for elongation of chondroitin chains | Solute carrier family 43 member 3; Putative transporter; Belongs to the SLC43A transporter (TC 2.A.1.44) family | 0.471 |
ECT2L | SLC43A3 | ENSP00000442307 | ENSP00000434515 | Epithelial cell-transforming sequence 2 oncogene-like; May act as a guanine nucleotide exchange factor (GEF); F-boxes other | Solute carrier family 43 member 3; Putative transporter; Belongs to the SLC43A transporter (TC 2.A.1.44) family | 0.521 |
ENSG00000269881 | SLC43A3 | ENSP00000471331 | ENSP00000434515 | cDNA FLJ60496; Protein ITFG3; Uncharacterized protein; cDNA FLJ60496 | Solute carrier family 43 member 3; Putative transporter; Belongs to the SLC43A transporter (TC 2.A.1.44) family | 0.475 |
ITFG3 | SLC43A3 | ENSP00000382814 | ENSP00000434515 | Protein FAM234A; Integrin alpha FG-GAP repeat containing 3; Belongs to the FAM234 family | Solute carrier family 43 member 3; Putative transporter; Belongs to the SLC43A transporter (TC 2.A.1.44) family | 0.470 |
NUP160 | SLC43A3 | ENSP00000367721 | ENSP00000434515 | Nuclear pore complex protein Nup160; Involved in poly(A)+ RNA transport; Nucleoporins | Solute carrier family 43 member 3; Putative transporter; Belongs to the SLC43A transporter (TC 2.A.1.44) family | 0.473 |
SLC29A2 | SLC43A3 | ENSP00000350024 | ENSP00000434515 | Equilibrative nucleoside transporter 2; Mediates equilibrative transport of purine, pyrimidine nucleosides and the purine base hypoxanthine. Very less sensitive than SLC29A1 to inhibition by nitrobenzylthioinosine (NBMPR), dipyridamole, dilazep and draflazine; Belongs to the SLC29A/ENT transporter (TC 2.A.57) family | Solute carrier family 43 member 3; Putative transporter; Belongs to the SLC43A transporter (TC 2.A.1.44) family | 0.431 |
SLC38A7 | SLC43A3 | ENSP00000454646 | ENSP00000434515 | Putative sodium-coupled neutral amino acid transporter 7; Mediates sodium-dependent transport of amino acids, preferentially L-glutamine; Belongs to the amino acid/polyamine transporter 2 family | Solute carrier family 43 member 3; Putative transporter; Belongs to the SLC43A transporter (TC 2.A.1.44) family | 0.439 |
SLC43A3 | AQP3 | ENSP00000434515 | ENSP00000297991 | Solute carrier family 43 member 3; Putative transporter; Belongs to the SLC43A transporter (TC 2.A.1.44) family | Aquaporin-3; Water channel required to promote glycerol permeability and water transport across cell membranes. Acts as a glycerol transporter in skin and plays an important role in regulating SC (stratum corneum) and epidermal glycerol content. Involved in skin hydration, wound healing, and tumorigenesis. Provides kidney medullary collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Slightly permeable to urea and may function as a water and urea exit mechanism in antidiuresis in collecting duct cells. It may play an [...] | 0.433 |
SLC43A3 | CSGALNACT2 | ENSP00000434515 | ENSP00000363590 | Solute carrier family 43 member 3; Putative transporter; Belongs to the SLC43A transporter (TC 2.A.1.44) family | Chondroitin sulfate N-acetylgalactosaminyltransferase 2; Transfers 1,4-N-acetylgalactosamine (GalNAc) from UDP- GalNAc to the non-reducing end of glucuronic acid (GlcUA). Required for addition of the first GalNAc to the core tetrasaccharide linker and for elongation of chondroitin chains | 0.471 |
SLC43A3 | ECT2L | ENSP00000434515 | ENSP00000442307 | Solute carrier family 43 member 3; Putative transporter; Belongs to the SLC43A transporter (TC 2.A.1.44) family | Epithelial cell-transforming sequence 2 oncogene-like; May act as a guanine nucleotide exchange factor (GEF); F-boxes other | 0.521 |
SLC43A3 | ENSG00000269881 | ENSP00000434515 | ENSP00000471331 | Solute carrier family 43 member 3; Putative transporter; Belongs to the SLC43A transporter (TC 2.A.1.44) family | cDNA FLJ60496; Protein ITFG3; Uncharacterized protein; cDNA FLJ60496 | 0.475 |
SLC43A3 | ITFG3 | ENSP00000434515 | ENSP00000382814 | Solute carrier family 43 member 3; Putative transporter; Belongs to the SLC43A transporter (TC 2.A.1.44) family | Protein FAM234A; Integrin alpha FG-GAP repeat containing 3; Belongs to the FAM234 family | 0.470 |
SLC43A3 | NUP160 | ENSP00000434515 | ENSP00000367721 | Solute carrier family 43 member 3; Putative transporter; Belongs to the SLC43A transporter (TC 2.A.1.44) family | Nuclear pore complex protein Nup160; Involved in poly(A)+ RNA transport; Nucleoporins | 0.473 |
SLC43A3 | SLC29A2 | ENSP00000434515 | ENSP00000350024 | Solute carrier family 43 member 3; Putative transporter; Belongs to the SLC43A transporter (TC 2.A.1.44) family | Equilibrative nucleoside transporter 2; Mediates equilibrative transport of purine, pyrimidine nucleosides and the purine base hypoxanthine. Very less sensitive than SLC29A1 to inhibition by nitrobenzylthioinosine (NBMPR), dipyridamole, dilazep and draflazine; Belongs to the SLC29A/ENT transporter (TC 2.A.57) family | 0.431 |
SLC43A3 | SLC38A7 | ENSP00000434515 | ENSP00000454646 | Solute carrier family 43 member 3; Putative transporter; Belongs to the SLC43A transporter (TC 2.A.1.44) family | Putative sodium-coupled neutral amino acid transporter 7; Mediates sodium-dependent transport of amino acids, preferentially L-glutamine; Belongs to the amino acid/polyamine transporter 2 family | 0.439 |
SLC43A3 | SLC6A15 | ENSP00000434515 | ENSP00000266682 | Solute carrier family 43 member 3; Putative transporter; Belongs to the SLC43A transporter (TC 2.A.1.44) family | Sodium-dependent neutral amino acid transporter B(0)AT2; Functions as a sodium-dependent neutral amino acid transporter. Exhibits preference for the branched-chain amino acids, particularly leucine, valine and isoleucine and methionine. Mediates the saturable, pH-sensitive and electrogenic cotransport of proline and sodium ions with a stoichiometry of 1-1. May have a role as transporter for neurotransmitter precursors into neurons. In contrast to other members of the neurotransmitter transporter family, does not appear to be chloride-dependent; Solute carriers | 0.541 |
SLC43A3 | ZNF493 | ENSP00000434515 | ENSP00000376110 | Solute carrier family 43 member 3; Putative transporter; Belongs to the SLC43A transporter (TC 2.A.1.44) family | Zinc finger protein 493; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.559 |
SLC6A15 | AQP3 | ENSP00000266682 | ENSP00000297991 | Sodium-dependent neutral amino acid transporter B(0)AT2; Functions as a sodium-dependent neutral amino acid transporter. Exhibits preference for the branched-chain amino acids, particularly leucine, valine and isoleucine and methionine. Mediates the saturable, pH-sensitive and electrogenic cotransport of proline and sodium ions with a stoichiometry of 1-1. May have a role as transporter for neurotransmitter precursors into neurons. In contrast to other members of the neurotransmitter transporter family, does not appear to be chloride-dependent; Solute carriers | Aquaporin-3; Water channel required to promote glycerol permeability and water transport across cell membranes. Acts as a glycerol transporter in skin and plays an important role in regulating SC (stratum corneum) and epidermal glycerol content. Involved in skin hydration, wound healing, and tumorigenesis. Provides kidney medullary collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Slightly permeable to urea and may function as a water and urea exit mechanism in antidiuresis in collecting duct cells. It may play an [...] | 0.446 |