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  • 11.0 [archived version]
STRINGSTRING
ENSG00000274933 ENSG00000274933 CYP1A1 CYP1A1 C10orf113 C10orf113 ENSG00000271449 ENSG00000271449 CT45-2 CT45-2 TMPRSS13 TMPRSS13 ZDHHC24 ZDHHC24 SPINT1 SPINT1 SPINT2 SPINT2 SLC39A2 SLC39A2 HAS1 HAS1
"TMPRSS13" - Transmembrane protease serine 13 in Homo sapiens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
TMPRSS13Transmembrane protease serine 13; Scavenger receptor cysteine rich domain containing; Belongs to the peptidase S1 family (567 aa)    
Predicted Functional Partners:
SPINT2
Kunitz-type protease inhibitor 2; Inhibitor of HGF activator. Also inhibits plasmin, plasma and tissue kallikrein, and factor XIa (252 aa)
      
 
  0.692
SPINT1
Kunitz-type protease inhibitor 1; Inhibitor of HGF activator. Also acts as an inhibitor of matriptase (ST14) (529 aa)
      
 
  0.637
CYP1A1
Cytochrome P450 1A1; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics (512 aa)
        
 
  0.482
HAS1
Hyaluronan synthase 1; Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer. Therefore, it is essential to hyaluronan synthesis a major component of most extracellular matrices that has a structural role in tissues architectures and regulates cell adhesion, migration and differentiation. This is one of the isozymes catalyzing that reaction. Also able to catalyze the synthesis of chito- oligosaccharide depending on the substrate (By similarity); Glycosyltransferase family 2 (578 aa)
            
  0.481
ZDHHC24
Probable palmitoyltransferase ZDHHC24; Zinc finger DHHC-type containing 24; Belongs to the DHHC palmitoyltransferase family (284 aa)
            
  0.474
C10orf113
Putative uncharacterized protein C10orf113; Chromosome 10 open reading frame 113 (155 aa)
            
  0.471
SLC39A2
Zinc transporter ZIP2; Mediates zinc uptake. Zinc uptake may be mediated by a Zn(2+)-HCO(3)(-) symport mechanism and can function in the presence of albumin. May also transport other divalent cations. May be important in contact inhibition of normal epithelial cells and loss of its expression may play a role in tumorigenesis; Solute carriers (309 aa)
      
   
  0.441
ENSG00000274933
TBC1 domain family member 3I; Acts as a GTPase activating protein for RAB5. Does not act on RAB4 or RAB11 (By similarity) (549 aa)
            
  0.440
CT45-2
Cancer/testis antigen family 45 member A2 (189 aa)
            
  0.436
ENSG00000271449
Cancer/testis antigen family 45 member A2 (189 aa)
            
  0.436
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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