| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACSBG2 | NOL8 | ENSP00000465589 | ENSP00000441140 | Long-chain-fatty-acid--CoA ligase ACSBG2; Mediates activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Able to activate long-chain fatty acids. Also able to activate very long-chain fatty acids; however, the relevance of such activity is unclear in vivo. Has increased ability to activate oleic and linoleic acid. May play a role in spermatogenesis; Belongs to the ATP-dependent AMP-binding enzyme family. Bubblegum subfamily | Nucleolar protein 8; Plays an essential role in the survival of diffuse-type gastric cancer cells. Acts as a nucleolar anchoring protein for DDX47. May be involved in regulation of gene expression at the post-transcriptional level or in ribosome biogenesis in cancer cells; RNA binding motif containing | 0.523 |
| ACSBG2 | ZNF585B | ENSP00000465589 | ENSP00000433773 | Long-chain-fatty-acid--CoA ligase ACSBG2; Mediates activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Able to activate long-chain fatty acids. Also able to activate very long-chain fatty acids; however, the relevance of such activity is unclear in vivo. Has increased ability to activate oleic and linoleic acid. May play a role in spermatogenesis; Belongs to the ATP-dependent AMP-binding enzyme family. Bubblegum subfamily | Zinc finger protein 585B; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.436 |
| CNIH2 | OR4D6 | ENSP00000310003 | ENSP00000300127 | Protein cornichon homolog 2; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by regulating their rates of activation, deactivation and desensitization. Blocks CACNG8-mediated resensitization of AMPA receptors; Belongs to the cornichon family | Olfactory receptor 4D6; Odorant receptor; Olfactory receptors, family 4 | 0.444 |
| CNIH2 | ZNF585B | ENSP00000310003 | ENSP00000433773 | Protein cornichon homolog 2; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by regulating their rates of activation, deactivation and desensitization. Blocks CACNG8-mediated resensitization of AMPA receptors; Belongs to the cornichon family | Zinc finger protein 585B; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.420 |
| EIF3L | OR4D6 | ENSP00000485663 | ENSP00000300127 | Eukaryotic translation initiation factor 3 subunit L; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2-GTP-methionyl-tRNAi and eIF-5 to form the 43S pre- initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] | Olfactory receptor 4D6; Odorant receptor; Olfactory receptors, family 4 | 0.497 |
| EIF3L | ZNF585B | ENSP00000485663 | ENSP00000433773 | Eukaryotic translation initiation factor 3 subunit L; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2-GTP-methionyl-tRNAi and eIF-5 to form the 43S pre- initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] | Zinc finger protein 585B; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.402 |
| LHFPL3 | OR4D6 | ENSP00000393128 | ENSP00000300127 | LHFPL tetraspan subfamily member 3 | Olfactory receptor 4D6; Odorant receptor; Olfactory receptors, family 4 | 0.450 |
| LHFPL3 | SCP2D1 | ENSP00000393128 | ENSP00000366645 | LHFPL tetraspan subfamily member 3 | SCP2 sterol-binding domain-containing protein 1; SCP2 sterol binding domain containing 1 | 0.673 |
| LHFPL3 | ZNF585B | ENSP00000393128 | ENSP00000433773 | LHFPL tetraspan subfamily member 3 | Zinc finger protein 585B; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.475 |
| NOL8 | ACSBG2 | ENSP00000441140 | ENSP00000465589 | Nucleolar protein 8; Plays an essential role in the survival of diffuse-type gastric cancer cells. Acts as a nucleolar anchoring protein for DDX47. May be involved in regulation of gene expression at the post-transcriptional level or in ribosome biogenesis in cancer cells; RNA binding motif containing | Long-chain-fatty-acid--CoA ligase ACSBG2; Mediates activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Able to activate long-chain fatty acids. Also able to activate very long-chain fatty acids; however, the relevance of such activity is unclear in vivo. Has increased ability to activate oleic and linoleic acid. May play a role in spermatogenesis; Belongs to the ATP-dependent AMP-binding enzyme family. Bubblegum subfamily | 0.523 |
| NOL8 | ZNF585B | ENSP00000441140 | ENSP00000433773 | Nucleolar protein 8; Plays an essential role in the survival of diffuse-type gastric cancer cells. Acts as a nucleolar anchoring protein for DDX47. May be involved in regulation of gene expression at the post-transcriptional level or in ribosome biogenesis in cancer cells; RNA binding motif containing | Zinc finger protein 585B; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.474 |
| OR4D6 | CNIH2 | ENSP00000300127 | ENSP00000310003 | Olfactory receptor 4D6; Odorant receptor; Olfactory receptors, family 4 | Protein cornichon homolog 2; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by regulating their rates of activation, deactivation and desensitization. Blocks CACNG8-mediated resensitization of AMPA receptors; Belongs to the cornichon family | 0.444 |
| OR4D6 | EIF3L | ENSP00000300127 | ENSP00000485663 | Olfactory receptor 4D6; Odorant receptor; Olfactory receptors, family 4 | Eukaryotic translation initiation factor 3 subunit L; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2-GTP-methionyl-tRNAi and eIF-5 to form the 43S pre- initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] | 0.497 |
| OR4D6 | LHFPL3 | ENSP00000300127 | ENSP00000393128 | Olfactory receptor 4D6; Odorant receptor; Olfactory receptors, family 4 | LHFPL tetraspan subfamily member 3 | 0.450 |
| OR4D6 | ZNF585B | ENSP00000300127 | ENSP00000433773 | Olfactory receptor 4D6; Odorant receptor; Olfactory receptors, family 4 | Zinc finger protein 585B; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.589 |
| SCP2D1 | LHFPL3 | ENSP00000366645 | ENSP00000393128 | SCP2 sterol-binding domain-containing protein 1; SCP2 sterol binding domain containing 1 | LHFPL tetraspan subfamily member 3 | 0.673 |
| SCP2D1 | ZNF585B | ENSP00000366645 | ENSP00000433773 | SCP2 sterol-binding domain-containing protein 1; SCP2 sterol binding domain containing 1 | Zinc finger protein 585B; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.426 |
| TRIM28 | ZNF585B | ENSP00000253024 | ENSP00000433773 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at ’Lys-9’ (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 ’Lys-9 and ’Lys-14’ acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger protein 585B; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.924 |
| ZNF277 | ZNF585B | ENSP00000354501 | ENSP00000433773 | Zinc finger protein 277; May be involved in transcriptional regulation | Zinc finger protein 585B; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.424 |
| ZNF585B | ACSBG2 | ENSP00000433773 | ENSP00000465589 | Zinc finger protein 585B; May be involved in transcriptional regulation; Zinc fingers C2H2-type | Long-chain-fatty-acid--CoA ligase ACSBG2; Mediates activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Able to activate long-chain fatty acids. Also able to activate very long-chain fatty acids; however, the relevance of such activity is unclear in vivo. Has increased ability to activate oleic and linoleic acid. May play a role in spermatogenesis; Belongs to the ATP-dependent AMP-binding enzyme family. Bubblegum subfamily | 0.436 |
