TMEM41B protein (human) - STRING database

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TMEM41B

Transmembrane protein 41B; Required for normal motor neuron development (291 aa)

Predicted Functional Partners:

CHODL

0.625

C19orf54

0.621

ZNF789

0.593

PGAP2

0.560

KLHDC4

0.536

TMEM261

0.532

ARMC7

0.531

LPCAT3

0.528

SETMAR

0.525

EIF3A

0.510

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARMC7	KLHDC4	ENSP00000245543	ENSP00000270583	Armadillo repeat containing 7	Kelch domain containing 4	0.603
ARMC7	TMEM261	ENSP00000245543	ENSP00000350961	Armadillo repeat containing 7	Distal membrane-arm assembly complex protein 1; Required for the assembly of the mitochondrial NADH-ubiquinone oxidoreductase complex (complex I). Involved in the assembly of the distal region of complex I	0.620
ARMC7	TMEM41B	ENSP00000245543	ENSP00000433126	Armadillo repeat containing 7	Transmembrane protein 41B; Required for normal motor neuron development	0.531
C19orf54	TMEM41B	ENSP00000367564	ENSP00000433126	UPF0692 protein C19orf54; Chromosome 19 open reading frame 54; Belongs to the UPF0692 family	Transmembrane protein 41B; Required for normal motor neuron development	0.621
CHODL	TMEM41B	ENSP00000299295	ENSP00000433126	Chondrolectin; May play a role in the development of the nervous system such as in neurite outgrowth and elongation. May be involved in motor axon growth and guidance; C-type lectin domain containing	Transmembrane protein 41B; Required for normal motor neuron development	0.625
EIF3A	TMEM41B	ENSP00000358140	ENSP00000433126	Eukaryotic translation initiation factor 3 subunit A; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2-GTP-methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termi [...]	Transmembrane protein 41B; Required for normal motor neuron development	0.510
KLHDC4	ARMC7	ENSP00000270583	ENSP00000245543	Kelch domain containing 4	Armadillo repeat containing 7	0.603
KLHDC4	TMEM261	ENSP00000270583	ENSP00000350961	Kelch domain containing 4	Distal membrane-arm assembly complex protein 1; Required for the assembly of the mitochondrial NADH-ubiquinone oxidoreductase complex (complex I). Involved in the assembly of the distal region of complex I	0.609
KLHDC4	TMEM41B	ENSP00000270583	ENSP00000433126	Kelch domain containing 4	Transmembrane protein 41B; Required for normal motor neuron development	0.536
LPCAT3	PGAP2	ENSP00000261407	ENSP00000278243	Lysophospholipid acyltransferase 5; Acyltransferase which mediates the conversion of lysophosphatidylcholine (1-acyl-sn-glycero-3-phosphocholine or LPC) into phosphatidylcholine (1,2-diacyl-sn-glycero-3- phosphocholine or PC) (LPCAT activity). Catalyzes also the conversion of lysophosphatidylserine (1-acyl-2-hydroxy-sn-glycero- 3-phospho-L-serine or LPS) into phosphatidylserine (1,2-diacyl-sn- glycero-3-phospho-L-serine or PS) (LPSAT activity). Has also weak lysophosphatidylethanolamine acyltransferase activity (LPEAT activity). Favors polyunsaturated fatty acyl-CoAs as acyl donors com [...]	Post-GPI attachment to proteins factor 2; Involved in the lipid remodeling steps of GPI-anchor maturation. Required for stable expression of GPI-anchored proteins at the cell surface (By similarity)	0.501
LPCAT3	TMEM41B	ENSP00000261407	ENSP00000433126	Lysophospholipid acyltransferase 5; Acyltransferase which mediates the conversion of lysophosphatidylcholine (1-acyl-sn-glycero-3-phosphocholine or LPC) into phosphatidylcholine (1,2-diacyl-sn-glycero-3- phosphocholine or PC) (LPCAT activity). Catalyzes also the conversion of lysophosphatidylserine (1-acyl-2-hydroxy-sn-glycero- 3-phospho-L-serine or LPS) into phosphatidylserine (1,2-diacyl-sn- glycero-3-phospho-L-serine or PS) (LPSAT activity). Has also weak lysophosphatidylethanolamine acyltransferase activity (LPEAT activity). Favors polyunsaturated fatty acyl-CoAs as acyl donors com [...]	Transmembrane protein 41B; Required for normal motor neuron development	0.528
PGAP2	LPCAT3	ENSP00000278243	ENSP00000261407	Post-GPI attachment to proteins factor 2; Involved in the lipid remodeling steps of GPI-anchor maturation. Required for stable expression of GPI-anchored proteins at the cell surface (By similarity)	Lysophospholipid acyltransferase 5; Acyltransferase which mediates the conversion of lysophosphatidylcholine (1-acyl-sn-glycero-3-phosphocholine or LPC) into phosphatidylcholine (1,2-diacyl-sn-glycero-3- phosphocholine or PC) (LPCAT activity). Catalyzes also the conversion of lysophosphatidylserine (1-acyl-2-hydroxy-sn-glycero- 3-phospho-L-serine or LPS) into phosphatidylserine (1,2-diacyl-sn- glycero-3-phospho-L-serine or PS) (LPSAT activity). Has also weak lysophosphatidylethanolamine acyltransferase activity (LPEAT activity). Favors polyunsaturated fatty acyl-CoAs as acyl donors com [...]	0.501
PGAP2	TMEM41B	ENSP00000278243	ENSP00000433126	Post-GPI attachment to proteins factor 2; Involved in the lipid remodeling steps of GPI-anchor maturation. Required for stable expression of GPI-anchored proteins at the cell surface (By similarity)	Transmembrane protein 41B; Required for normal motor neuron development	0.560
SETMAR	TMEM41B	ENSP00000373354	ENSP00000433126	Histone-lysine N-methyltransferase SETMAR; Protein derived from the fusion of a methylase with the transposase of an Hsmar1 transposon that plays a role in DNA double-strand break repair, stalled replication fork restart and DNA integration. DNA-binding protein, it is indirectly recruited to sites of DNA damage through protein-protein interactions. Has also kept a sequence-specific DNA-binding activity recognizing the 19-mer core of the 5’-terminal inverted repeats (TIRs) of the Hsmar1 element and displays a DNA nicking and end joining activity. In parallel, has a histone methyltransfe [...]	Transmembrane protein 41B; Required for normal motor neuron development	0.525
TMEM261	ARMC7	ENSP00000350961	ENSP00000245543	Distal membrane-arm assembly complex protein 1; Required for the assembly of the mitochondrial NADH-ubiquinone oxidoreductase complex (complex I). Involved in the assembly of the distal region of complex I	Armadillo repeat containing 7	0.620
TMEM261	KLHDC4	ENSP00000350961	ENSP00000270583	Distal membrane-arm assembly complex protein 1; Required for the assembly of the mitochondrial NADH-ubiquinone oxidoreductase complex (complex I). Involved in the assembly of the distal region of complex I	Kelch domain containing 4	0.609
TMEM261	TMEM41B	ENSP00000350961	ENSP00000433126	Distal membrane-arm assembly complex protein 1; Required for the assembly of the mitochondrial NADH-ubiquinone oxidoreductase complex (complex I). Involved in the assembly of the distal region of complex I	Transmembrane protein 41B; Required for normal motor neuron development	0.532
TMEM41B	ARMC7	ENSP00000433126	ENSP00000245543	Transmembrane protein 41B; Required for normal motor neuron development	Armadillo repeat containing 7	0.531
TMEM41B	C19orf54	ENSP00000433126	ENSP00000367564	Transmembrane protein 41B; Required for normal motor neuron development	UPF0692 protein C19orf54; Chromosome 19 open reading frame 54; Belongs to the UPF0692 family	0.621
TMEM41B	CHODL	ENSP00000433126	ENSP00000299295	Transmembrane protein 41B; Required for normal motor neuron development	Chondrolectin; May play a role in the development of the nervous system such as in neurite outgrowth and elongation. May be involved in motor axon growth and guidance; C-type lectin domain containing	0.625

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