node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AP1S1 | EBLN2 | ENSP00000336666 | ENSP00000432104 | AP-1 complex subunit sigma-1A; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules | Endogenous Bornavirus-like nucleoprotein 2; May act as an RNA-binding protein. The C-terminal region is highly homologous to the bornavirus nucleocapsid N protein that binds viral RNA and oligomerizes. The viral protein also possesses a nuclear import and a nuclear export signal. These 2 signals seem absent in EBLN-2 supporting an unrelated function in Human | 0.607 |
AP1S1 | TUSC2 | ENSP00000336666 | ENSP00000232496 | AP-1 complex subunit sigma-1A; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules | Tumor suppressor candidate 2; May function as a tumor suppressor, inhibiting colony formation, causing G1 arrest and ultimately inducing apoptosis in homozygous 3p21.3 120-kb region-deficient cells; Belongs to the TUSC2 family | 0.679 |
EBLN2 | AP1S1 | ENSP00000432104 | ENSP00000336666 | Endogenous Bornavirus-like nucleoprotein 2; May act as an RNA-binding protein. The C-terminal region is highly homologous to the bornavirus nucleocapsid N protein that binds viral RNA and oligomerizes. The viral protein also possesses a nuclear import and a nuclear export signal. These 2 signals seem absent in EBLN-2 supporting an unrelated function in Human | AP-1 complex subunit sigma-1A; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules | 0.607 |
EBLN2 | GON4L | ENSP00000432104 | ENSP00000357315 | Endogenous Bornavirus-like nucleoprotein 2; May act as an RNA-binding protein. The C-terminal region is highly homologous to the bornavirus nucleocapsid N protein that binds viral RNA and oligomerizes. The viral protein also possesses a nuclear import and a nuclear export signal. These 2 signals seem absent in EBLN-2 supporting an unrelated function in Human | GON-4-like protein; Has transcriptional repressor activity, probably as part of a complex with YY1, SIN3A AND HDAC1. Required for B cell lymphopoiesis; Myb/SANT domain containing | 0.474 |
EBLN2 | KIAA2018 | ENSP00000432104 | ENSP00000320794 | Endogenous Bornavirus-like nucleoprotein 2; May act as an RNA-binding protein. The C-terminal region is highly homologous to the bornavirus nucleocapsid N protein that binds viral RNA and oligomerizes. The viral protein also possesses a nuclear import and a nuclear export signal. These 2 signals seem absent in EBLN-2 supporting an unrelated function in Human | Basic helix-loop-helix domain-containing protein USF3; Involved in the negative regulation of epithelial- mesenchymal transition, the process by which epithelial cells lose their polarity and adhesion properties to become mesenchymal cells with enhanced migration and invasive properties | 0.520 |
EBLN2 | LIME1 | ENSP00000432104 | ENSP00000309521 | Endogenous Bornavirus-like nucleoprotein 2; May act as an RNA-binding protein. The C-terminal region is highly homologous to the bornavirus nucleocapsid N protein that binds viral RNA and oligomerizes. The viral protein also possesses a nuclear import and a nuclear export signal. These 2 signals seem absent in EBLN-2 supporting an unrelated function in Human | Lck-interacting transmembrane adapter 1; Involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and TCR (T-cell antigen receptor)-mediated T- cell signaling in T-cells. In absence of TCR signaling, may be involved in CD4-mediated inhibition of T-cell activation. Couples activation of these receptors and their associated kinases with distal intracellular events such as calcium mobilization or MAPK activation through the recruitment of PLCG2, GRB2, GRAP2, and other signaling molecules | 0.473 |
EBLN2 | OR4F6 | ENSP00000432104 | ENSP00000327525 | Endogenous Bornavirus-like nucleoprotein 2; May act as an RNA-binding protein. The C-terminal region is highly homologous to the bornavirus nucleocapsid N protein that binds viral RNA and oligomerizes. The viral protein also possesses a nuclear import and a nuclear export signal. These 2 signals seem absent in EBLN-2 supporting an unrelated function in Human | Olfactory receptor 4F6; Odorant receptor; Olfactory receptors, family 4 | 0.670 |
EBLN2 | SPATC1L | ENSP00000432104 | ENSP00000291672 | Endogenous Bornavirus-like nucleoprotein 2; May act as an RNA-binding protein. The C-terminal region is highly homologous to the bornavirus nucleocapsid N protein that binds viral RNA and oligomerizes. The viral protein also possesses a nuclear import and a nuclear export signal. These 2 signals seem absent in EBLN-2 supporting an unrelated function in Human | Speriolin-like protein; Spermatogenesis and centriole associated 1 like | 0.526 |
EBLN2 | TCEB3C | ENSP00000432104 | ENSP00000328232 | Endogenous Bornavirus-like nucleoprotein 2; May act as an RNA-binding protein. The C-terminal region is highly homologous to the bornavirus nucleocapsid N protein that binds viral RNA and oligomerizes. The viral protein also possesses a nuclear import and a nuclear export signal. These 2 signals seem absent in EBLN-2 supporting an unrelated function in Human | Elongin-A3; SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A3 is transcriptionally active but its transcription activity is not enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex) | 0.516 |
EBLN2 | TUSC2 | ENSP00000432104 | ENSP00000232496 | Endogenous Bornavirus-like nucleoprotein 2; May act as an RNA-binding protein. The C-terminal region is highly homologous to the bornavirus nucleocapsid N protein that binds viral RNA and oligomerizes. The viral protein also possesses a nuclear import and a nuclear export signal. These 2 signals seem absent in EBLN-2 supporting an unrelated function in Human | Tumor suppressor candidate 2; May function as a tumor suppressor, inhibiting colony formation, causing G1 arrest and ultimately inducing apoptosis in homozygous 3p21.3 120-kb region-deficient cells; Belongs to the TUSC2 family | 0.710 |
EBLN2 | ZNF229 | ENSP00000432104 | ENSP00000479884 | Endogenous Bornavirus-like nucleoprotein 2; May act as an RNA-binding protein. The C-terminal region is highly homologous to the bornavirus nucleocapsid N protein that binds viral RNA and oligomerizes. The viral protein also possesses a nuclear import and a nuclear export signal. These 2 signals seem absent in EBLN-2 supporting an unrelated function in Human | Zinc finger protein 229; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.642 |
EBLN2 | ZNF311 | ENSP00000432104 | ENSP00000366384 | Endogenous Bornavirus-like nucleoprotein 2; May act as an RNA-binding protein. The C-terminal region is highly homologous to the bornavirus nucleocapsid N protein that binds viral RNA and oligomerizes. The viral protein also possesses a nuclear import and a nuclear export signal. These 2 signals seem absent in EBLN-2 supporting an unrelated function in Human | Zinc finger protein 311; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.556 |
GON4L | EBLN2 | ENSP00000357315 | ENSP00000432104 | GON-4-like protein; Has transcriptional repressor activity, probably as part of a complex with YY1, SIN3A AND HDAC1. Required for B cell lymphopoiesis; Myb/SANT domain containing | Endogenous Bornavirus-like nucleoprotein 2; May act as an RNA-binding protein. The C-terminal region is highly homologous to the bornavirus nucleocapsid N protein that binds viral RNA and oligomerizes. The viral protein also possesses a nuclear import and a nuclear export signal. These 2 signals seem absent in EBLN-2 supporting an unrelated function in Human | 0.474 |
GON4L | ZNF311 | ENSP00000357315 | ENSP00000366384 | GON-4-like protein; Has transcriptional repressor activity, probably as part of a complex with YY1, SIN3A AND HDAC1. Required for B cell lymphopoiesis; Myb/SANT domain containing | Zinc finger protein 311; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.414 |
KIAA2018 | EBLN2 | ENSP00000320794 | ENSP00000432104 | Basic helix-loop-helix domain-containing protein USF3; Involved in the negative regulation of epithelial- mesenchymal transition, the process by which epithelial cells lose their polarity and adhesion properties to become mesenchymal cells with enhanced migration and invasive properties | Endogenous Bornavirus-like nucleoprotein 2; May act as an RNA-binding protein. The C-terminal region is highly homologous to the bornavirus nucleocapsid N protein that binds viral RNA and oligomerizes. The viral protein also possesses a nuclear import and a nuclear export signal. These 2 signals seem absent in EBLN-2 supporting an unrelated function in Human | 0.520 |
KIAA2018 | ZNF311 | ENSP00000320794 | ENSP00000366384 | Basic helix-loop-helix domain-containing protein USF3; Involved in the negative regulation of epithelial- mesenchymal transition, the process by which epithelial cells lose their polarity and adhesion properties to become mesenchymal cells with enhanced migration and invasive properties | Zinc finger protein 311; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.440 |
LIME1 | EBLN2 | ENSP00000309521 | ENSP00000432104 | Lck-interacting transmembrane adapter 1; Involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and TCR (T-cell antigen receptor)-mediated T- cell signaling in T-cells. In absence of TCR signaling, may be involved in CD4-mediated inhibition of T-cell activation. Couples activation of these receptors and their associated kinases with distal intracellular events such as calcium mobilization or MAPK activation through the recruitment of PLCG2, GRB2, GRAP2, and other signaling molecules | Endogenous Bornavirus-like nucleoprotein 2; May act as an RNA-binding protein. The C-terminal region is highly homologous to the bornavirus nucleocapsid N protein that binds viral RNA and oligomerizes. The viral protein also possesses a nuclear import and a nuclear export signal. These 2 signals seem absent in EBLN-2 supporting an unrelated function in Human | 0.473 |
OR4F6 | EBLN2 | ENSP00000327525 | ENSP00000432104 | Olfactory receptor 4F6; Odorant receptor; Olfactory receptors, family 4 | Endogenous Bornavirus-like nucleoprotein 2; May act as an RNA-binding protein. The C-terminal region is highly homologous to the bornavirus nucleocapsid N protein that binds viral RNA and oligomerizes. The viral protein also possesses a nuclear import and a nuclear export signal. These 2 signals seem absent in EBLN-2 supporting an unrelated function in Human | 0.670 |
OR4F6 | ZNF229 | ENSP00000327525 | ENSP00000479884 | Olfactory receptor 4F6; Odorant receptor; Olfactory receptors, family 4 | Zinc finger protein 229; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.671 |
SPATC1L | EBLN2 | ENSP00000291672 | ENSP00000432104 | Speriolin-like protein; Spermatogenesis and centriole associated 1 like | Endogenous Bornavirus-like nucleoprotein 2; May act as an RNA-binding protein. The C-terminal region is highly homologous to the bornavirus nucleocapsid N protein that binds viral RNA and oligomerizes. The viral protein also possesses a nuclear import and a nuclear export signal. These 2 signals seem absent in EBLN-2 supporting an unrelated function in Human | 0.526 |