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  • 11.0 [archived version]
STRINGSTRING
ZMYM2 ZMYM2 ZMYM3 ZMYM3 EFCAB2 EFCAB2 GIN1 GIN1 PGBD5 PGBD5 HARBI1 HARBI1 QRICH1 QRICH1 THAP9 THAP9 ZBED8 ZBED8 SETMAR SETMAR PGBD2 PGBD2
"PGBD5" - PiggyBac transposable element-derived protein 5 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PGBD5PiggyBac transposable element-derived protein 5; Transposase that mediates sequence-specific genomic rearrangements. Can induce genomic rearrangements that inactivate the HPRT1 gene; DNA transposon derived genes (455 aa)    
Predicted Functional Partners:
THAP9
DNA transposase THAP9; Active transposase that specifically recognizes the bipartite 5’-TXXGGGX(A/T)-3’ consensus motif and mediates transposition; THAP domain containing (903 aa)
            
  0.854
HARBI1
Putative nuclease HARBI1; Transposase-derived protein that may have nuclease activity (Potential). Does not have transposase activity; DNA transposon derived genes (349 aa)
            
  0.795
QRICH1
Glutamine-rich protein 1; Glutamine rich 1 (776 aa)
            
  0.791
EFCAB2
EF-hand calcium-binding domain-containing protein 2; EF-hand calcium binding domain 2; Cilia and flagella associated (162 aa)
            
  0.770
PGBD2
piggyBac transposable element derived 2; DNA transposon derived genes (592 aa)
            
  0.762
GIN1
Gypsy retrotransposon integrase 1 (522 aa)
            
  0.749
ZBED8
Protein ZBED8; Zinc finger BED-type containing 8 (594 aa)
            
  0.720
SETMAR
Histone-lysine N-methyltransferase SETMAR; Protein derived from the fusion of a methylase with the transposase of an Hsmar1 transposon that plays a role in DNA double-strand break repair, stalled replication fork restart and DNA integration. DNA-binding protein, it is indirectly recruited to sites of DNA damage through protein-protein interactions. Has also kept a sequence-specific DNA-binding activity recognizing the 19-mer core of the 5’-terminal inverted repeats (TIRs) of the Hsmar1 element and displays a DNA nicking and end joining activity. In parallel, has a histone methyltransfe [...] (684 aa)
            
  0.717
ZMYM3
Zinc finger MYM-type protein 3; Plays a role in the regulation of cell morphology and cytoskeletal organization; Zinc fingers MYM-type (1370 aa)
            
  0.712
ZMYM2
Zinc finger MYM-type protein 2; May function as a transcription factor; Zinc fingers MYM-type (1377 aa)
            
  0.707
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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