node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ATOH8 | ZFP82 | ENSP00000304676 | ENSP00000431265 | Protein atonal homolog 8; Transcription factor that binds a palindromic (canonical) core consensus DNA sequence 5’-CANNTG- 3’ known as an E-box element, possibly as a heterodimer with other bHLH proteins. Regulates endothelial cell proliferation, migration and tube-like structures formation. Modulates endothelial cell differentiation through NOS3. May be implicated in specification and differentiation of neuronal cell lineages in the brain (By similarity). May participate in kidney development and may be involved in podocyte differentiation (By similarity). During early embryonic devel [...] | Zinc finger protein 82 homolog; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.444 |
RERG | SHISA3 | ENSP00000256953 | ENSP00000326445 | Ras-related and estrogen-regulated growth inhibitor; Binds GDP/GTP and possesses intrinsic GTPase activity. Has higher affinity for GDP than for GTP. In cell lines overexpression leads to a reduction in the rate of proliferation, colony formation and in tumorigenic potential; RAS type GTPase family | Protein shisa-3 homolog; Plays an essential role in the maturation of presomitic mesoderm cells by individual attenuation of both FGF and WNT signaling; Shisa family members | 0.487 |
RERG | ZFP82 | ENSP00000256953 | ENSP00000431265 | Ras-related and estrogen-regulated growth inhibitor; Binds GDP/GTP and possesses intrinsic GTPase activity. Has higher affinity for GDP than for GTP. In cell lines overexpression leads to a reduction in the rate of proliferation, colony formation and in tumorigenic potential; RAS type GTPase family | Zinc finger protein 82 homolog; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.527 |
RRAD | ZFP82 | ENSP00000299759 | ENSP00000431265 | GTP-binding protein RAD; May play an important role in cardiac antiarrhythmia via the strong suppression of voltage-gated L-type Ca(2+) currents. Regulates voltage-dependent L-type calcium channel subunit alpha- 1C trafficking to the cell membrane (By similarity). Inhibits cardiac hypertrophy through the calmodulin-dependent kinase II (CaMKII) pathway. Inhibits phosphorylation and activation of CAMK2D; Belongs to the small GTPase superfamily. RGK family | Zinc finger protein 82 homolog; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.437 |
SHISA3 | RERG | ENSP00000326445 | ENSP00000256953 | Protein shisa-3 homolog; Plays an essential role in the maturation of presomitic mesoderm cells by individual attenuation of both FGF and WNT signaling; Shisa family members | Ras-related and estrogen-regulated growth inhibitor; Binds GDP/GTP and possesses intrinsic GTPase activity. Has higher affinity for GDP than for GTP. In cell lines overexpression leads to a reduction in the rate of proliferation, colony formation and in tumorigenic potential; RAS type GTPase family | 0.487 |
SHISA3 | ZFP82 | ENSP00000326445 | ENSP00000431265 | Protein shisa-3 homolog; Plays an essential role in the maturation of presomitic mesoderm cells by individual attenuation of both FGF and WNT signaling; Shisa family members | Zinc finger protein 82 homolog; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.574 |
SHISA3 | ZMYND10 | ENSP00000326445 | ENSP00000231749 | Protein shisa-3 homolog; Plays an essential role in the maturation of presomitic mesoderm cells by individual attenuation of both FGF and WNT signaling; Shisa family members | Zinc finger MYND domain-containing protein 10; Required for motile ciliary function. Probably involved in axonemal assembly of inner and outer dynein arms (IDA and ODA, respectively) for proper axoneme building for cilia motility. May act by indirectly regulating transcription of dynein proteins; Belongs to the ZMYND10 family | 0.411 |
ZBTB25 | ZFP82 | ENSP00000476746 | ENSP00000431265 | Zinc finger and BTB domain-containing protein 25; May be involved in transcriptional regulation; BTB domain containing | Zinc finger protein 82 homolog; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.538 |
ZFP82 | ATOH8 | ENSP00000431265 | ENSP00000304676 | Zinc finger protein 82 homolog; May be involved in transcriptional regulation; Zinc fingers C2H2-type | Protein atonal homolog 8; Transcription factor that binds a palindromic (canonical) core consensus DNA sequence 5’-CANNTG- 3’ known as an E-box element, possibly as a heterodimer with other bHLH proteins. Regulates endothelial cell proliferation, migration and tube-like structures formation. Modulates endothelial cell differentiation through NOS3. May be implicated in specification and differentiation of neuronal cell lineages in the brain (By similarity). May participate in kidney development and may be involved in podocyte differentiation (By similarity). During early embryonic devel [...] | 0.444 |
ZFP82 | RERG | ENSP00000431265 | ENSP00000256953 | Zinc finger protein 82 homolog; May be involved in transcriptional regulation; Zinc fingers C2H2-type | Ras-related and estrogen-regulated growth inhibitor; Binds GDP/GTP and possesses intrinsic GTPase activity. Has higher affinity for GDP than for GTP. In cell lines overexpression leads to a reduction in the rate of proliferation, colony formation and in tumorigenic potential; RAS type GTPase family | 0.527 |
ZFP82 | RRAD | ENSP00000431265 | ENSP00000299759 | Zinc finger protein 82 homolog; May be involved in transcriptional regulation; Zinc fingers C2H2-type | GTP-binding protein RAD; May play an important role in cardiac antiarrhythmia via the strong suppression of voltage-gated L-type Ca(2+) currents. Regulates voltage-dependent L-type calcium channel subunit alpha- 1C trafficking to the cell membrane (By similarity). Inhibits cardiac hypertrophy through the calmodulin-dependent kinase II (CaMKII) pathway. Inhibits phosphorylation and activation of CAMK2D; Belongs to the small GTPase superfamily. RGK family | 0.437 |
ZFP82 | SHISA3 | ENSP00000431265 | ENSP00000326445 | Zinc finger protein 82 homolog; May be involved in transcriptional regulation; Zinc fingers C2H2-type | Protein shisa-3 homolog; Plays an essential role in the maturation of presomitic mesoderm cells by individual attenuation of both FGF and WNT signaling; Shisa family members | 0.574 |
ZFP82 | ZBTB25 | ENSP00000431265 | ENSP00000476746 | Zinc finger protein 82 homolog; May be involved in transcriptional regulation; Zinc fingers C2H2-type | Zinc finger and BTB domain-containing protein 25; May be involved in transcriptional regulation; BTB domain containing | 0.538 |
ZFP82 | ZMYND10 | ENSP00000431265 | ENSP00000231749 | Zinc finger protein 82 homolog; May be involved in transcriptional regulation; Zinc fingers C2H2-type | Zinc finger MYND domain-containing protein 10; Required for motile ciliary function. Probably involved in axonemal assembly of inner and outer dynein arms (IDA and ODA, respectively) for proper axoneme building for cilia motility. May act by indirectly regulating transcription of dynein proteins; Belongs to the ZMYND10 family | 0.486 |
ZMYND10 | SHISA3 | ENSP00000231749 | ENSP00000326445 | Zinc finger MYND domain-containing protein 10; Required for motile ciliary function. Probably involved in axonemal assembly of inner and outer dynein arms (IDA and ODA, respectively) for proper axoneme building for cilia motility. May act by indirectly regulating transcription of dynein proteins; Belongs to the ZMYND10 family | Protein shisa-3 homolog; Plays an essential role in the maturation of presomitic mesoderm cells by individual attenuation of both FGF and WNT signaling; Shisa family members | 0.411 |
ZMYND10 | ZFP82 | ENSP00000231749 | ENSP00000431265 | Zinc finger MYND domain-containing protein 10; Required for motile ciliary function. Probably involved in axonemal assembly of inner and outer dynein arms (IDA and ODA, respectively) for proper axoneme building for cilia motility. May act by indirectly regulating transcription of dynein proteins; Belongs to the ZMYND10 family | Zinc finger protein 82 homolog; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.486 |