• Version:
  • 11.0 [archived version]
STRINGSTRING
ENSG00000256825 ENSG00000256825 FRMD4B FRMD4B CCDC180 CCDC180 FAM92A1 FAM92A1 PTPN20A PTPN20A OGFRL1 OGFRL1 ZNF345 ZNF345 CCDC18 CCDC18 ZNF608 ZNF608 ZNF207 ZNF207 BLZF1 BLZF1
"ZNF345" - Zinc finger protein 345 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZNF345Zinc finger protein 345; May be involved in transcriptional regulation; Zinc fingers C2H2-type (488 aa)    
Predicted Functional Partners:
FAM92A1
Protein FAM92A; May play a role in ciliogenesis. In cooperation with CBY1 may facilitate ciliogenesis likely by the recruitment and fusion of endosomal vesicles at distal appendages during early stages of ciliogenesis (289 aa)
           
  0.549
ZNF608
Zinc finger protein 608; Transcription factor, which represses ZNF609 transcription; Zinc fingers C2H2-type (1512 aa)
           
  0.530
OGFRL1
Opioid growth factor receptor like 1 (451 aa)
           
  0.522
CCDC180
Coiled-coil domain containing 180 (1701 aa)
           
  0.473
PTPN20A
Tyrosine-protein phosphatase non-receptor type 20; Tyrosine-protein phosphatase targeted to sites of actin polymerization in response of varied extracellular stimuli. Has tyrosine phosphatase activity towards various tyrosyl phosphorylated substrates (420 aa)
       
 
  0.451
FRMD4B
FERM domain-containing protein 4B; Member of GRP1 signaling complexes that are acutely recruited to plasma membrane ruffles in response to insulin receptor signaling. May function as a scaffolding protein that regulates epithelial cell polarity by connecting ARF6 activation with the PAR3 complex. Plays a redundant role with FRMD4A in epithelial polarization; FERM domain containing (1034 aa)
           
  0.442
BLZF1
Golgin-45; Required for normal Golgi structure and for protein transport from the endoplasmic reticulum (ER) through the Golgi apparatus to the cell surface (400 aa)
           
  0.428
ENSG00000256825
Zinc finger protein 268 (358 aa)
           
  0.426
CCDC18
Coiled-coil domain containing 18 (1299 aa)
           
  0.422
ZNF207
BUB3-interacting and GLEBS motif-containing protein ZNF207; Kinetochore- and microtubule-binding protein that plays a key role in spindle assembly. ZNF207/BuGZ is mainly composed of disordered low-complexity regions and undergoes phase transition or coacervation to form temperature-dependent liquid droplets. Coacervation promotes microtubule bundling and concentrates tubulin, promoting microtubule polymerization and assembly of spindle and spindle matrix by concentrating its building blocks. Also acts as a regulator of mitotic chromosome alignment by mediating the stability and kinetoc [...] (494 aa)
           
  0.413
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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