CCDC71L protein (human) - STRING database

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CCDC71L

Coiled-coil domain-containing protein 71L; Coiled-coil domain containing 71 like (235 aa)

Predicted Functional Partners:

ZNF280A

0.685

ZNF280B

0.567

TTC39A

0.563

GCSAML

0.539

SLC17A4

0.530

ZNF396

0.530

CDYL

0.526

METTL20

0.496

CLVS1

0.493

MTMR8

0.493

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCDC71L	CDYL	ENSP00000430897	ENSP00000380718	Coiled-coil domain-containing protein 71L; Coiled-coil domain containing 71 like	Chromodomain Y-like protein; Isoform 2- Chromatin reader protein that recognizes and binds histone H3 trimethylated at ’Lys-9’, dimethylated at ’Lys- 27’ and trimethylated at ’Lys-27’ (H3K9me3, H3K27me2 and H3K27me3, respectively). Part of multimeric repressive chromatin complexes, where it is required for transmission and restoration of repressive histone marks, thereby preserving the epigenetic landscape. Required for chromatin targeting and maximal enzymatic activity of Polycomb repressive complex 2 (PRC2); acts as a positive regulator of PRC2 activity by bridging the pre-existing h [...]	0.526
CCDC71L	CLVS1	ENSP00000430897	ENSP00000428402	Coiled-coil domain-containing protein 71L; Coiled-coil domain containing 71 like	Clavesin-1; Required for normal morphology of late endosomes and/or lysosomes in neurons (By similarity). Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2)	0.493
CCDC71L	GCSAML	ENSP00000430897	ENSP00000446460	Coiled-coil domain-containing protein 71L; Coiled-coil domain containing 71 like	Germinal center associated signaling and motility like	0.539
CCDC71L	METTL20	ENSP00000430897	ENSP00000350353	Coiled-coil domain-containing protein 71L; Coiled-coil domain containing 71 like	Electron transfer flavoprotein beta subunit lysine methyltransferase; Protein-lysine methyltransferase that selectively trimethylates the flavoprotein ETFB in mitochondria. Thereby, may negatively regulate the function of ETFB in electron transfer from Acyl-CoA dehydrogenases to the main respiratory chain	0.496
CCDC71L	MTMR8	ENSP00000430897	ENSP00000363985	Coiled-coil domain-containing protein 71L; Coiled-coil domain containing 71 like	Myotubularin-related protein 8; Phosphatase that acts on lipids with a phosphoinositol headgroup; Myotubularins	0.493
CCDC71L	SLC17A4	ENSP00000430897	ENSP00000367137	Coiled-coil domain-containing protein 71L; Coiled-coil domain containing 71 like	Probable small intestine urate exporter; Acts as a membrane potential-dependent organic anion transporter, the transport requires a low concentration of chloride ions. May be involved in urate extrusion from the intestinal duct. May recognize hydrophilic anionic drugs such as aspirin, salicylate, and ibuprofen as substrates. Able to actively transport inorganic phosphate into cells via Na(+) cotransport (in vitro); Belongs to the major facilitator superfamily. Sodium/anion cotransporter family	0.530
CCDC71L	TTC39A	ENSP00000430897	ENSP00000393952	Coiled-coil domain-containing protein 71L; Coiled-coil domain containing 71 like	Tetratricopeptide repeat domain containing	0.563
CCDC71L	ZNF280A	ENSP00000430897	ENSP00000302855	Coiled-coil domain-containing protein 71L; Coiled-coil domain containing 71 like	Zinc finger protein 280A; May function as a transcription factor	0.685
CCDC71L	ZNF280B	ENSP00000430897	ENSP00000480958	Coiled-coil domain-containing protein 71L; Coiled-coil domain containing 71 like	Zinc finger protein 280B; May function as a transcription factor	0.567
CCDC71L	ZNF396	ENSP00000430897	ENSP00000302310	Coiled-coil domain-containing protein 71L; Coiled-coil domain containing 71 like	Zinc finger protein 396; Isoform 1 and isoform 2 act as DNA-dependent transcriptional repressors; Belongs to the krueppel C2H2-type zinc-finger protein family	0.530
CDYL	CCDC71L	ENSP00000380718	ENSP00000430897	Chromodomain Y-like protein; Isoform 2- Chromatin reader protein that recognizes and binds histone H3 trimethylated at ’Lys-9’, dimethylated at ’Lys- 27’ and trimethylated at ’Lys-27’ (H3K9me3, H3K27me2 and H3K27me3, respectively). Part of multimeric repressive chromatin complexes, where it is required for transmission and restoration of repressive histone marks, thereby preserving the epigenetic landscape. Required for chromatin targeting and maximal enzymatic activity of Polycomb repressive complex 2 (PRC2); acts as a positive regulator of PRC2 activity by bridging the pre-existing h [...]	Coiled-coil domain-containing protein 71L; Coiled-coil domain containing 71 like	0.526
CDYL	ZNF280A	ENSP00000380718	ENSP00000302855	Chromodomain Y-like protein; Isoform 2- Chromatin reader protein that recognizes and binds histone H3 trimethylated at ’Lys-9’, dimethylated at ’Lys- 27’ and trimethylated at ’Lys-27’ (H3K9me3, H3K27me2 and H3K27me3, respectively). Part of multimeric repressive chromatin complexes, where it is required for transmission and restoration of repressive histone marks, thereby preserving the epigenetic landscape. Required for chromatin targeting and maximal enzymatic activity of Polycomb repressive complex 2 (PRC2); acts as a positive regulator of PRC2 activity by bridging the pre-existing h [...]	Zinc finger protein 280A; May function as a transcription factor	0.717
CDYL	ZNF280B	ENSP00000380718	ENSP00000480958	Chromodomain Y-like protein; Isoform 2- Chromatin reader protein that recognizes and binds histone H3 trimethylated at ’Lys-9’, dimethylated at ’Lys- 27’ and trimethylated at ’Lys-27’ (H3K9me3, H3K27me2 and H3K27me3, respectively). Part of multimeric repressive chromatin complexes, where it is required for transmission and restoration of repressive histone marks, thereby preserving the epigenetic landscape. Required for chromatin targeting and maximal enzymatic activity of Polycomb repressive complex 2 (PRC2); acts as a positive regulator of PRC2 activity by bridging the pre-existing h [...]	Zinc finger protein 280B; May function as a transcription factor	0.770
CLVS1	CCDC71L	ENSP00000428402	ENSP00000430897	Clavesin-1; Required for normal morphology of late endosomes and/or lysosomes in neurons (By similarity). Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2)	Coiled-coil domain-containing protein 71L; Coiled-coil domain containing 71 like	0.493
CLVS1	GCSAML	ENSP00000428402	ENSP00000446460	Clavesin-1; Required for normal morphology of late endosomes and/or lysosomes in neurons (By similarity). Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2)	Germinal center associated signaling and motility like	0.518
CLVS1	MTMR8	ENSP00000428402	ENSP00000363985	Clavesin-1; Required for normal morphology of late endosomes and/or lysosomes in neurons (By similarity). Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2)	Myotubularin-related protein 8; Phosphatase that acts on lipids with a phosphoinositol headgroup; Myotubularins	0.587
GCSAML	CCDC71L	ENSP00000446460	ENSP00000430897	Germinal center associated signaling and motility like	Coiled-coil domain-containing protein 71L; Coiled-coil domain containing 71 like	0.539
GCSAML	CLVS1	ENSP00000446460	ENSP00000428402	Germinal center associated signaling and motility like	Clavesin-1; Required for normal morphology of late endosomes and/or lysosomes in neurons (By similarity). Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2)	0.518
GCSAML	METTL20	ENSP00000446460	ENSP00000350353	Germinal center associated signaling and motility like	Electron transfer flavoprotein beta subunit lysine methyltransferase; Protein-lysine methyltransferase that selectively trimethylates the flavoprotein ETFB in mitochondria. Thereby, may negatively regulate the function of ETFB in electron transfer from Acyl-CoA dehydrogenases to the main respiratory chain	0.514
GCSAML	MTMR8	ENSP00000446460	ENSP00000363985	Germinal center associated signaling and motility like	Myotubularin-related protein 8; Phosphatase that acts on lipids with a phosphoinositol headgroup; Myotubularins	0.512

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